Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma L De Mattos-Arruda, R Mayor, CKY Ng, B Weigelt, F Martínez-Ricarte, ... Nature communications 6 (1), 8839, 2015 | 746 | 2015 |
PMUT: a web-based tool for the annotation of pathological mutations on proteins C Ferrer-Costa, JL Gelpí, L Zamakola, I Parraga, X De La Cruz, M Orozco Bioinformatics 21 (14), 3176-3178, 2005 | 557 | 2005 |
Do protein motifs read the histone code? X De La Cruz, S Lois, S Sánchez‐Molina, MA Martínez‐Balbás Bioessays 27 (2), 164-175, 2005 | 371 | 2005 |
Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties C Ferrer-Costa, M Orozco, X de la Cruz Journal of molecular biology 315 (4), 771-786, 2002 | 266 | 2002 |
PMut: a web-based tool for the annotation of pathological variants on proteins, 2017 update V López-Ferrando, A Gazzo, X De La Cruz, M Orozco, JL Gelpí Nucleic acids research 45 (W1), W222-W228, 2017 | 242 | 2017 |
Sequence‐based prediction of pathological mutations C Ferrer‐Costa, M Orozco, X De La Cruz Proteins: Structure, Function, and Bioinformatics 57 (4), 811-819, 2004 | 214 | 2004 |
Triplex‐forming oligonucleotide target sequences in the human genome JR Goñi, X de la Cruz, M Orozco Nucleic acids research 32 (1), 354-360, 2004 | 207 | 2004 |
Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program C Estarás, N Akizu, A García, S Beltrán, X de la Cruz, MA Martínez-Balbás Development 139 (15), 2681-2691, 2012 | 124 | 2012 |
Classical molecular interaction potentials: improved setup procedure in molecular dynamics simulations of proteins JL Gelpí, SG Kalko, X Barril, J Cirera, X de la Cruz, FJ Luque, M Orozco Proteins: Structure, Function, and Bioinformatics 45 (4), 428-437, 2001 | 107 | 2001 |
Autoacetylation regulates P/CAF nuclear localization N Blanco-García, E Asensio-Juan, X de la Cruz, MA Martínez-Balbás Journal of Biological Chemistry 284 (3), 1343-1352, 2009 | 90 | 2009 |
Scoring by intermolecular pairwise propensities of exposed residues (SIPPER): a new efficient potential for protein− protein docking C Pons, D Talavera, X De La Cruz, M Orozco, J Fernandez-Recio Journal of chemical information and modeling 51 (2), 370-377, 2011 | 79 | 2011 |
The (in) dependence of alternative splicing and gene duplication D Talavera, C Vogel, M Orozco, SA Teichmann, X De La Cruz PLoS computational biology 3 (3), e33, 2007 | 78 | 2007 |
Exploring the essential dynamics of B-DNA A Pérez, JR Blas, M Rueda, JM López-Bes, X de la Cruz, M Orozco Journal of Chemical Theory and Computation 1 (5), 790-800, 2005 | 69 | 2005 |
Characterization of compensated mutations in terms of structural and physico-chemical properties C Ferrer-Costa, M Orozco, X de la Cruz Journal of Molecular Biology 365 (1), 249-256, 2007 | 61 | 2007 |
Ligand-induced changes in the binding sites of proteins X Fradera, X De La Cruz, CHTP Silva, JL Gelpí, FJ Luque, M Orozco Bioinformatics 18 (7), 939-948, 2002 | 58 | 2002 |
An atomistic view to the gas phase proteome T Meyer, X de la Cruz, M Orozco Structure 17 (1), 88-95, 2009 | 54 | 2009 |
PupasView: a visual tool for selecting suitable SNPs, with putative pathological effect in genes, for genotyping purposes L Conde, JM Vaquerizas, C Ferrer-Costa, X de la Cruz, M Orozco, ... Nucleic acids research 33 (suppl_2), W501-W505, 2005 | 53 | 2005 |
Histone H3.3 beyond cancer: Germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients L Bryant, D Li, SG Cox, D Marchione, EF Joiner, K Wilson, K Janssen, ... Science advances 6 (49), eabc9207, 2020 | 52 | 2020 |
Epigenetic signature for attention-deficit/hyperactivity disorder: identification of miR-26b-5p, miR-185-5p, and miR-191-5p as potential biomarkers in peripheral blood … C Sánchez-Mora, M Soler Artigas, I Garcia-Martínez, M Pagerols, ... Neuropsychopharmacology 44 (5), 890-897, 2019 | 48 | 2019 |
The complementarity between protein‐specific and general pathogenicity predictors for amino acid substitutions C Riera, N Padilla, X de la Cruz Human mutation 37 (10), 1013-1024, 2016 | 48 | 2016 |