| Reactive astrocyte nomenclature, definitions, and future directions C Escartin, E Galea, A Lakatos, JP O’Callaghan, GC Petzold, ... Nature neuroscience 24 (3), 312-325, 2021 | 1857 | 2021 |
| CRISPR/Cas9 mediated disruption of the Swedish APP allele as a therapeutic approach for early-onset Alzheimer’s disease B György, C Lööv, MP Zaborowski, S Takeda, BP Kleinstiver, C Commins, ... Molecular therapy Nucleic acids 11, 429-440, 2018 | 188 | 2018 |
| Cerebrospinal fluid amyloid-β 42/40 ratio in clinical setting of memory centers: a multicentric study J Dumurgier, S Schraen, A Gabelle, O Vercruysse, S Bombois, ... Alzheimer's research & therapy 7, 1-9, 2015 | 163 | 2015 |
| Immunotherapy with aducanumab restores calcium homeostasis in Tg2576 mice KV Kastanenka, T Bussiere, N Shakerdge, F Qian, PH Weinreb, K Rhodes, ... Journal of neuroscience 36 (50), 12549-12558, 2016 | 118 | 2016 |
| Optogenetic restoration of disrupted slow oscillations halts amyloid deposition and restores calcium homeostasis in an animal model of Alzheimer’s disease KV Kastanenka, SS Hou, N Shakerdge, R Logan, D Feng, S Wegmann, ... PloS one 12 (1), e0170275, 2017 | 105 | 2017 |
| Slow wave sleep is a promising intervention target for Alzheimer’s disease YF Lee, D Gerashchenko, I Timofeev, BJ Bacskai, KV Kastanenka Frontiers in neuroscience 14, 705, 2020 | 100 | 2020 |
| A roadmap to integrate astrocytes into Systems Neuroscience KV Kastanenka, R Moreno‐Bote, M De Pittà, G Perea, A Eraso‐Pichot, ... Glia 68 (1), 5-26, 2020 | 82 | 2020 |
| In vivo activation of channelrhodopsin-2 reveals that normal patterns of spontaneous activity are required for motoneuron guidance and maintenance of guidance molecules KV Kastanenka, LT Landmesser Journal of Neuroscience 30 (31), 10575-10585, 2010 | 59 | 2010 |
| Building transformers from neurons and astrocytes L Kozachkov, KV Kastanenka, D Krotov Proceedings of the National Academy of Sciences 120 (34), e2219150120, 2023 | 55 | 2023 |
| Frequency-dependent modes of synaptic vesicle endocytosis and exocytosis at adult mouse neuromuscular junctions Y Maeno-Hikichi, L Polo-Parada, KV Kastanenka, LT Landmesser Journal of Neuroscience 31 (3), 1093-1105, 2011 | 51 | 2011 |
| Frequency-dependent exacerbation of Alzheimer’s disease neuropathophysiology KV Kastanenka, M Calvo-Rodriguez, SS Hou, H Zhou, S Takeda, ... Scientific reports 9 (1), 8964, 2019 | 49 | 2019 |
| Pathogenic PS1 phosphorylation at Ser367 M Maesako, J Horlacher, KM Zoltowska, KV Kastanenka, E Kara, ... elife 6, e19720, 2017 | 31 | 2017 |
| Reduced excitatory neuron activity and interneuron-type-specific deficits in a mouse model of Alzheimer’s disease M Algamal, AN Russ, MR Miller, SS Hou, M Maci, LP Munting, Q Zhao, ... Communications biology 5 (1), 1323, 2022 | 24 | 2022 |
| An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging X Wang, KV Kastanenka, M Arbel-Ornath, C Commins, A Kuzuya, ... Scientific Reports 8 (1), 4634, 2018 | 23 | 2018 |
| Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer’s disease model Q Zhao, M Maci, MR Miller, H Zhou, F Zhang, M Algamal, YF Lee, SS Hou, ... Molecular Neurodegeneration 18 (1), 93, 2023 | 20 | 2023 |
| Optogenetic-mediated increases in in vivo spontaneous activity disrupt pool-specific but not dorsal-ventral motoneuron pathfinding KV Kastanenka, LT Landmesser Proceedings of the National Academy of Sciences 110 (43), 17528-17533, 2013 | 18 | 2013 |
| Novel botanical drug DA-9803 prevents deficits in Alzheimer’s mouse models GJ Pagnier, KV Kastanenka, M Sohn, S Choi, S Choi, HY Soh, BJ Bacskai Alzheimer's research & therapy 10, 1-13, 2018 | 16 | 2018 |
| Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer’s disease pathology YF Lee, AN Russ, Q Zhao, SJ Perle, M Maci, MR Miller, SS Hou, ... Scientific reports 13 (1), 13075, 2023 | 13 | 2023 |
| Optical probes for in vivo brain imaging KV Kastanenka, M Arbel-Ornath, E Hudry, E Galea, H Xie, BJ Bacskai Optical probes in biology, 355-376, 2015 | 7 | 2015 |
| Novel botanical therapeutic NB-02 effectively treats Alzheimer’s neuropathophysiology in an APP/PS1 mouse model YF Lee, L Lariviere, AN Russ, SZ Choi, BJ Bacskai, KV Kastanenka Eneuro 8 (3), 2021 | 6 | 2021 |
Brian BacskaiMassachusetts general hospitalVerified email at partners.org
