Shengyun Fang
Shengyun Fang
Associate Professor, University of Maryland School of Medicine, Center for Biomedical Engineering
Verified email at
Cited by
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
KL Lorick, JP Jensen, S Fang, AM Ong, S Hatakeyama, AM Weissman
Proceedings of the National Academy of Sciences 96 (20), 11364-11369, 1999
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
S Fang, JP Jensen, RL Ludwig, KH Vousden, AM Weissman
Journal of Biological Chemistry 275 (12), 8945-8951, 2000
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
Y Yang, S Fang, JP Jensen, AM Weissman, JD Ashwell
Science 288 (5467), 874-877, 2000
SINAT5 promotes ubiquitin-related degradation of NAC1 to attenuate auxin signals
Q Xie, HS Guo, G Dallman, S Fang, AM Weissman, NH Chua
Nature 419 (6903), 167-170, 2002
The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum
S Fang, M Ferrone, C Yang, JP Jensen, S Tiwari, AM Weissman
Proceedings of the National Academy of Sciences 98 (25), 14422-14427, 2001
A field guide to ubiquitylation.
S Fang, AM Weissman
Cellular and molecular life sciences: CMLS 61 (13), 1546, 2004
Glycogen synthase kinase 3β (GSK3β) mediates 6‐hydroxydopamine‐induced neuronal death
G Chen, KA Bower, C Ma, S Fang, CJ Thiele, JIA Luo
The FASEB journal 18 (10), 1162-1164, 2004
Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death
A Apostolou, Y Shen, Y Liang, J Luo, S Fang
Experimental cell research 314 (13), 2454-2467, 2008
AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation
X Zhong, Y Shen, P Ballar, A Apostolou, R Agami, S Fang
Journal of Biological Chemistry 279 (44), 45676-45684, 2004
WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation
A Magnifico, S Ettenberg, C Yang, J Mariano, S Tiwari, S Fang, ...
Journal of Biological Chemistry 278 (44), 43169-43177, 2003
The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover
S Xu, G Peng, Y Wang, S Fang, M Karbowski
Molecular biology of the cell 22 (3), 291-300, 2011
Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination
K Xu, H Shimelis, DE Linn, R Jiang, X Yang, F Sun, Z Guo, H Chen, W Li, ...
Cancer cell 15 (4), 270-282, 2009
Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer
J Zhang, Y Jiang, Z Jia, Q Li, W Gong, L Wang, D Wei, J Yao, S Fang, ...
Clinical & experimental metastasis 23 (7-8), 401-410, 2006
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
C Rothenberg, D Srinivasan, L Mah, S Kaushik, CM Peterhoff, J Ugolino, ...
Human molecular genetics 19 (16), 3219-3232, 2010
Selective Inhibition of Endoplasmic Reticulum-associated Degradation Rescues ΔF508-Cystic Fibrosis Transmembrane Regulator and Suppresses Interleukin-8 Levels THERAPEUTIC …
N Vij, S Fang, PL Zeitlin
Journal of Biological Chemistry 281 (25), 17369-17378, 2006
RING finger ubiquitin protein ligases: implications for tumorigenesis, metastasis and for molecular targets in cancer
S Fang, KL Lorick, JP Jensen, AM Weissman
Seminars in cancer biology 13 (1), 5-14, 2003
CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation accumulation of poly-ubiquitinated hsp90 client proteins
H Doong, K Rizzo, S Fang, V Kulpa, AM Weissman, EC Kohn
Journal of Biological Chemistry 278 (31), 28490-28500, 2003
The role of a novel p97/valosin-containing protein-interacting motif of gp78 in endoplasmic reticulum-associated degradation
P Ballar, Y Shen, H Yang, S Fang
Journal of Biological Chemistry 281 (46), 35359-35368, 2006
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD
PJ Lim, R Danner, J Liang, H Doong, C Harman, D Srinivasan, ...
Journal of Cell Biology 187 (2), 201-217, 2009
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