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Željko M. Svedružić Ph.D.
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Cited by
Year
Mammalian cytosine DNA methyltransferase Dnmt1: enzymatic mechanism, novel mechanism-based inhibitors, and RNA-directed DNA methylation
ZM Svedruzic
Current medicinal chemistry 15 (1), 92-106, 2008
632008
Dnmt1 structure and function.
Svedružić, ŽM
Progress in molecular biology and translational science 101, 221, 2011
602011
The mechanism of target base attack in DNA cytosine carbon 5 methylation
ZM Svedruzic, NO Reich
Biochemistry 43 (36), 11460-11473, 2004
552004
DNA Cytosine C5 Methyltransferase Dnmt1:  Catalysis-Dependent Release of Allosteric Inhibition
ŽM Svedružić, NO Reich
Biochemistry 44 (27), 9472-9485, 2005
522005
Mechanism of allosteric regulation of Dnmt1's processivity
ZM Svedruzic, NO Reich
Biochemistry 44 (45), 14977-14988, 2005
412005
Modulators of γ-secretase activity can facilitate the toxic side-effects and pathogenesis of Alzheimer's disease
ŽM Svedružić, K Popović, V Šendula-Jengić
PloS one 8 (1), e50759, 2013
382013
Accommodation and repair of a UV photoproduct in DNA at different rotational settings on the nucleosome surface
ZM Svedružić, C Wang, JV Kosmoski, MJ Smerdon
Journal of Biological Chemistry 280 (48), 40051-40057, 2005
302005
Interaction between mammalian glyceraldehyde‐3‐phosphate dehydrogenase and L‐lactate dehydrogenase from heart and muscle
ŽM Svedružić, HO Spivey
Proteins: Structure, Function, and Bioinformatics 63 (3), 501-511, 2006
292006
Modulation of γ-Secretase Activity by Multiple Enzyme-Substrate Interactions: Implications in Pathogenesis of Alzheimer's Disease
ŽM Svedružić, K Popović, I Smoljan, V Šendula-Jengić
PloS one 7 (3), e32293, 2012
232012
In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1
V Miletić, I Odorčić, P Nikolić, ŽM Svedružić
PloS one 12 (4), e0174410, 2017
202017
Decrease in catalytic capacity of γ-secretase can facilitate pathogenesis in sporadic and Familial Alzheimer's disease
ŽM Svedružić, K Popović, V Šendula-Jengić
Molecular and Cellular Neuroscience 67, 55-65, 2015
162015
Pro-inflammatory S100A9 protein aggregation promoted by NCAM1 peptide constructs
J Pansieri, L Ostojić, IA Iashchishyn, M Magzoub, C Wallin, ...
ACS Chemical Biology 14 (7), 1410-1417, 2019
132019
Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase
Svedružić Ž.M., Odorčić I., Chang C.H., Svedružić D.
Scientific Reports 10 (1), 10404, 2020
10*2020
Polyoxometalates as effective nano-inhibitors of amyloid aggregation of pro-inflammatory S100A9 protein involved in neurodegenerative diseases
H Chaudhary, I Iashchyshin, N Romanova, M Rambaran, G Musteikyte, ...
ACS Applied Materials & Interfaces, 2021
82021
Natural Compound from Olive Oil Inhibits S100A9 Amyloid Formation and Cytotoxicity: Implications for Preventing Alzheimer’s Disease
Leri M, Chaudhary H, Iashchyshin IA, Pansieri J, Svedružić ŽM, Gmez Alcalde ...
ACS Chemical Neuroscience, 2021
82021
Determination of the Specific Radioactivity of [14C] Lactate by Enzymatic Decarboxylation and14CO2Collection
EA Lehoux, Z Svedruzic, HO Spivey
Analytical biochemistry 253 (2), 190-195, 1997
71997
Structural analysis of the simultaneous activation and inhibition of γ-secretase activity in the development of drugs for Alzheimer’s disease
ŽM Svedružić, K Vrbnjak, M Martinović, V Miletić
Pharmaceutics 13 (4), 514, 2021
52021
Zn(II) binding causes interdomain changes in the structure and flexibility of the human prion protein
KM Gielnik M, Taube M, Zhukova L, Zhukov I, Wärmländer S-K.T.S.*, Svedružić ...
Scientific Reports 11 (1), 2021
22021
In Silico Optimization of the First DNA-Independent Mechanism-Based Inhibitor of Mammalian DNA Methyltransferase DNMT1
P Nikolić, V Miletić, I Odorcić, ŽM Svedružić
Epi-Informatics, 113-153, 2016
22016
Binding of different substrate molecules at the docking site and the active site of γ-secretase can trigger toxic events in sporadic and familial Alzheimer's disease
ŽM Svedružić, V Šendula-Jengić, L Ostojić
biorxiv.org, 2022
2022
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Articles 1–20