Dmitry Veprintsev
Dmitry Veprintsev
Professor of Molecular and Cellular Pharmacology, University of Nottingham
Potvrđena adresa e-pošte na - Početna stranica
Targeted rescue of a destabilized mutant of p53 by an in silico screened drug
FM Boeckler, AC Joerger, G Jaggi, TJ Rutherford, DB Veprintsev, ...
Proceedings of the National Academy of Sciences 105 (30), 10360-10365, 2008
Universal allosteric mechanism for Gα activation by GPCRs
T Flock, CNJ Ravarani, D Sun, AJ Venkatakrishnan, M Kayikci, CG Tate, ...
Nature 524 (7564), 173-179, 2015
Structures of SAS-6 suggest its organization in centrioles
M van Breugel, M Hirono, A Andreeva, H Yanagisawa, S Yamaguchi, ...
Science 331 (6021), 1196-1199, 2011
A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants
A Friedler, LO Hansson, DB Veprintsev, SMV Freund, TM Rippin, ...
Proceedings of the National Academy of Sciences 99 (2), 937-942, 2002
Hsp90-Tau complex reveals molecular basis for specificity in chaperone action
GE Karagöz, AMS Duarte, E Akoury, H Ippel, J Biernat, TM Luengo, ...
Cell 156 (5), 963-974, 2014
Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
AJ Venkatakrishnan, X Deupi, G Lebon, FM Heydenreich, T Flock, ...
Nature 536 (7617), 484-487, 2016
Cooperative binding of tetrameric p53 to DNA
RL Weinberg, DB Veprintsev, AR Fersht
Journal of molecular biology 341 (5), 1145-1159, 2004
ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes
H Teo, DJ Gill, J Sun, O Perisic, DB Veprintsev, Y Vallis, SD Emr, ...
Cell 125 (1), 99-111, 2006
Comparative binding of p53 to its promoter and DNA recognition elements
RL Weinberg, DB Veprintsev, M Bycroft, AR Fersht
Journal of molecular biology 348 (3), 589-596, 2005
Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium
Z Hayouka, J Rosenbluh, A Levin, S Loya, M Lebendiker, D Veprintsev, ...
Proceedings of the National Academy of Sciences 104 (20), 8316-8321, 2007
Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor
MR Fernandez-Fernandez, DB Veprintsev, AR Fersht
Proceedings of the National Academy of Sciences 102 (13), 4735-4740, 2005
The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger
S Eustermann, H Videler, JC Yang, PT Cole, D Gruszka, D Veprintsev, ...
Journal of molecular biology 407 (1), 149-170, 2011
Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations
AC Joerger, HC Ang, DB Veprintsev, CM Blair, AR Fersht
Journal of Biological Chemistry 280 (16), 16030-16037, 2005
Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor
S Isogai, X Deupi, C Opitz, FM Heydenreich, CJ Tsai, F Brueckner, ...
Nature 530 (7589), 237-241, 2016
Structural insight into the ESCRT‐I/‐II link and its role in MVB trafficking
DJ Gill, H Teo, J Sun, O Perisic, DB Veprintsev, SD Emr, RL Williams
The EMBO journal 26 (2), 600-612, 2007
The central region of HDM2 provides a second binding site for p53
GW Yu, S Rudiger, D Veprintsev, S Freund, MR Fernandez-Fernandez, ...
Proceedings of the National Academy of Sciences 103 (5), 1227-1232, 2006
Kinetic instability of p53 core domain mutants: implications for rescue by small molecules
A Friedler, DB Veprintsev, LO Hansson, AR Fersht
Journal of Biological Chemistry 278 (26), 24108-24112, 2003
Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24
S Ghazi-Tabatabai, S Saksena, JM Short, AV Pobbati, DB Veprintsev, ...
Structure 16 (9), 1345-1356, 2008
Structural evolution of p53, p63, and p73: implication for heterotetramer formation
AC Joerger, S Rajagopalan, E Natan, DB Veprintsev, CV Robinson, ...
Proceedings of the National Academy of Sciences 106 (42), 17705-17710, 2009
Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus
B Panic, O Perisic, DB Veprintsev, RL Williams, S Munro
Molecular cell 12 (4), 863-874, 2003
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