Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis RC Wirka, D Wagh, DT Paik, M Pjanic, T Nguyen, CL Miller, R Kundu, ... Nature medicine 25 (8), 1280-1289, 2019 | 625 | 2019 |
Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci CL Miller, M Pjanic, T Wang, T Nguyen, A Cohain, JD Lee, L Perisic, ... Nature communications 7 (1), 12092, 2016 | 144 | 2016 |
Coronary artery disease associated transcription factor TCF21 regulates smooth muscle precursor cells that contribute to the fibrous cap ST Nurnberg, K Cheng, A Raiesdana, R Kundu, CL Miller, JB Kim, ... PLoS genetics 11 (5), e1005155, 2015 | 126 | 2015 |
Coronary Disease-Associated Gene TCF21 Inhibits Smooth Muscle Cell Differentiation by Blocking the Myocardin-Serum Response Factor Pathway M Nagao, Q Lyu, Q Zhao, RC Wirka, J Bagga, T Nguyen, P Cheng, JB Kim, ... Circulation research 126 (4), 517-529, 2020 | 93 | 2020 |
Genetic regulatory mechanisms of smooth muscle cells map to coronary artery disease risk loci B Liu, M Pjanic, T Wang, T Nguyen, M Gloudemans, A Rao, VG Castano, ... The American Journal of Human Genetics 103 (3), 377-388, 2018 | 89 | 2018 |
Environment-sensing aryl hydrocarbon receptor inhibits the chondrogenic fate of modulated smooth muscle cells in atherosclerotic lesions JB Kim, Q Zhao, T Nguyen, M Pjanic, P Cheng, R Wirka, S Travisano, ... Circulation 142 (6), 575-590, 2020 | 69 | 2020 |
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth … JB Kim, M Pjanic, T Nguyen, CL Miller, D Iyer, B Liu, T Wang, O Sazonova, ... PLoS Genetics 13 (5), e1006750, 2017 | 66 | 2017 |
Nuclear factor I revealed as family of promoter binding transcription activators M Pjanic, P Pjanic, C Schmid, G Ambrosini, A Gaussin, G Plasari, ... BMC genomics 12, 1-10, 2011 | 61 | 2011 |
Characterization of TCF21 downstream target regions identifies a transcriptional network linking multiple independent coronary artery disease loci O Sazonova, Y Zhao, S Nürnberg, C Miller, M Pjanic, VG Castano, JB Kim, ... PLoS genetics 11 (5), e1005202, 2015 | 56 | 2015 |
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk D Iyer, Q Zhao, R Wirka, A Naravane, T Nguyen, B Liu, M Nagao, ... PLoS genetics 14 (10), e1007681, 2018 | 55 | 2018 |
TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression Q Zhao, R Wirka, T Nguyen, M Nagao, P Cheng, CL Miller, JB Kim, ... Genome medicine 11, 1-18, 2019 | 53 | 2019 |
The role of polycarbonate monomer bisphenol-A in insulin resistance M Pjanic PeerJ 5, e3809, 2017 | 53 | 2017 |
Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases ST Nurnberg, MA Guerraty, RC Wirka, HS Rao, M Pjanic, S Norton, ... PLoS Genetics 16 (1), e1008538, 2020 | 46 | 2020 |
Genetics and genomics of coronary artery disease M Pjanic, CL Miller, R Wirka, JB Kim, DM DiRenzo, T Quertermous Current cardiology reports 18, 1-10, 2016 | 46 | 2016 |
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus V Nanda, T Wang, M Pjanic, B Liu, T Nguyen, LP Matic, U Hedin, ... PLoS genetics 14 (11), e1007755, 2018 | 42 | 2018 |
Advances in transcriptomics: investigating cardiovascular disease at unprecedented resolution RC Wirka, M Pjanic, T Quertermous Circulation research 122 (9), 1200-1220, 2018 | 40 | 2018 |
Nuclear Factor I genomic binding associates with chromatin boundaries M Pjanic, CD Schmid, A Gaussin, G Ambrosini, J Adamcik, P Pjanic, ... BMC genomics 14, 1-18, 2013 | 38 | 2013 |
Molecular characterization of a human matrix attachment region epigenetic regulator S Arope, N Harraghy, M Pjanic, N Mermod PLoS One 8 (11), e79262, 2013 | 38 | 2013 |
Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping Q Zhao, M Dacre, T Nguyen, M Pjanic, B Liu, D Iyer, P Cheng, R Wirka, ... Genome biology 21, 1-23, 2020 | 22 | 2020 |
From locus association to mechanism of gene causality: the devil is in the details CL Miller, M Pjanic, T Quertermous Arteriosclerosis, thrombosis, and vascular biology 35 (10), 2079-2080, 2015 | 14 | 2015 |