Prati
Rajni M. Bhardwaj
Rajni M. Bhardwaj
Potvrđena adresa e-pošte na abbvie.com
Naslov
Citirano
Citirano
Godina
Exploring the Experimental and Computed Crystal Energy Landscape of Olanzapine
RM Bhardwaj, LS Price, SL Price, SM Reutzel-Edens, GJ Miller, ...
Crystal Growth & Design 13 (4), 1602-1617, 2013
1312013
A prolific solvate former, galunisertib, under the pressure of crystal structure prediction, produces ten diverse polymorphs
RM Bhardwaj, JA McMahon, J Nyman, LS Price, S Konar, IDH Oswald, ...
Journal of the American Chemical Society 141 (35), 13887-13897, 2019
1282019
The complex polymorphic system of gallic acid-five monohydrates, three anhydrates and over 20 solvates
DE Braun, RM Bhardwaj, AJ Florence, DA Tocher, SL Price
Crystal Growth & Design 13 (1), 19-23, 2013
1092013
From discovery to scale-up: α-lipoic acid: nicotinamide co-crystals in a continuous oscillatory baffled crystalliser
L Zhao, V Raval, NEB Briggs, RM Bhardwaj, T McGlone, IDH Oswald, ...
CrystEngComm 16 (26), 5769-5780, 2014
972014
Protein kinase inhibitors: structural insights into selectivity
R Thaimattam, R Banerjee, R Miglani, J Iqbal
Current pharmaceutical design 13 (27), 2751-2765, 2007
772007
Mode of action of ranbezolid against staphylococci and structural modeling studies of its interaction with ribosomes
V Kalia, R Miglani, KP Purnapatre, T Mathur, S Singhal, S Khan, SR Voleti, ...
Antimicrobial agents and chemotherapy 53 (4), 1427-1433, 2009
512009
Direct observation of templated two-step nucleation mechanism during olanzapine hydrate formation
M Warzecha, R Guo, R M. Bhardwaj, SM Reutzel-Edens, SL Price, ...
Crystal Growth & Design 17 (12), 6382-6393, 2017
502017
Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1 …
J Hao, JP Beck, JM Schaus, JH Krushinski, Q Chen, CD Beadle, P Vidal, ...
Journal of medicinal chemistry 62 (19), 8711-8732, 2019
492019
Absorbing a little water: the structural, thermodynamic, and kinetic relationship between pyrogallol and its tetarto-hydrate
DE Braun, RM Bhardwaj, JB Arlin, AJ Florence, V Kahlenberg, ...
Crystal growth & design 13 (9), 4071-4083, 2013
392013
Inconvenient Truths about Solid Form Landscapes Revealed in the Polymorphs and Hydrates of Gandotinib
DE Braun, JA McMahon, RM Bhardwaj, J Nyman, MA Neumann, ...
Crystal Growth & Design 19 (5), 2947-2962, 2019
362019
Modeling olanzapine solution growth morphologies
Y Sun, CJ Tilbury, SM Reutzel-Edens, RM Bhardwaj, J Li, MF Doherty
Crystal Growth & Design 18 (2), 905-911, 2018
362018
Drug solid solutions–a method for tuning phase transformations
A Delori, P Maclure, RM Bhardwaj, A Johnston, AJ Florence, OB Sutcliffe, ...
CrystEngComm 16 (26), 5827-5831, 2014
342014
A random forest model for predicting the crystallisability of organic molecules
RM Bhardwaj, A Johnston, BF Johnston, AJ Florence
CrystEngComm 17 (23), 4272-4275, 2015
312015
Spray drying as a reliable route to produce metastable carbamazepine form IV
RA Halliwell, RM Bhardwaj, CJ Brown, NEB Briggs, J Dunn, J Robertson, ...
Journal of pharmaceutical sciences 106 (7), 1874-1880, 2017
282017
Implications of the Conformationally Flexible, Macrocyclic Structure of the First-Generation, Direct-Acting Anti-Viral Paritaprevir on Its Solid Form Complexity and Chameleonic …
AY Sheikh, A Mattei, R Miglani Bhardwaj, RS Hong, NS Abraham, ...
Journal of the American Chemical Society 143 (42), 17479-17491, 2021
272021
Synthesis and Pharmacological Characterization of C4β-Amide-Substituted 2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1S,2S,4S,5R,6S)-2-Amino-4 …
JA Monn, SS Henry, SM Massey, DK Clawson, Q Chen, BA Diseroad, ...
Journal of medicinal chemistry 61 (6), 2303-2328, 2018
252018
Structure and stability of two polymorphs of creatine and its monohydrate
JB Arlin, RM Bhardwaj, A Johnston, GJ Miller, J Bardin, F MacDougall, ...
CrystEngComm 16 (35), 8197-8204, 2014
212014
Novel Physics-Based Ensemble Modeling Approach That Utilizes 3D Molecular Conformation and Packing to Access Aqueous Thermodynamic Solubility: A Case Study of Orally Available …
RS Hong, A Mattei, AY Sheikh, RM Bhardwaj, MA Bellucci, KF McDaniel, ...
Journal of Chemical Information and Modeling 61 (3), 1412-1426, 2021
152021
A random forest model for predicting crystal packing of olanzapine solvates
RM Bhardwaj, SM Reutzel-Edens, BF Johnston, AJ Florence
CrystEngComm 20 (28), 3947-3950, 2018
142018
Crystal forms in pharmaceutical applications: olanzapine, a gift to crystal chemistry that keeps on giving
SM Reutzel-Edens, RM Bhardwaj
IUCrJ 7 (6), 955-964, 2020
132020
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