Hyun Jung Kim, PhD
Hyun Jung Kim, PhD
Cleveland Clinic, Department of Inflammation and Immunity
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Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow
HJ Kim, D Huh, G Hamilton, DE Ingber
Lab Chip 12 (12), 2165-2174, 2012
Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip
HJ Kim, H Li, JJ Collins, DE Ingber
Proc. Natl. Acad. Sci. U.S.A. 113, E7-E15, 2016
Microengineered physiological biomimicry: organs-on-chips
D Huh, Y Torisawa, GA Hamilton, HJ Kim, DE Ingber
Lab on a Chip 12 (12), 2156-2164, 2012
Microfabrication of human organs-on-chips
D Huh, HJ Kim, JP Fraser, DE Shea, M Khan, A Bahinski, GA Hamilton, ...
Nature protocols 8 (11), 2135-2157, 2013
Gut-on-a-Chip Microenvironment Induces Human Intestinal Cells to Undergo Villus Differentiation
HJ Kim, D Ingber
Integr. Biol. 5, 1130-1140, 2013
Engineered In Vitro Disease Models
DEI KH Benam, S Dauth, B Hassell, A Herland, A Jain, KJ Jang, K Karalis, HJ ...
Annu. Rev. Pathol. Mech. Dis. 10, 195-262, 2015
Defined spatial structure stabilizes a synthetic multispecies bacterial community
HJ Kim, JQ Boedicker, JW Choi, RF Ismagilov
Proceedings of the National Academy of Sciences 105 (47), 18188-18193, 2008
Microfluidic organ-on-a-chip models of human intestine
A Bein, W Shin, S Jalili-Firoozinezhad, MH Park, A Sontheimer-Phelps, ...
Cellular and molecular gastroenterology and hepatology 5 (4), 659-668, 2018
Intestinal barrier dysfunction orchestrates the onset of inflammatory host–microbiome cross-talk in a human gut inflammation-on-a-chip
W Shin, HJ Kim
Proceedings of the National Academy of Sciences 115 (45), E10539-E10547, 2018
Measuring Direct Current Trans-Epithelial Electrical Resistance in Organ-on-a-Chip Microsystems
AB M Odijk, AD van der Meer, D Levner, HJ Kim, MW van der Helm, LI Segerink ...
Lab Chip 15, 745-752, 2015
Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip
S Jalili-Firoozinezhad, R Prantil-Baun, A Jiang, R Potla, T Mammoto, ...
Cell death & disease 9 (2), 223, 2018
Human intestinal morphogenesis controlled by transepithelial morphogen gradient and flow-dependent physical cues in a microengineered gut-on-a-chip
W Shin, CD Hinojosa, DE Ingber, HJ Kim
IScience 15, 391-406, 2019
A robust longitudinal co-culture of obligate anaerobic gut microbiome with human intestinal epithelium in an anoxic-oxic interface-on-a-chip
W Shin, A Wu, MW Massidda, C Foster, N Thomas, DW Lee, H Koh, Y Ju, ...
Frontiers in bioengineering and biotechnology 7, 429139, 2019
Isolation, incubation, and parallel functional testing and identification by FISH of rare microbial single-copy cells from multi-species mixtures using the combination of …
W Liu, HJ Kim, EM Lucchetta, W Du, RF Ismagilov
Lab on a Chip 9 (15), 2153-2162, 2009
Development of inhibitors against lipase and α-glucosidase from derivatives of monascus pigment
JH Kim, HJ Kim, HW Park, SH Youn, DY Choi, CS Shin
FEMS Microbiology Letters 276 (1), 93-98, 2007
The gut-brain axis in neurodegenerative diseases and relevance of the canine model: a review
YM Ambrosini, D Borcherding, A Kanthasamy, HJ Kim, AA Willette, ...
Frontiers in aging neuroscience 11, 130, 2019
Morphology control of Monascus cells and scale-up of pigment fermentation
HJ Kim, JH Kim, HJ Oh, CS Shin
Process Biochemistry 38 (5), 649-655, 2002
3D in vitro morphogenesis of human intestinal epithelium in a gut-on-a-chip or a hybrid chip with a cell culture insert
W Shin, HJ Kim
Nature Protocols 17, 910-939, 2022
Co-culture of living microbiome with microengineered human intestinal villi in a gut-on-a-chip microfluidic device
HJ Kim, J Lee, JH Choi, A Bahinski, DE Ingber
JoVE (Journal of Visualized Experiments), e54344, 2016
Development of lipase inhibitors from various derivatives of monascus pigment produced by Monascus fermentation
JH Kim, HJ Kim, C Kim, H Jung, YO Kim, JY Ju, CS Shin
Food chemistry 101 (1), 357-364, 2007
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