Prati
Kathleen B Yates
Kathleen B Yates
Broad Institute of MIT and Harvard
Potvrđena adresa e-pošte na broadinstitute.org
Naslov
Citirano
Citirano
Godina
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
BC Miller, DR Sen, R Al Abosy, K Bi, YV Virkud, MW LaFleur, KB Yates, ...
Nature immunology 20 (3), 326-336, 2019
13562019
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
RT Manguso, HW Pope, MD Zimmer, FD Brown, KB Yates, BC Miller, ...
Nature 547 (7664), 413-418, 2017
9782017
The epigenetic landscape of T cell exhaustion
DR Sen, J Kaminski, RA Barnitz, M Kurachi, U Gerdemann, KB Yates, ...
Science 354 (6316), 1165-1169, 2016
8262016
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
M Quigley, F Pereyra, B Nilsson, F Porichis, C Fonseca, Q Eichbaum, ...
Nature medicine 16 (10), 1147-1151, 2010
5852010
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
Cancer discovery 8 (2), 216-233, 2018
5802018
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
JJ Ishizuka, RT Manguso, CK Cheruiyot, K Bi, A Panda, A Iracheta-Vellve, ...
Nature 565 (7737), 43-48, 2019
4992019
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
PK Gupta, J Godec, D Wolski, E Adland, K Yates, KE Pauken, C Cosgrove, ...
PLoS pathogens 11 (10), e1005177, 2015
3822015
The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells
M Kurachi, RA Barnitz, N Yosef, PM Odorizzi, MA DiIorio, ME Lemieux, ...
Nature immunology 15 (4), 373-383, 2014
3432014
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity
GK Griffin, J Wu, A Iracheta-Vellve, JC Patti, J Hsu, T Davis, D Dele-Oni, ...
Nature 595 (7866), 309-314, 2021
2132021
PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity
MW LaFleur, TH Nguyen, MA Coxe, BC Miller, KB Yates, JE Gillis, ...
Nature immunology 20 (10), 1335-1347, 2019
1482019
Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans
KB Yates, P Tonnerre, GE Martin, U Gerdemann, R Al Abosy, ...
Nature immunology 22 (8), 1020-1029, 2021
1432021
A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system
MW LaFleur, TH Nguyen, MA Coxe, KB Yates, JD Trombley, SA Weiss, ...
Nature communications 10 (1), 1668, 2019
1002019
Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection
P Penaloza-MacMaster, DL Barber, EJ Wherry, NM Provine, JE Teigler, ...
Science 347 (6219), 278-282, 2015
832015
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation. Cancer Discov. 2018; 8: 216–233. doi: 10.1158/2159-8290
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
CD-17-0915.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
83
The PD-1 pathway regulates development and function of memory CD8+ T cells following respiratory viral infection
KE Pauken, J Godec, PM Odorizzi, KE Brown, KB Yates, SF Ngiow, ...
Cell reports 31 (13), 2020
802020
Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state
S Afik, KB Yates, K Bi, S Darko, J Godec, U Gerdemann, L Swadling, ...
Nucleic acids research 45 (16), e148-e148, 2017
792017
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
J Dubrot, PP Du, SK Lane-Reticker, EA Kessler, AJ Muscato, A Mehta, ...
Nature Immunology 23 (10), 1495-1506, 2022
692022
Maintenance of CD4 T cell fitness through regulation of Foxo1
RH Newton, S Shrestha, JM Sullivan, KB Yates, EB Compeer, ...
Nature immunology 19 (8), 838-848, 2018
672018
Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodeling
FD Brown, DR Sen, MW LaFleur, J Godec, V Lukacs-Kornek, ...
Nature immunology 20 (12), 1668-1680, 2019
602019
In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma
J Dubrot, SK Lane-Reticker, EA Kessler, A Ayer, G Mishra, CH Wolfe, ...
Immunity 54 (3), 571-585. e6, 2021
562021
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