Prati
Ahmet Acar
Naslov
Citirano
Citirano
Godina
Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
Y Kojima, A Acar, EN Eaton, KT Mellody, C Scheel, I Ben-Porath, ...
Proceedings of the National Academy of Sciences 107 (46), 20009-20014, 2010
7602010
Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity
BM Simões, CS O’Brien, R Eyre, A Silva, L Yu, A Sarmiento-Castro, ...
Cell reports 12 (12), 1968-1977, 2015
1672015
TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer
S Busch, A Acar, Y Magnusson, P Gregersson, L Rydén, G Landberg
Oncogene 34 (1), 27-38, 2013
982013
Dishevelled limits Notch signalling through inhibition of CSL
GM Collu, A Hidalgo-Sastre, A Acar, L Bayston, C Gildea, MK Leverentz, ...
Development 139 (23), 4405-4415, 2012
742012
A role for notch signalling in breast cancer and endocrine resistance
A Acar, BM Simões, RB Clarke, K Brennan
Stem cells international 2016, 2016
672016
Subclonal reconstruction of tumors by using machine learning and population genetics
G Caravagna, T Heide, MJ Williams, L Zapata, D Nichol, K Chkhaidze, ...
Nature Genetics 52 (9), 898-907, 2020
58*2020
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ...
Nature communications 11 (1), 1-14, 2020
54*2020
Evolutionary dynamics of residual disease in human glioblastoma
I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ...
Annals of Oncology 30 (3), 456-463, 2019
412019
The spatiotemporal evolution of lymph node spread in early breast cancer
P Barry, A Vatsiou, I Spiteri, D Nichol, GD Cresswell, A Acar, N Trahearn, ...
Clinical Cancer Research 24 (19), 4763-4770, 2018
292018
Experimental generation of carcinoma-associated fibroblasts (CAFs) from human mammary fibroblasts
UM Polanska, A Acar, A Orimo
JoVE (Journal of Visualized Experiments), e3201, 2011
222011
Inhibition of Wnt signalling by Notch via two distinct mechanisms
A Acar, A Hidalgo-Sastrem, MK Leverentz, CG Mills, W Simon, B Martin, ...
Scientific Reports, 9096, 2021
102021
Systems Biology and Experimental Model Systems of Cancer
GD Yalcin, N Danisik, RC Baygin, A Acar
Journal of Personalized Medicine 10 (4), 180, 2020
52020
Notch: evidence for combining therapies to treat breast cancer
MK Leverentz, A Acar, K Brennan
Breast Cancer Management 2 (6), 481-488, 2013
12013
Increased TRIM31 gene expression is positively correlated with SARS-CoV-2 associated genes TMPRSS2 and TMPRSS4 in gastrointestinal cancers
MA Temena, A Acar
Scientific reports 12 (1), 1-13, 2022
2022
Tumour evolvability metrics predict recurrence beyond 10 years in locally-advanced prostate cancer
J Fernandez-Mateos, G Cresswell, N Trahearn, K Webb, C Stuttle, ...
The Institute of Cancer Research, 2022
2022
Tumour evolvability metrics predict recurrence beyond 10 years in locally-advanced prostate cancer
A Sottoriva, J Fernandez-Mateos, G Cresswell, N Trahearn, K Webb, ...
2022
Developing quantitative experimental model systems to study drug resistance
A Acar
2021
DEVELOPING QUANTITATIVE EXPERIMENTAL MODEL SYSTEMS TO STUDY DRUG RESISTANCE
N Danisik, RC Baygin, MA Temena, A Acar
2021
Convolutional Neural Networks for Classification of Colorectal Cancer on Whole Slide Images
MA Temena, U Isildak, A Acar
2021
PO-498 Quantifying the dynamics of acquired treatment resistance and evolutionary herding for the prediction of collateral sensitivity in cancer model systems
A Acar, D Nichol, P Thavasu, I Sagastume, JF Mateos, M Stubbs, R Burke, ...
ESMO Open 3, A217, 2018
2018
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