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Kevin Gorski
Kevin Gorski
Verified email at amgen.com
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Year
Oncolytic virotherapy promotes intratumoral T cell infiltration and improves anti-PD-1 immunotherapy
A Ribas, R Dummer, I Puzanov, A VanderWalde, RHI Andtbacka, ...
Cell 170 (6), 1109-1119. e10, 2017
13302017
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
KS Gorski*, M Tseng*, Su-Yi, Otsuji*, X Huang, JE Slansky, SI Pai, ...
The Journal of experimental medicine 193 (7), 839-846, 2001
12032001
Effects of an anti-TSLP antibody on allergen-induced asthmatic responses
GM Gauvreau, PM O'Byrne, LP Boulet, Y Wang, D Cockcroft, J Bigler, ...
New England Journal of Medicine 370 (22), 2102-2110, 2014
8812014
Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8
KB Gorden, KS Gorski, SJ Gibson, RM Kedl, WC Kieper, X Qiu, MA Tomai, ...
The Journal of Immunology 174 (3), 1259-1268, 2005
8672005
Talimogene laherparepvec in combination with ipilimumab in previously untreated, unresectable stage IIIB-IV melanoma
I Puzanov, MM Milhem, D Minor, O Hamid, A Li, L Chen, M Chastain, ...
Journal of Clinical Oncology 34 (22), 2619-2626, 2016
5662016
Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1
AW Tolcher, J Sarantopoulos, A Patnaik, K Papadopoulos, CC Lin, ...
Journal of Clinical Oncology 27 (34), 5800-5807, 2009
4162009
Cutting edge: expression of functional CD137 receptor by dendritic cells
RA Wilcox, AI Chapoval, KS Gorski, M Otsuji, T Shin, DB Flies, K Tamada, ...
The Journal of Immunology 168 (9), 4262-4267, 2002
3412002
Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor
T Shin, G Kennedy, KS Gorski, H Tsuchiya, H Koseki, M Azuma, H Yagita, ...
The Journal of experimental medicine 198 (1), 31-38, 2003
2342003
Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists
KS Gorski, EL Waller, J Bjornton-Severson, JA Hanten, CL Riter, ...
International immunology 18 (7), 1115-1126, 2006
1932006
First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agonist, to activate innate immune responses in patients with advanced cancer
AZ Dudek, C Yunis, LI Harrison, S Kumar, R Hawkinson, S Cooley, ...
Clinical Cancer Research 13 (23), 7119-7125, 2007
1812007
Oncolytic virotherapy promotes intratumoral T cell infiltration and improves anti-PD-1 immunotherapy
A Ribas, R Dummer, I Puzanov, A VanderWalde, RHI Andtbacka, ...
Cell 174 (4), 1031-1032, 2018
1512018
Selective modulation of TLR-mediated biological activity
JR Fink, KB Gorden, KS Gorski, SK Gupta, X Qiu, JP Vasilakos
US Patent 7,485,432, 2009
1462009
Efficacy analysis of MASTERKEY-265 phase 1b study of talimogene laherparepvec (T-VEC) and pembrolizumab (pembro) for unresectable stage IIIB-IV melanoma.
GV Long, R Dummer, A Ribas, I Puzanov, A VanderWalde, ...
Journal of Clinical Oncology 34 (15_suppl), 9568-9568, 2016
1262016
Neoadjuvant talimogene laherparepvec plus surgery versus surgery alone for resectable stage IIIB–IVM1a melanoma: a randomized, open-label, phase 2 trial
R Dummer, DE Gyorki, J Hyngstrom, AC Berger, R Conry, L Demidov, ...
Nature medicine 27 (10), 1789-1796, 2021
1052021
Primary analysis of a phase 1b multicenter trial to evaluate safety and efficacy of talimogene laherparepvec (T-VEC) and ipilimumab (ipi) in previously untreated, unresected …
I Puzanov, MM Milhem, RHI Andtbacka, DR Minor, O Hamid, A Li, ...
Journal of Clinical Oncology 32 (15_suppl), 9029-9029, 2014
982014
Immunotherapy of established tumors using bone marrow transplantation with antigen gene–modified hematopoietic stem cells
Y Cui, E Kelleher, E Straley, E Fuchs, KS Gorski, H Levitsky, I Borrello, ...
Nature medicine 9 (7), 952-958, 2003
732003
B7-DC, Dendritic cell co-stimulatory molecules
DM Pardoll, H Tsuchiya, KS Gorski, SY Tseng
US Patent 7,030,219, 2006
70*2006
Homeostasis of human NK cells is not IL-15 dependent
H Lebrec, MJ Horner, KS Gorski, W Tsuji, D Xia, WJ Pan, G Means, ...
The Journal of Immunology 191 (11), 5551-5558, 2013
672013
Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors
T Doi, H Murakami, A Ohtsu, N Fuse, T Yoshino, N Yamamoto, N Boku, ...
Cancer Chemotherapy and Pharmacology 68, 733-741, 2011
652011
Talimogene laherparepvec upregulates immune-cell populations in non-injected lesions: Findings from a phase II, multicenter, open-label study in patients with stage IIIB–IVM1c …
J Malvehy, I Samoylenko, D Schadendorf, R Gutzmer, JJ Grob, JJ Sacco, ...
Journal for ImmunoTherapy of Cancer 9 (3), 2021
532021
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