| Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells AK Shalek, JT Robinson, ES Karp, JS Lee, DR Ahn, MH Yoon, A Sutton, ... Proceedings of the National Academy of Sciences 107 (5), 1870-1875, 2010 | 629 | 2010 |
| A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis TS Gujral, M Chan, L Peshkin, PK Sorger, MW Kirschner, G MacBeath Cell 159 (4), 844-856, 2014 | 362 | 2014 |
| Molecular mechanisms of RET receptor–mediated oncogenesis in Multiple Endocrine Neoplasia 2B TS Gujral, VK Singh, Z Jia, LM Mulligan Cancer research 66 (22), 10741-10749, 2006 | 112 | 2006 |
| Exploiting polypharmacology for drug target deconvolution TS Gujral, L Peshkin, MW Kirschner Proc Natl Acad Sci U S A 111 (13), 5048-5, 2014 | 104 | 2014 |
| A novel RET kinase–β-catenin signaling pathway contributes to tumorigenesis in thyroid carcinoma TS Gujral, W Van Veelen, DS Richardson, SM Myers, JA Meens, ... Cancer Research 68 (5), 1338-1346, 2008 | 93 | 2008 |
| Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays TS Gujral, RL Karp, A Finski, M Chan, PE Schwartz, G MacBeath, ... Oncogene 32 (29), 3470-3476, 2013 | 83 | 2013 |
| Hippo pathway mediates resistance to cytotoxic drugs TS Gujral, MW Kirschner Proceedings of the National Academy of Sciences 114 (18), E3729-E3738, 2017 | 77 | 2017 |
| A system-wide investigation of the dynamics of Wnt signaling reveals novel phases of transcriptional regulation TS Gujral, G MacBeath PloS one 5 (4), e10024, 2010 | 63 | 2010 |
| Organotypic tumor slice cultures provide a versatile platform for immuno-oncology and drug discovery R Sivakumar, M Chan, J Shin, N Nishida-Aoki, H Kenerson, ... OncoImmunology, 1670019, 2019 | 62 | 2019 |
| Transcript level modulates the inherent oncogenicity of RET/PTC oncoproteins DS Richardson, TS Gujral, S Peng, SL Asa, LM Mulligan Cancer research 69 (11), 4861-4869, 2009 | 61 | 2009 |
| Emerging approaches to study cell–cell interactions in tumor microenvironment N Nishida-Aoki, TS Gujral Oncotarget 10 (7), 785, 2019 | 59 | 2019 |
| A systematic family-wide investigation reveals that∼ 30% of mammalian PDZ domains engage in PDZ-PDZ interactions BH Chang, TS Gujral, ES Karp, R BuKhalid, VP Grantcharova, ... Chemistry & biology 18 (9), 1143-1152, 2011 | 59 | 2011 |
| Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases KM Sullivan, X Jiang, P Guha, C Lausted, JA Carter, C Hsu, KP Labadie, ... Gut 72 (2), 325-337, 2023 | 56 | 2023 |
| Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis F Szulzewsky, S Arora, P Hoellerbauer, C King, E Nathan, M Chan, ... Genes & development 34 (15-16), 1051-1064, 2020 | 54 | 2020 |
| RET-mediated cell adhesion and migration require multiple integrin subunits JG Cockburn, DS Richardson, TS Gujral, LM Mulligan The Journal of Clinical Endocrinology & Metabolism 95 (11), E342-E346, 2010 | 49 | 2010 |
| RET signaling in endocrine tumors: delving deeper into molecular mechanisms AZ Lai, TS Gujral, LM Mulligan Endocrine Pathology 18, 57-67, 2007 | 43 | 2007 |
| Family-wide investigation of PDZ domain-mediated protein-protein interactions implicates β-catenin in maintaining the integrity of tight junctions TS Gujral, ES Karp, M Chan, BH Chang, G MacBeath Chemistry & biology 20 (6), 816-827, 2013 | 40 | 2013 |
| Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates HHH Susman MW, Karuna EP, Kunz RC, Gujral TS, Cantú AV, Choi SS, Jong BY ... Elife 26509, 2017 | 38 | 2017 |
| Pharmaceutical compositions comprising RET inhibitors and methods for the treatment of cancer TS Gujral, LM Mulligan, VK Singh US Patent 8,629,135, 2014 | 37 | 2014 |
| Microdissected “cuboids” for microfluidic drug testing of intact tissues LF Horowitz, AD Rodriguez, A Au-Yeung, KW Bishop, LA Barner, ... Lab on a Chip 21 (1), 122-142, 2021 | 36 | 2021 |
Lois MulliganCancer Research Institute, Queen's UniversityVerified email at queensu.ca
