Prati
Emily P. Balskus
Emily P. Balskus
Professor of Chemistry and Chemical Biology
Potvrđena adresa e-pošte na chemistry.harvard.edu - Početna stranica
Naslov
Citirano
Citirano
Godina
Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
8392015
Chemical transformation of xenobiotics by the human gut microbiota
N Koppel, V Maini Rekdal, EP Balskus
Science 356 (6344), eaag2770, 2017
8152017
Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme
S Craciun, EP Balskus
Proceedings of the National Academy of Sciences 109 (52), 21307-21312, 2012
6762012
Predicting and manipulating cardiac drug inactivation by the human gut bacterium Eggerthella lenta
HJ Haiser, DB Gootenberg, K Chatman, G Sirasani, EP Balskus, ...
Science 341 (6143), 295-298, 2013
6722013
Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism
V Maini Rekdal, EN Bess, JE Bisanz, PJ Turnbaugh, EP Balskus
Science 364 (6445), eaau6323, 2019
5512019
The human gut bacterial genotoxin colibactin alkylates DNA
MR Wilson, Y Jiang, PW Villalta, A Stornetta, PD Boudreau, A Carrá, ...
Science 363 (6428), eaar7785, 2019
4312019
The genetic and molecular basis for sunscreen biosynthesis in cyanobacteria
EP Balskus, CT Walsh
Science 329 (5999), 1653-1656, 2010
3942010
Trimethylamine N-oxide binds and activates PERK to promote metabolic dysfunction
S Chen, A Henderson, MC Petriello, KA Romano, M Gearing, J Miao, ...
Cell metabolism 30 (6), 1141-1151. e5, 2019
2542019
A prodrug resistance mechanism is involved in colibactin biosynthesis and cytotoxicity
CA Brotherton, EP Balskus
Journal of the American Chemical Society 135 (9), 3359-3362, 2013
1802013
Cholesterol metabolism by uncultured human gut bacteria influences host cholesterol level
DJ Kenny, DR Plichta, D Shungin, N Koppel, AB Hall, B Fu, RS Vasan, ...
Cell host & microbe 28 (2), 245-257. e6, 2020
1762020
Mechanistic insight into digoxin inactivation by Eggerthella lenta augments our understanding of its pharmacokinetics
HJ Haiser, KL Seim, EP Balskus, PJ Turnbaugh
Gut microbes 5 (2), 233-238, 2014
1752014
Characterization and detection of a widely distributed gene cluster that predicts anaerobic choline utilization by human gut bacteria
A Martínez-del Campo, S Bodea, HA Hamer, JA Marks, HJ Haiser, ...
MBio 6 (2), 10.1128/mbio. 00042-15, 2015
1692015
α, β-Unsaturated β-Silyl Imide Substrates for Catalytic, Enantioselective Conjugate Additions: A Total Synthesis of (+)-Lactacystin and the Discovery of a New Proteasome Inhibitor
EP Balskus, EN Jacobsen
Journal of the American Chemical Society 128 (21), 6810-6812, 2006
1652006
Metabolic, epigenetic, and transgenerational effects of gut bacterial choline consumption
KA Romano, A Martinez-del Campo, K Kasahara, CL Chittim, EI Vivas, ...
Cell host & microbe 22 (3), 279-290. e7, 2017
1602017
Investigating the initial steps in the biosynthesis of cyanobacterial sunscreen scytonemin
EP Balskus, CT Walsh
Journal of the American Chemical Society 130 (46), 15260-15261, 2008
1592008
A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans-4-hydroxy-l-proline
BJ Levin, YY Huang, SC Peck, Y Wei, A Martinez-Del Campo, JA Marks, ...
Science 355 (6325), eaai8386, 2017
1482017
Heteroatom–heteroatom bond formation in natural product biosynthesis
AJ Waldman, TL Ng, P Wang, EP Balskus
Chemical Reviews 117 (8), 5784-5863, 2017
1452017
Exploring and understanding the biochemical diversity of the human microbiota
N Koppel, EP Balskus
Cell chemical biology 23 (1), 18-30, 2016
1362016
Spin-transition behaviour in chains of Fe II bridged by 4-substituted 1, 2, 4-triazoles carrying alkyl tails
O Roubeau, JMA Gomez, E Balskus, JJA Kolnaar, JG Haasnoot, ...
New Journal of Chemistry 25 (1), 144-150, 2001
1362001
Characterization of choline trimethylamine-lyase expands the chemistry of glycyl radical enzymes
S Craciun, JA Marks, EP Balskus
ACS chemical biology 9 (7), 1408-1413, 2014
1342014
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