Aleksandr B. Sahakyan
Aleksandr B. Sahakyan
Group Leader and PI, Integrative Comp. Biology and Machine Learning, WIMM, RDM, University of Oxford
Potvrđena adresa e-pošte na - Početna stranica
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome
CK Kwok, G Marsico, AB Sahakyan, VS Chambers, S Balasubramanian
Nature methods 13 (10), 841-844, 2016
Whole genome experimental maps of DNA G-quadruplexes in multiple species
G Marsico, VS Chambers, AB Sahakyan, P McCauley, JM Boutell, ...
Nucleic acids research 47 (8), 3862-3874, 2019
Machine learning model for sequence-driven DNA G-quadruplex formation
AB Sahakyan, VS Chambers, G Marsico, T Santner, M Di Antonio, ...
Scientific reports 7 (1), 14535, 2017
Structural analysis using SHALiPE to reveal RNA G‐quadruplex formation in human precursor microRNA
CK Kwok, AB Sahakyan, S Balasubramanian
Angewandte Chemie 128 (31), 9104-9107, 2016
Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism
C Camilloni, AB Sahakyan, MJ Holliday, NG Isern, F Zhang, ...
Proceedings of the National Academy of Sciences 111 (28), 10203-10208, 2014
G-quadruplex structures within the 3′ UTR of LINE-1 elements stimulate retrotransposition
AB Sahakyan, P Murat, C Mayer, S Balasubramanian
Nature Structural and Molecular Biology 24, 2017
Structure-based prediction of methyl chemical shifts in proteins
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Journal of biomolecular NMR 50, 331-346, 2011
Selective chemical labeling of natural T modifications in DNA
RE Hardisty, F Kawasaki, AB Sahakyan, S Balasubramanian
Journal of The American Chemical Society 137 (29), 9270-9272, 2015
Thermal and pH stabilities of i‐DNA: confronting in vitro experiments with models and in‐cell NMR data
M Cheng, D Qiu, L Tamon, E Ištvánková, P Víšková, S Amrane, A Guédin, ...
Angewandte Chemie International Edition 60 (18), 10286-10294, 2021
Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs
KL Chan, B Peng, MI Umar, CY Chan, AB Sahakyan, MTN Le, CK Kwok
Chemical communications 54 (77), 10878-10881, 2018
ALMOST: an all atom molecular simulation toolkit for protein structure determination
B Fu, AB Sahakyan, C Camilloni, GG Tartaglia, E Paci, A Caflisch, ...
Journal of Computational Chemistry 35 (14), 1101-1105, 2014
Analysis of the contributions of ring current and electric field effects to the chemical shifts of RNA bases
AB Sahakyan, M Vendruscolo
The Journal of Physical Chemistry B 117 (7), 1989-1998, 2013
Long genes and genes with multiple splice variants are enriched in pathways linked to cancer and other multigenic diseases
AB Sahakyan, S Balasubramanian
BMC Genomics 17 (1), 225, 2016
Using Side‐Chain Aromatic Proton Chemical Shifts for a Quantitative Analysis of Protein Structures
AB Sahakyan, WF Vranken, A Cavalli, M Vendruscolo
Angewandte Chemie International Edition 50 (41), 9620-9623, 2011
A conformational ensemble derived using NMR methyl chemical shifts reveals a mechanical clamping transition that gates the binding of the HU protein to DNA
A Kannan, C Camilloni, AB Sahakyan, A Cavalli, M Vendruscolo
Journal of the American Chemical Society 136 (6), 2204-2207, 2014
Electric Field Effects on One-Bond Indirect Spin− Spin Coupling Constants and Possible Biomolecular Perspectives
AB Sahakyan, AG Shahkhatuni, AA Shahkhatuni, HA Panosyan
The Journal of Physical Chemistry A 112 (16), 3576-3586, 2008
Dielectric permittivity and temperature effects on spin–spin couplings studied on acetonitrile
AB Sahakyan, AA Shahkhatuni, AG Shahkhatuni, HA Panosyan
Magnetic Resonance in Chemistry 46 (1), 63-68, 2008
A geometrical parametrization of C1′-C5′ RNA ribose chemical shifts calculated by density functional theory
R Suardíaz, AB Sahakyan, M Vendruscolo
The Journal of Chemical Physics 139 (3), 034101, 2013
Correlation of 1JCH spin–spin coupling constants and their solvent sensitivities
AA Shahkhatuni, AB Sahakyan, AG Shahkhatuni, SS Mamyan, ...
Chemical Physics Letters 542, 56-61, 2012
Assessment of solvent effects: do weak alignment media affect the structure of the solute?
AA Shahkhatuni, AG Shahkhatuni, HA Panosyan, AB Sahakyan, ...
Magnetic Resonance in Chemistry 45 (7), 557-563, 2007
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