Phosphoproteomic quantitation and causal analysis reveal pathways in GPVI/ITAM-mediated platelet activation programs Ö Babur, AR Melrose, JM Cunliffe, J Klimek, J Pang, ALI Sepp, ... Blood, The Journal of the American Society of Hematology 136 (20), 2346-2358, 2020 | 70 | 2020 |
Assessment of the effects of Syk and BTK inhibitors on GPVI-mediated platelet signaling and function TJ Zheng, ER Lofurno, AR Melrose, HHS Lakshmanan, J Pang, ... American Journal of Physiology-Cell Physiology 320 (5), C902-C915, 2021 | 32 | 2021 |
Revised model of the tissue factor pathway of thrombin generation: role of the feedback activation of FXI HHS Lakshmanan, A Estonilo, SE Reitsma, AR Melrose, J Subramanian, ... Journal of Thrombosis and Haemostasis 20 (6), 1350-1363, 2022 | 17 | 2022 |
Janus kinase inhibitors ruxolitinib and baricitinib impair glycoprotein-VI mediated platelet function I Parra-Izquierdo, AR Melrose, J Pang, HHS Lakshmanan, SE Reitsma, ... Platelets 33 (3), 404-415, 2022 | 17 | 2022 |
Effects of ex vivo blood anticoagulation and preanalytical processing time on the proteome content of platelets ST Yunga, AJ Gower, AR Melrose, MK Fitzgerald, A Rajendran, ... Journal of Thrombosis and Haemostasis 20 (6), 1437-1450, 2022 | 15 | 2022 |
The toll-like receptor 2 ligand Pam2CSK4 activates platelet nuclear factor-κB and Bruton’s tyrosine kinase signaling to promote platelet-endothelial cell interactions I Parra-Izquierdo, HHS Lakshmanan, AR Melrose, J Pang, TJ Zheng, ... Frontiers in immunology 12, 729951, 2021 | 14 | 2021 |
The basement membrane protein nidogen-1 supports platelet adhesion and activation HHS Lakshmanan, AR Melrose, ALI Sepp, A Mitrugno, ATP Ngo, ... Platelets 32 (3), 424-428, 2021 | 10 | 2021 |
Effect of antiplatelet agents and tyrosine kinase inhibitors on oxLDL-mediated procoagulant platelet activity TJ Zheng, TCL Kohs, PA Mueller, J Pang, SE Reitsma, I Parra-Izquierdo, ... Blood Advances 7 (8), 1366-1378, 2023 | 7 | 2023 |
Platelet reactivity and platelet count in women with iron deficiency treated with intravenous iron BK Elstrott, HHS Lakshmanan, AR Melrose, KR Jordan, KL Martens, ... Research and Practice in Thrombosis and Haemostasis 6 (2), e12692, 2022 | 7 | 2022 |
Identification, Quantification, and System Analysis of Protein N‐ε Lysine Methylation in Anucleate Blood Platelets AD Rocheleau, AR Melrose, JM Cunliffe, J Klimek, Ö Babur, ... Proteomics 19 (11), 1900001, 2019 | 7 | 2019 |
Tyrosine Kinase Inhibitors (TKIs) Targeting Syk and BTK Signaling Differentially Affect PI3K Signalosome Organization and Platelet Function T Zheng, ER Lofurno, S Elgamal, AR Melrose, J Pang, JJ Shatzel, ... Blood 134, 2074, 2019 | 1 | 2019 |
PB0885 β-amyloid Peptide Aβ40 Stimulates Glycoprotein Receptor GPVI Signaling to Generate Procoagulant Platelets Y Zhang, A Melrose, J Pang, O McCarty, J Aslan Research and Practice in Thrombosis and Haemostasis 7, 101622, 2023 | | 2023 |
PB0883 Defining the Role of Hepcidin and Ferroportin Interactions in Regulating Platelet Function K Martens, A Melrose, C Yang, M Geffert, J Lo, J Shatzel, J Aslan Research and Practice in Thrombosis and Haemostasis 7, 101620, 2023 | | 2023 |
PB0421 Phosphoproteomics and Systems Analysis Reveal Protein Kinase C Theta (PKCfɵ) Signaling Events Associated with the Generation of Procoagulant Platelets Y Zhang, S Reitsma, O Babur, A Melrose, J Pang, S Hodapp, A Newton, ... Research and Practice in Thrombosis and Haemostasis 7, 101670, 2023 | | 2023 |
Protein Kinase C Theta (PKCθ) Signaling Associated With The Generation Of Procoagulant Platelets Revealed By Phosphoproteomics And Systems Analysis Y Zheng, S Reitsma, O Babur, A Melrose, J Pang, S Hodapp, A Newton, ... Arteriosclerosis, Thrombosis, and Vascular Biology 43 (Suppl_1), A123-A123, 2023 | | 2023 |
Effect Of Antiplatelet Agents And Tyrosine Kinase Inhibitors On OxLDL-mediated Platelet Procoagulant Activity TJ Zheng, J Pang, T Kohs, S Reitsma, I Parra-Izquierdo, A Melrose, ... Arteriosclerosis, Thrombosis, and Vascular Biology 42 (Suppl_1), A159-A159, 2022 | | 2022 |
Quantitative Phosphoproteomics And Causal Analysis Reveal Distinct And Combinatorial Signaling Mechanisms In Protease-Activated Receptor PAR1 And PAR4 Platelet Activation Programs S Reitsma, J Klimek, I Parra-Izquierdo, O Babur, A Melrose, T Zheng, ... Arteriosclerosis, Thrombosis, and Vascular Biology 41 (Suppl_1), A108-A108, 2021 | | 2021 |
Phosphoproteomic Profiling and Causal Pathway Mapping Reveal Signaling Relations in GPVI/ITAM-mediated Platelet Activation Programs O Babur, A Melrose, OJ McCarty, P Wilmarth, J Aslan Arteriosclerosis, Thrombosis, and Vascular Biology 40 (Suppl_1), A137-A137, 2020 | | 2020 |
Quantitative Phosphoproteomic Profiling and Causality Pathway Mapping the Platelet Response to Vascular Injury Ö Babur, A Melrose, J Cunliffe, AL Sepp, AT Ngo, O McCarty, J Klimek, ... Arteriosclerosis, Thrombosis, and Vascular Biology 39 (Suppl_1), A156-A156, 2019 | | 2019 |