Delphine Merino
Delphine Merino
Olivia Newton-John Cancer Research Institute
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Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2
D Mérino, N Lalaoui, A Morizot, P Schneider, E Solary, O Micheau
Molecular and cellular biology 26 (19), 7046-7055, 2006
Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer
F Vaillant, D Merino, L Lee, K Breslin, B Pal, ME Ritchie, GK Smyth, ...
Cancer cell 24 (1), 120-129, 2013
The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins
D Mérino, M Giam, PD Hughes, OM Siggs, K Heger, LA O'Reilly, ...
Journal of Cell Biology 186 (3), 355-362, 2009
Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells
D Mérino, SL Khaw, SP Glaser, DJ Anderson, LD Belmont, C Wong, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5807-5816, 2012
TRAIL in cancer therapy: present and future challenges
D Mérino, N Lalaoui, A Morizot, E Solary, O Micheau
Expert opinion on therapeutic targets 11 (10), 1299-1314, 2007
A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma
O Ndozangue-Touriguine, M Sebbagh, D Merino, O Micheau, J Bertoglio, ...
Oncogene 27 (46), 6012-6022, 2008
Arsenic trioxide induces apoptosis of human monocytes during macrophagic differentiation through nuclear factor-κB-related survival pathway down-regulation
A Lemarie, C Morzadec, D Mérino, O Micheau, O Fardel, L Vernhet
Journal of Pharmacology and Experimental Therapeutics 316 (1), 304-314, 2006
Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level
A Morizot, D Mérino, N Lalaoui, G Jacquemin, V Granci, E Iessi, ...
Cell Death & Differentiation 18 (4), 700-711, 2011
TRAIL-R4 promotes tumor growth and resistance to apoptosis in cervical carcinoma HeLa cells through AKT
N Lalaoui, A Morlé, D Mérino, G Jacquemin, E Iessi, A Morizot, S Shirley, ...
PloS one 6 (5), 2011
Targeting BCL-2 to enhance vulnerability to therapy in estrogen receptor-positive breast cancer
D Merino, SW Lok, JE Visvader, GJ Lindeman
Oncogene 35 (15), 1877-1887, 2016
TRAIL induces receptor-interacting protein 1–dependent and caspase-dependent necrosis-like cell death under acidic extracellular conditions
O Meurette, A Rebillard, L Huc, G Le Moigne, D Merino, O Micheau, ...
Cancer research 67 (1), 218-226, 2007
Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer
D Merino, JR Whittle, F Vaillant, A Serrano, JN Gong, G Giner, ...
Science translational medicine 9 (401), eaam7049, 2017
Both leukaemic and normal peripheral B lymphoid cells are highly sensitive to the selective pharmacological inhibition of prosurvival Bcl-2 with ABT-199
SL Khaw, D Merino, MA Anderson, SP Glaser, P Bouillet, AW Roberts, ...
Leukemia 28 (6), 1207-1215, 2014
BH3-mimetic drugs: blazing the trail for new cancer medicines
D Merino, GL Kelly, G Lessene, AH Wei, AW Roberts, A Strasser
Cancer Cell 34 (6), 879-891, 2018
Apoptotic, necrotic, or fused tumor cells: an equivalent source of antigen for dendritic cell loading
N Larmonier, D Mérino, A Nicolas, D Cathelin, A Besson, A Bateman, ...
Apoptosis 11 (9), 1513-1524, 2006
A hypermutator phenotype attenuates the virulence of Listeria monocytogenes in a mouse model
D Mérino, H Réglier‐Poupet, P Berche, ...
Molecular microbiology 44 (3), 877-887, 2002
Predicting improvement in stroke patients referred for inpatient rehabilitation.
J Jimenez, PP Morgan
Canadian Medical Association Journal 121 (11), 1481, 1979
The inhibition of TNF-α anti-tumoral properties by blocking antibodies promotes tumor growth in a rat model
N Larmonier, D Cathelin, C Larmonier, A Nicolas, D Merino, ...
Experimental cell research 313 (11), 2345-2355, 2007
The Bcl-2 family in autoimmune and degenerative disorders
D Mérino, P Bouillet
Apoptosis 14 (4), 570, 2009
Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells
E Naik, LA O'Reilly, ML Asselin-Labat, D Merino, A Lin, M Cook, L Coultas, ...
Journal of Experimental Medicine 208 (7), 1351-1358, 2011
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