Prati
Fabrice Le Boeuf
Fabrice Le Boeuf
Ottawa Hospital Research Institute
Potvrđena adresa e-pošte na ohri.ca
Naslov
Citirano
Citirano
Godina
Endothelial cell migration during angiogenesis
L Lamalice, F Le Boeuf, J Huot
Circulation research 100 (6), 782-794, 2007
18022007
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
CJ Breitbach, J Burke, D Jonker, J Stephenson, AR Haas, LQM Chow, ...
Nature 477 (7362), 99-102, 2011
6432011
The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers
KA Parato, CJ Breitbach, F Le Boeuf, J Wang, C Storbeck, C Ilkow, ...
Molecular Therapy 20 (4), 749-758, 2012
3282012
Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus
DH Kirn, Y Wang, F Le Boeuf, J Bell, SH Thorne
PLoS medicine 4 (12), e353, 2007
2542007
Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities
F Le Boeuf, F Houle, J Huot
Journal of Biological Chemistry 279 (37), 39175-39185, 2004
1822004
Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase
M Duval, F Le Bœuf, J Huot, JP Gratton
Molecular biology of the cell 18 (11), 4659-4668, 2007
1752007
Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity
CS Ilkow, M Marguerie, C Batenchuk, J Mayer, D Ben Neriah, ...
Nature medicine 21 (5), 530-536, 2015
1612015
Synergistic interaction between oncolytic viruses augments tumor killing
F Le Boeuf, JS Diallo, JA McCart, S Thorne, T Falls, M Stanford, F Kanji, ...
Molecular Therapy 18 (5), 888-895, 2010
1592010
Smac mimetics and innate immune stimuli synergize to promote tumor death
ST Beug, VA Tang, EC LaCasse, HH Cheung, CE Beauregard, J Brun, ...
Nature biotechnology 32 (2), 182-190, 2014
1462014
Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine
CG Lemay, JL Rintoul, A Kus, JM Paterson, V Garcia, TJ Falls, L Ferreira, ...
Molecular Therapy 20 (9), 1791-1799, 2012
1252012
VEGF-mediated induction of PRD1-BF1/Blimp1 expression sensitizes tumor vasculature to oncolytic virus infection
R Arulanandam, C Batenchuk, FA Angarita, K Ottolino-Perry, ...
Cancer Cell 28 (2), 210-224, 2015
1182015
A high-throughput pharmacoviral approach identifies novel oncolytic virus sensitizers
JS Diallo, F Le Boeuf, F Lai, J Cox, M Vaha-Koskela, H Abdelbary, ...
Molecular Therapy 18 (6), 1123-1129, 2010
1172010
Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2–mediated phosphorylation of FAK …
F Le Boeuf, F Houle, M Sussman, J Huot
Molecular biology of the cell 17 (8), 3508-3520, 2006
932006
Multi-modal potentiation of oncolytic virotherapy by vanadium compounds
M Selman, C Rousso, A Bergeron, HH Son, R Krishnan, NA El-Sayes, ...
Molecular Therapy 26 (1), 56-69, 2018
862018
Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors
H MacTavish, JS Diallo, B Huang, M Stanford, F Le Boeuf, N De Silva, ...
PLoS One 5 (12), e14462, 2010
842010
Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors
JG Pol, S Levesque, ST Workenhe, S Gujar, F Le Boeuf, DR Clements, ...
Oncoimmunology 7 (12), e1503032, 2018
762018
RhoA activation mediates phosphatidylinositol 3-kinase–dependent proliferation of human vascular endothelial cells: an alloimmune mechanism of chronic allograft nephropathy
F Leboeuf, JP Soulillou
Journal of the American Society of Nephrology 15 (9), 2429-2439, 2004
752004
Antiangiogenic arming of an oncolytic vaccinia virus enhances antitumor efficacy in renal cell cancer models
K Guse, M Sloniecka, I Diaconu, K Ottolino-Perry, N Tang, C Ng, ...
Journal of virology 84 (2), 856-866, 2010
742010
Propagation, purification, and in vivo testing of oncolytic vesicular stomatitis virus strains
JS Diallo, M Vähä-Koskela, F Le Boeuf, J Bell
Oncolytic Viruses: Methods and Protocols, 127-140, 2012
702012
Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing
R Arulanandam, C Batenchuk, O Varette, C Zakaria, V Garcia, NE Forbes, ...
Nature communications 6 (1), 6410, 2015
652015
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