| A genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes SM Sidik, D Huet, SM Ganesan, MH Huynh, T Wang, AS Nasamu, P Thiru, ... Cell 166 (6), 1423-1435. e12, 2016 | 710 | 2016 |
| Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites SM Ganesan, A Falla, SJ Goldfless, AS Nasamu, JC Niles Nature communications 7 (1), 10727, 2016 | 173 | 2016 |
| Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion AS Nasamu, S Glushakova, I Russo, B Vaupel, A Oksman, AS Kim, ... Science 358 (6362), 518-522, 2017 | 167 | 2017 |
| Muscle-specific SIRT1 gain-of-function increases slow-twitch fibers and ameliorates pathophysiology in a mouse model of duchenne muscular dystrophy A Chalkiadaki, M Igarashi, AS Nasamu, J Knezevic, L Guarente PLoS genetics 10 (7), e1004490, 2014 | 152 | 2014 |
| EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX M Garten, AS Nasamu, JC Niles, J Zimmerberg, DE Goldberg, JR Beck Nature microbiology 3 (10), 1090-1098, 2018 | 120 | 2018 |
| Malaria parasite plasmepsins: More than just plain old degradative pepsins AS Nasamu, AJ Polino, ES Istvan, DE Goldberg Journal of Biological Chemistry 295 (25), 8425-8441, 2020 | 55 | 2020 |
| An integrated platform for genome engineering and gene expression perturbation in Plasmodium falciparum AS Nasamu, A Falla, CFA Pasaje, BA Wall, JC Wagner, SM Ganesan, ... Scientific reports 11 (1), 342, 2021 | 38 | 2021 |
| Rounding precedes rupture and breakdown of vacuolar membranes minutes before malaria parasite egress from erythrocytes S Glushakova, JR Beck, M Garten, BL Busse, AS Nasamu, ... Cellular microbiology 20 (10), e12868, 2018 | 38 | 2018 |
| Complex nutrient channel phenotypes despite Mendelian inheritance in a Plasmodium falciparum genetic cross A Gupta, AAB Bokhari, AD Pillai, AK Crater, J Gezelle, G Saggu, ... PLoS pathogens 16 (2), e1008363, 2020 | 33 | 2020 |
| Assessment of Biological Role and Insight into Druggability of the Plasmodium falciparum Protease Plasmepsin V AJ Polino, AS Nasamu, JC Niles, DE Goldberg ACS Infectious Diseases 6 (4), 738-746, 2020 | 32 | 2020 |
| Fast-acting small molecules targeting malarial aspartyl proteases, plasmepsins, inhibit malaria infection at multiple life stages S Singh, V Rajendran, J He, AK Singh, AO Achieng, Vandana, A Pant, ... ACS Infectious Diseases 5 (2), 184-198, 2018 | 20 | 2018 |
| 4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl-N-benzylpyrrolidine-3-carboxamides MJ Meyers, J Liu, J Xu, F Leng, J Guan, Z Liu, SA McNitt, L Qin, L Dai, ... Journal of medicinal chemistry 62 (7), 3503-3512, 2019 | 16 | 2019 |
| Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation S Bopp, CFA Pasaje, RL Summers, P Magistrado-Coxen, KA Schindler, ... Nature Communications 14 (1), 1455, 2023 | 7 | 2023 |
| GeneTargeter: Automated In Silico Design for Genome Editing in the Malaria Parasite, Plasmodium falciparum P Cárdenas, LY Esherick, G Chambonnier, S Dey, CV Turlo, AS Nasamu, ... The CRISPR Journal 5 (1), 155-164, 2022 | 5 | 2022 |
| Activation of the Plasmodium Egress Effector Subtilisin-Like Protease 1 Is Mediated by Plasmepsin X Destruction of the Prodomain S Mukherjee, AS Nasamu, KC Rubiano, DE Goldberg Mbio 14 (2), e00673-23, 2023 | 4 | 2023 |
| Exp2 in the role of the small molecule pore in the parasitophorous vacuole membrane of Plasmodium falciparum M Garten, JR Beck, S Glushakova, AS Nasamu, JC Niles, DE Goldberg, ... Biophysical Journal 114 (3), 492a, 2018 | 2 | 2018 |
| A NATURAL VARIANT IN PLASMODIUM FALCIPARUM ACYL CO-A SYNTHETASE 10 CONFERS RESISTANCE TO NOVEL ANTIMALARIALS S Bopp, C Pasaje, P Magistrado-Coxen, R Summers, VC Lopez, S Dey, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 105 (5), 61-62, 2021 | | 2021 |
| The roles of plasmepsins IX and X in malaria parasite biology AS Nasamu Washington University in St. Louis, 2021 | | 2021 |
| Fast-acting small molecules targeting malarial aspartyl proteases, plasmepsins, inhibit malaria infection at multiple life stages. SS Snigdha Singh, VR Vinoth Rajendran, JH Jiang He, AK Singh, ... | | 2019 |
| Malaria Parasites Break and Degrade Two Membranes to Egress from Human Erythrocyte SE Glushakova, J Beck, M Garten, B Busse, AS Nasamu, ... Biophysical Journal 116 (3), 218a, 2019 | | 2019 |
