Jonas Leichsenring
Jonas Leichsenring
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Implementing tumor mutational burden (TMB) analysis in routine diagnostics—a primer for molecular pathologists and clinicians
M Allgäuer, J Budczies, P Christopoulos, V Endris, A Lier, E Rempel, ...
Translational lung cancer research 7 (6), 703, 2018
Size matters: dissecting key parameters for panel‐based tumor mutational burden analysis
I Buchhalter, E Rempel, V Endris, M Allgäuer, O Neumann, AL Volckmar, ...
International journal of cancer 144 (4), 848-858, 2019
Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels
V Endris, I Buchhalter, M Allgäuer, E Rempel, A Lier, AL Volckmar, ...
International journal of cancer 144 (9), 2303-2312, 2019
Pan‐cancer analysis of copy number changes in programmed death‐ligand 1 (PD‐L1, CD274)–associations with gene expression, mutational load, and survival
J Budczies, M Bockmayr, C Denkert, F Klauschen, S Gröschel, ...
Genes, Chromosomes and Cancer 55 (8), 626-639, 2016
Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: analysis of the first 3,000 Heidelberg cases
AL Volckmar, J Leichsenring, M Kirchner, P Christopoulos, O Neumann, ...
International Journal of Cancer 145 (3), 649-661, 2019
Variant classification in precision oncology
J Leichsenring, P Horak, S Kreutzfeldt, C Heining, P Christopoulos, ...
International journal of cancer 145 (11), 2996-3010, 2019
Targeted therapy in advanced melanoma with rare BRAF mutations
C Menzer, AM Menzies, MS Carlino, I Reijers, EJ Groen, T Eigentler, ...
Journal of Clinical Oncology 37 (33), 3142, 2019
Spatial and temporal heterogeneity of panel-based tumor mutational burden in pulmonary adenocarcinoma: separating biology from technical artifacts
D Kazdal, V Endris, M Allgäuer, M Kriegsmann, J Leichsenring, ...
Journal of Thoracic Oncology 14 (11), 1935-1947, 2019
Patients resistant against PSMA-targeting α-radiation therapy often harbor mutations in DNA damage-repair–associated genes
C Kratochwil, FL Giesel, CP Heussel, D Kazdal, V Endris, C Nientiedt, ...
Journal of Nuclear Medicine 61 (5), 683-688, 2020
Testing NTRK testing: Wet‐lab and in silico comparison of RNA‐based targeted sequencing assays
N Pfarr, M Kirchner, U Lehmann, J Leichsenring, S Merkelbach‐Bruse, ...
Genes, Chromosomes and Cancer 59 (3), 178-188, 2020
Taxon‐and vector‐specific variation in species richness and abundance during the transport stage of biological invasions
E Briski, SA Bailey, O Casas-Monroy, C DiBacco, I Kaczmarska, ...
Limnology and Oceanography 58 (4), 1361-1372, 2013
The BRCA2 mutation status shapes the immune phenotype of prostate cancer
M Jenzer, P Keß, C Nientiedt, V Endris, M Kippenberger, J Leichsenring, ...
Cancer Immunology, Immunotherapy 68, 1621-1633, 2019
RNA-based detection of gene fusions in formalin-fixed and paraffin-embedded solid cancer samples
M Kirchner, O Neumann, AL Volckmar, F Stögbauer, M Allgäuer, D Kazdal, ...
Cancers 11 (9), 1309, 2019
Detection of TP53 Mutations in Tissue or Liquid Rebiopsies at Progression Identifies ALK+ Lung Cancer Patients with Poor Survival
P Christopoulos, S Dietz, M Kirchner, AL Volckmar, V Endris, O Neumann, ...
Cancers 11 (1), 124, 2019
The value of prostate-specific antigen density for prostate imaging-reporting and data system 3 lesions on multiparametric magnetic resonance imaging: A strategy to avoid …
M Görtz, JP Radtke, G Hatiboglu, V Schütz, G Tosev, M Güttlein, ...
European urology focus 7 (2), 325-331, 2021
Targeted molecular profiling reveals genetic heterogeneity of poromas and porocarcinomas
M Bosic, M Kirchner, D Brasanac, J Leichsenring, A Lier, AL Volckmar, ...
Pathology 50 (3), 327-332, 2018
Targeted next‐generation sequencing enables reliable detection of HER2 (ERBB2) status in breast cancer and provides ancillary information of clinical relevance
N Pfarr, R Penzel, V Endris, C Lier, C Flechtenmacher, AL Volckmar, ...
Genes, Chromosomes and Cancer 56 (4), 255-265, 2017
Combined immunohistochemistry after mass spectrometry imaging for superior spatial information
K Kriegsmann, R Longuespée, M Hundemer, C Zgorzelski, R Casadonte, ...
PROTEOMICS–Clinical Applications 13 (1), 1800035, 2019
Tubular, lactating, and ductal adenomas are devoid of MED12 Exon2 mutations, and ductal adenomas show recurrent mutations in GNAS and the PI3K–AKT pathway
AL Volckmar, J Leichsenring, C Flechtenmacher, N Pfarr, U Siebolts, ...
Genes, Chromosomes and Cancer 56 (1), 11-17, 2017
Comparative genetic profiling aids diagnosis and clinical decision making in challenging cases of CUP syndrome
T Bochtler, V Endris, J Leichsenring, A Reiling, O Neumann, AL Volckmar, ...
International journal of cancer 145 (11), 2963-2973, 2019
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