|Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment|
H Yu, M Kortylewski, D Pardoll
Nature Reviews Immunology 7 (1), 41-51, 2007
|Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells|
T Wang, G Niu, M Kortylewski, L Burdelya, K Shain, S Zhang, ...
Nature medicine 10 (1), 48-54, 2004
|Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity|
M Kortylewski, M Kujawski, T Wang, S Wei, S Zhang, S Pilon-Thomas, ...
Nature medicine 11 (12), 1314-1321, 2005
|IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway|
L Wang, T Yi, M Kortylewski, DM Pardoll, D Zeng, H Yu
Journal of experimental medicine 206 (7), 1457-1464, 2009
|Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways|
Q Xu, J Briggs, S Park, G Niu, M Kortylewski, S Zhang, T Gritsko, ...
Oncogene 24 (36), 5552-5560, 2005
|Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity|
TJ Harris, JF Grosso, HR Yen, H Xin, M Kortylewski, E Albesiano, ...
The Journal of Immunology 179 (7), 4313-4317, 2007
|Stat3 mediates myeloid cell–dependent tumor angiogenesis in mice|
M Kujawski, M Kortylewski, H Lee, A Herrmann, H Kay, H Yu
The Journal of clinical investigation 118 (10), 3367-3377, 2008
|Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment|
M Kortylewski, H Xin, M Kujawski, H Lee, Y Liu, T Harris, C Drake, ...
Cancer cell 15 (2), 114-123, 2009
|In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses|
M Kortylewski, P Swiderski, A Herrmann, L Wang, C Kowolik, M Kujawski, ...
Nature biotechnology 27 (10), 925-932, 2009
|STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors|
H Lee, J Deng, M Kujawski, C Yang, Y Liu, A Herrmann, M Kortylewski, ...
Nature medicine 16 (12), 1421-1428, 2010
|Targeting STAT3 affects melanoma on multiple fronts|
M Kortylewski, R Jove, H Yu
Cancer and Metastasis Reviews 24 (2), 315-327, 2005
|Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB|
A Chow, W Zhou, L Liu, MY Fong, J Champer, D Van Haute, AR Chin, ...
Scientific reports 4 (1), 1-11, 2014
|Role of Stat3 in suppressing anti-tumor immunity|
M Kortylewski, H Yu
Current opinion in immunology 20 (2), 228-233, 2008
|Signal transducer and activator of transcription 3 is required for hypoxia-inducible factor-1α RNA expression in both tumor cells and tumor-associated myeloid cells|
G Niu, J Briggs, J Deng, Y Ma, H Lee, M Kortylewski, M Kujawski, H Kay, ...
Molecular Cancer Research 6 (7), 1099-1105, 2008
|Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects|
L Burdelya, M Kujawski, G Niu, B Zhong, T Wang, S Zhang, M Kortylewski, ...
The Journal of Immunology 174 (7), 3925-3931, 2005
|Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1|
M Kortylewski, PC Heinrich, A Mackiewicz, U Schniertshauer, ...
Oncogene 18 (25), 3742-3753, 1999
|Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice|
L Zhang, D Alizadeh, M Van Handel, M Kortylewski, H Yu, B Badie
Glia 57 (13), 1458-1467, 2009
|Toll-like receptor 9 activation of signal transducer and activator of transcription 3 constrains its agonist-based immunotherapy|
M Kortylewski, M Kujawski, A Herrmann, C Yang, L Wang, Y Liu, ...
Cancer research 69 (6), 2497-2505, 2009
|Stat3 as a potential target for cancer immunotherapy|
M Kortylewski, H Yu
Journal of immunotherapy 30 (2), 131-139, 2007
|TLR9-targeted STAT3 silencing abrogates immunosuppressive activity of myeloid-derived suppressor cells from prostate cancer patients|
DMS Hossain, SK Pal, D Moreira, P Duttagupta, Q Zhang, H Won, J Jones, ...
Clinical Cancer Research 21 (16), 3771-3782, 2015