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Elda Grabocka
Elda Grabocka
Assistant Professor, Thomas Jefferson University
Potvrđena adresa e-pošte na jefferson.edu - Početna stranica
Naslov
Citirano
Citirano
Godina
RAS oncogenes: weaving a tumorigenic web
Y Pylayeva-Gupta, E Grabocka, D Bar-Sagi
Nature Reviews Cancer 11 (11), 761-774, 2011
17642011
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
C Commisso, SM Davidson, RG Soydaner-Azeloglu, SJ Parker, ...
Nature 497 (7451), 633-637, 2013
13032013
Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein
JJ Kamphorst, M Nofal, C Commisso, SR Hackett, W Lu, E Grabocka, ...
Cancer research 75 (3), 544-553, 2015
6042015
Wild-type H-and N-Ras promote mutant K-Ras-driven tumorigenesis by modulating the DNA damage response
E Grabocka, Y Pylayeva-Gupta, MJK Jones, V Lubkov, E Yemanaberhan, ...
Cancer cell 25 (2), 243-256, 2014
1392014
Mutant KRAS enhances tumor cell fitness by upregulating stress granules
E Grabocka, D Bar-Sagi
Cell 167 (7), 1803-1813. e12, 2016
1072016
Molecular Pathways: Targeting the Dependence of Mutant RAS Cancers on the DNA Damage ResponseRAS and DNA Damage
E Grabocka, C Commisso, D Bar-Sagi
Clinical cancer research 21 (6), 1243-1247, 2015
452015
Disruption of oligomerization induces nucleocytoplasmic shuttling of leukemia-associated rho Guanine-nucleotide exchange factor
E Grabocka, PB Wedegaertner
Molecular pharmacology 72 (4), 993-1002, 2007
332007
Functional consequences of Gα13 mutations that disrupt interaction with p115RhoGEF
E Grabocka, PB Wedegaertner
Oncogene 24 (13), 2155-2165, 2005
302005
Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission
MK Martz, E Grabocka, N Beeharry, TJ Yen, PB Wedegaertner
Molecular biology of the cell 24 (18), 2785-2794, 2013
292013
Stress granules in cancer
MS Song, E Grabocka
Springer, Berlin, Heidelberg, 2020
132020
Histological image processing features induce a quantitative characterization of chronic tumor hypoxia
A Sundstrom, E Grabocka, D Bar-Sagi, B Mishra
PloS one 11 (4), e0153623, 2016
102016
Evaluating stress granules in pancreatic cancer in vitro and in vivo
E Sim, E Irollo, E Grabocka
Pancreatic Cancer, 183-195, 2019
52019
Mitotic-dependent phosphorylation of leukemia-associated RhoGEF (LARG) by Cdk1
MC Helms, E Grabocka, MK Martz, CC Fischer, N Suzuki, ...
Cellular signalling 28 (1), 43-52, 2016
52016
RAS-mediated tumor stress adaptation and the targeting opportunities it presents
A Redding, AE Aplin, E Grabocka
Disease Models & Mechanisms 15 (2), dmm049280, 2022
32022
A phase Ib study combining irinotecan with AZD1775, a selective WEE 1 kinase inhibitor, in RAS/RAF mutated metastatic colorectal cancer patients who progressed on first line …
DJ Cohen, E Grabocka, D Bar-Sagi, R Godin, LP Leichman
Journal of Clinical Oncology 35 (15_suppl), TPS3627-TPS3627, 2017
32017
Raf-1 and squamous cell carcinoma: Rok-ing the boat
E Grabocka, D Bar-Sagi
Cancer Cell 16 (2), 85-86, 2009
32009
Stress Granules determine the Development of Obesity-associated Pancreatic Cancer
G Fonteneau, A Redding, H Hoag-Lee, ES Sim, S Heinrich, MM Gaida, ...
Cancer Discovery, 2022
2022
Stress Granules in Pancreatic Cancer: Drug Resistance & Treatment
E Grabocka, D Bar-Sagi
Oncology Times 39 (4), 30-34, 2017
2017
Selective sensitization of Ras-mutant (Ras-m) cancer cells to DNA-damaging chemotherapy by Wee1 inhibition with AZD1775.
E Grabocka, M Choi, DJ Cohen, R Godin, LP Leichman, D Bar-Sagi
Journal of Clinical Oncology 33 (15_suppl), e13517-e13517, 2015
2015
Mitotic-Dependent Phosphorylation of LARG by Cdk1
MC Helms, E Grabocka, MK Martz, N Suzuki, PB Wedegaertner
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY 103 (5), 409-409, 2015
2015
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