In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target RT Manguso, HW Pope, MD Zimmer, FD Brown, KB Yates, BC Miller, ... Nature 547 (7664), 413-418, 2017 | 982 | 2017 |
PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity VR Juneja, KA McGuire, RT Manguso, MW LaFleur, N Collins, ... Journal of Experimental Medicine 214 (4), 895-904, 2017 | 794 | 2017 |
Melanoma cell-intrinsic PD-1 receptor functions promote tumor growth S Kleffel, C Posch, SR Barthel, H Mueller, C Schlapbach, E Guenova, ... Cell 162 (6), 1242-1256, 2015 | 662 | 2015 |
Obesity shapes metabolism in the tumor microenvironment to suppress anti-tumor immunity AE Ringel, JM Drijvers, GJ Baker, A Catozzi, JC García-Cañaveras, ... Cell 183 (7), 1848-1866. e26, 2020 | 399 | 2020 |
Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade ZA Cooper, VR Juneja, PT Sage, DT Frederick, A Piris, D Mitra, JA Lo, ... Cancer immunology research 2 (7), 643-654, 2014 | 261 | 2014 |
Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity AM Paterson, SB Lovitch, PT Sage, VR Juneja, Y Lee, JD Trombley, ... Journal of Experimental Medicine 212 (10), 1603-1621, 2015 | 239 | 2015 |
Suppression by TFR cells leads to durable and selective inhibition of B cell effector function PT Sage, N Ron-Harel, VR Juneja, DR Sen, S Maleri, W Sungnak, ... Nature immunology 17 (12), 1436-1446, 2016 | 216 | 2016 |
PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance CL Tan, JR Kuchroo, PT Sage, D Liang, LM Francisco, J Buck, YR Thaker, ... Journal of Experimental Medicine 218 (1), 2021 | 185 | 2021 |
Tracking mesenchymal stem cells with iron oxide nanoparticle loaded poly (lactide-co-glycolide) microparticles C Xu, D Miranda-Nieves, JA Ankrum, ME Matthiesen, JA Phillips, I Roes, ... Nano letters 12 (8), 4131-4139, 2012 | 148 | 2012 |
BRAF inhibition is associated with increased clonality in tumor-infiltrating lymphocytes ZA Cooper, DT Frederick, VR Juneja, RJ Sullivan, DP Lawrence, A Piris, ... Oncoimmunology 2 (10), e26615, 2013 | 117 | 2013 |
Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells JM Drijvers, JE Gillis, T Muijlwijk, TH Nguyen, EF Gaudiano, IS Harris, ... Cancer immunology research 9 (2), 184-199, 2021 | 92 | 2021 |
Clonal growth of dermal papilla cells in hydrogels reveals intrinsic differences between Sox2-positive and-negative cells in vitro and in vivo RR Driskell, VR Juneja, JT Connelly, K Kretzschmar, DWM Tan, FM Watt Journal of Investigative Dermatology 132 (4), 1084-1093, 2012 | 84 | 2012 |
Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses JA Lo, M Kawakubo, VR Juneja, MY Su, TH Erlich, MW LaFleur, ... Science translational medicine 13 (581), eabd8636, 2021 | 60 | 2021 |
A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade IX Chen, K Newcomer, KE Pauken, VR Juneja, K Naxerova, MW Wu, ... Proceedings of the National Academy of Sciences 117 (38), 23684-23694, 2020 | 42 | 2020 |
Systematic discovery and validation of T cell targets directed against oncogenic KRAS mutations J Choi, SP Goulding, BP Conn, CD McGann, JL Dietze, J Kohler, ... Cell reports methods 1 (5), 2021 | 30 | 2021 |
A phase II study of combined therapy with a BRAF inhibitor (vemurafenib) and interleukin-2 (aldesleukin) in patients with metastatic melanoma MJ Mooradian, A Reuben, PA Prieto, M Hazar-Rethinam, DT Frederick, ... Oncoimmunology 7 (5), e1423172, 2018 | 24 | 2018 |
p73 expression and function in vestibular schwannoma ZK Ahmad, X Altuna, JP Lopez, Y An, J Wang-Rodriguez, VR Juneja, ... Archives of Otolaryngology–Head & Neck Surgery 135 (7), 662-669, 2009 | 9 | 2009 |
Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade. Cancer Immunol Res 2014; 2: 643-54; PMID: 24903021 ZA Cooper, VR Juneja, PT Sage, DT Frederick, A Piris, D Mitra, JA Lo, ... CIR-13-0215, 0 | 9 | |
Monitoring PD-1 phosphorylation to evaluate PD-1 signaling during antitumor immune responses X Bu, VR Juneja, CG Reynolds, KM Mahoney, MT Bu, KA McGuire, ... Cancer immunology research 9 (12), 1465-1475, 2021 | 8 | 2021 |
Neoantigens and uses thereof V Juneja US Patent App. 17/254,128, 2021 | 4 | 2021 |