Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease M Meyer-Luehmann, TL Spires-Jones, C Prada, M Garcia-Alloza, ... Nature 451 (7179), 720-724, 2008 | 1225 | 2008 |
Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model M Garcia‐Alloza, LA Borrelli, A Rozkalne, BT Hyman, BJ Bacskai Journal of neurochemistry 102 (4), 1095-1104, 2007 | 844 | 2007 |
Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease M Garcia-Alloza, EM Robbins, SX Zhang-Nunes, SM Purcell, ... Neurobiology of disease 24 (3), 516-524, 2006 | 841 | 2006 |
Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice KV Kuchibhotla, CR Lattarulo, BT Hyman, BJ Bacskai Science 323 (5918), 1211-1215, 2009 | 808 | 2009 |
Aβ plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks KV Kuchibhotla, ST Goldman, CR Lattarulo, HY Wu, BT Hyman, ... Neuron 59 (2), 214-225, 2008 | 731 | 2008 |
Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons BJ Bacskai, B Hochner, M Mahaut-Smith, SR Adams, BK Kaang, ... Science 260 (5105), 222-226, 1993 | 677 | 1993 |
Cerebral amyloid angiopathy and Alzheimer disease—one peptide, two pathways SM Greenberg, BJ Bacskai, M Hernandez-Guillamon, J Pruzin, R Sperling, ... Nature Reviews Neurology 16 (1), 30-42, 2020 | 658 | 2020 |
Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy TL Spires, M Meyer-Luehmann, EA Stern, PJ McLean, J Skoch, ... Journal of Neuroscience 25 (31), 7278-7287, 2005 | 656 | 2005 |
Caspase activation precedes and leads to tangles A De Calignon, LM Fox, R Pitstick, GA Carlson, BJ Bacskai, ... Nature 464 (7292), 1201-1204, 2010 | 652 | 2010 |
Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria P Pasinelli, ME Belford, N Lennon, BJ Bacskai, BT Hyman, D Trotti, ... Neuron 43 (1), 19-30, 2004 | 646 | 2004 |
Imaging of amyloid-β deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy BJ Bacskai, ST Kajdasz, RH Christie, C Carter, D Games, P Seubert, ... Nature medicine 7 (3), 369-372, 2001 | 636 | 2001 |
Reversible memory loss in a mouse transgenic model of Alzheimer's disease LA Kotilinek, B Bacskai, M Westerman, T Kawarabayashi, L Younkin, ... Journal of Neuroscience 22 (15), 6331-6335, 2002 | 557 | 2002 |
Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-β deposits C Ran, X Xu, SB Raymond, BJ Ferrara, K Neal, BJ Bacskai, Z Medarova, ... Journal of the American Chemical Society 131 (42), 15257-15261, 2009 | 501 | 2009 |
Emerging concepts in sporadic cerebral amyloid angiopathy A Charidimou, G Boulouis, ME Gurol, C Ayata, BJ Bacskai, MP Frosch, ... Brain 140 (7), 1829-1850, 2017 | 495 | 2017 |
A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain CA Mathis, BJ Bacskai, ST Kajdasz, ME McLellan, MP Frosch, BT Hyman, ... Bioorganic & medicinal chemistry letters 12 (3), 295-298, 2002 | 495 | 2002 |
Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing NJ Lennon, A Kho, BJ Bacskai, SL Perlmutter, BT Hyman, RH Brown Journal of Biological Chemistry 278 (50), 50466-50473, 2003 | 478 | 2003 |
Imaging Aβ plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative WE Klunk, BJ Bacskai, CA Mathis, ST Kajdasz, ME McLellan, MP Frosch, ... Journal of Neuropathology & Experimental Neurology 61 (9), 797-805, 2002 | 471 | 2002 |
Amyloid β induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation HY Wu, E Hudry, T Hashimoto, K Kuchibhotla, A Rozkalne, Z Fan, ... Journal of Neuroscience 30 (7), 2636-2649, 2010 | 430 | 2010 |
Non-Fc-mediated mechanisms are involved in clearance of amyloid-β in vivo by immunotherapy BJ Bacskai, ST Kajdasz, ME McLellan, D Games, P Seubert, D Schenk, ... Journal of Neuroscience 22 (18), 7873-7878, 2002 | 418 | 2002 |
In vivo optical imaging of amyloid aggregates in brain: design of fluorescent markers EE Nesterov, J Skoch, BT Hyman, WE Klunk, BJ Bacskai, TM Swager Angewandte Chemie International Edition 44 (34), 5452-5456, 2005 | 406 | 2005 |