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Maria Pires Pacheco
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Year
Fast reconstruction of compact context-specific metabolic network models
N Vlassis, MP Pacheco, T Sauter
PLoS computational biology 10 (1), e1003424, 2014
2572014
The gut microbial metabolite formate exacerbates colorectal cancer progression
D Ternes, M Tsenkova, VI Pozdeev, M Meyers, E Koncina, S Atatri, ...
Nature metabolism 4 (4), 458-475, 2022
1112022
Integrated in vitro and in silico modeling delineates the molecular effects of a synbiotic regimen on colorectal-cancer-derived cells
G Kacy, RG Javier, H Almut, U Pit, B Tamara, P Maria Pires, J Baginska, ...
Cell reports, 2019
72*2019
Identifying and targeting cancer-specific metabolism with network-based drug target prediction
MP Pacheco, T Bintener, D Ternes, D Kulms, S Haan, E Letellier, T Sauter
EBioMedicine 43, 98-106, 2019
642019
Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network
MP Pacheco, E John, T Kaoma, M Heinäniemi, N Nicot, L Vallar, JL Bueb, ...
BMC genomics 16 (1), 809, 2015
512015
Loss of Ambra1 promotes melanoma growth and invasion
L Di Leo, V Bodemeyer, FM Bosisio, G Claps, M Carretta, S Rizza, ...
Nature communications 12 (1), 2550, 2021
372021
Benchmarking procedures for high-throughput context specific reconstruction algorithms
M Pires Pacheco, T Pfau, T Sauter
Frontiers in Physiology 6, 410, 2016
36*2016
The power of LC-MS based multiomics: exploring adipogenic differentiation of human mesenchymal stem/stromal cells
E Rampler, D Egger, H Schoeny, M Rusz, MP Pacheco, G Marino, ...
Molecules 24 (19), 3615, 2019
272019
The neural stem cell fate determinant TRIM32 regulates complex behavioral traits
AL Hillje, E Beckmann, MAS Pavlou, C Jaeger, MP Pacheco, T Sauter, ...
Frontiers in Cellular Neuroscience 9, 75, 2015
242015
Towards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyond
T Pfau, MP Pacheco, T Sauter
Briefings in Bioinformatics 17 (6), 1060-1069, 2016
222016
DCcov: Repositioning of drugs and drug combinations for SARS-CoV-2 infected lung through constraint-based modeling
A Kishk, MP Pacheco, T Sauter
Iscience 24 (11), 2021
162021
Towards the routine use of in silico screenings for drug discovery using metabolic modelling
T Bintener, MP Pacheco, T Sauter
Biochemical Society Transactions 48 (3), 955-969, 2020
152020
The FASTCORE family: For the fast reconstruction of compact context-specific metabolic networks models
MP Pacheco, T Sauter
Metabolic Network Reconstruction and Modeling: Methods and Protocols, 101-110, 2018
132018
A dynamic multi-tissue model to study human metabolism
P Martins Conde, T Pfau, M Pires Pacheco, T Sauter
NPJ systems biology and applications 7 (1), 5, 2021
122021
Importance of the biomass formulation for cancer metabolic modeling and drug prediction
MM García, M Pacheco, T Bintener, L Presta, T Sauter
Iscience 24 (10), 2021
102021
Towards the network-based prediction of repurposed drugs using patient-specific metabolic models
MP Pacheco, T Bintener, T Sauter
EBioMedicine 43, 26-27, 2019
82019
Project-based learning course on metabolic network modelling in computational systems biology
T Sauter, T Bintener, A Kishk, L Presta, T Prohaska, D Guignard, N Zeng, ...
PLoS computational biology 18 (1), e1009711, 2022
52022
Bruceine D identified as a drug candidate against breast cancer by a novel drug selection pipeline and cell viability assay
C Cipriani, MP Pacheco, A Kishk, M Wachich, D Abankwa, ...
Pharmaceuticals 15 (2), 179, 2022
42022
Review of Current Human Genome-Scale Metabolic Models for Brain Cancer and Neurodegenerative Diseases
A Kishk, MP Pacheco, T Heurtaux, L Sinkkonen, J Pang, S Fritah, ...
Cells 11 (16), 2486, 2022
32022
Fast reconstruction of compact context-specific metabolic networks via integration of microarray data
MP Pacheco, T Sauter
arXiv preprint arXiv:1407.6534, 2014
32014
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Articles 1–20