Louis Vermeulen MD PhD
Louis Vermeulen MD PhD
Professor Molecular Oncology - Amsterdam University Medical Centers, University of Amsterdam
Potvrđena adresa e-pošte na - Početna stranica
The consensus molecular subtypes of colorectal cancer
J Guinney, R Dienstmann, X Wang, A De Reynies, A Schlicker, ...
Nature medicine 21 (11), 1350-1356, 2015
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
L Vermeulen, F De Sousa E Melo, M Van Der Heijden, K Cameron, ...
Nature cell biology 12 (5), 468-476, 2010
Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4
M Todaro, MP Alea, AB Di Stefano, P Cammareri, L Vermeulen, F Iovino, ...
Cell stem cell 1 (4), 389-402, 2007
Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
L Vermeulen, M Todaro, F de Sousa Mello, MR Sprick, K Kemper, ...
Proceedings of the National Academy of Sciences 105 (36), 13427-13432, 2008
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions
F De Sousa E Melo, X Wang, M Jansen, E Fessler, A Trinh, ...
Nature medicine 19 (5), 614-618, 2013
Intestinal label-retaining cells are secretory precursors expressing Lgr5
SJA Buczacki, HI Zecchini, AM Nicholson, R Russell, L Vermeulen, ...
Nature 495 (7439), 65-69, 2013
Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer
R Dienstmann, L Vermeulen, J Guinney, S Kopetz, S Tejpar, J Tabernero
Nature reviews cancer 17 (2), 79-92, 2017
Cancer Stem Cell Niche: The Place to BeThe Cancer Stem Cell Niche
T Borovski, F De Sousa E Melo, L Vermeulen, JP Medema
Cancer research 71 (3), 634-639, 2011
Microenvironmental regulation of stem cells in intestinal homeostasis and cancer
JP Medema, L Vermeulen
Nature 474 (7351), 318-326, 2011
The developing cancer stem-cell model: clinical challenges and opportunities
L Vermeulen, FS e Melo, DJ Richel, JP Medema
The lancet oncology 13 (2), e83-e89, 2012
Cancer stem cells–old concepts, new insights
L Vermeulen, MR Sprick, K Kemper, G Stassi, JP Medema
Cell Death & Differentiation 15 (6), 947-958, 2008
The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation
K Kemper, MR Sprick, M de Bree, A Scopelliti, L Vermeulen, M Hoek, ...
Cancer research 70 (2), 719-729, 2010
From tumour heterogeneity to advances in precision treatment of colorectal cancer
CJA Punt, M Koopman, L Vermeulen
Nature reviews Clinical oncology 14 (4), 235-246, 2017
Defining stem cell dynamics in models of intestinal tumor initiation
L Vermeulen, E Morrissey, M Van Der Heijden, AM Nicholson, A Sottoriva, ...
Science 342 (6161), 995-998, 2013
Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients
EM Felipe de Sousa, S Colak, J Buikhuisen, J Koster, K Cameron, ...
Cell stem cell 9 (5), 476-485, 2011
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ...
Carcinogenesis 36 (Suppl_1), S254-S296, 2015
Cancer heterogeneity—a multifaceted view
FDSE Melo, L Vermeulen, E Fessler, JP Medema
EMBO reports 14 (8), 686-695, 2013
Targeting Wnt Signaling in Colon Cancer Stem CellsWnt in Colon Cancer Stem Cells
E de Sousa, L Vermeulen, D Richel, JP Medema
Clinical Cancer Research 17 (4), 647-653, 2011
Stem cell dynamics in homeostasis and cancer of the intestine
L Vermeulen, HJ Snippert
Nature Reviews Cancer 14 (7), 468-480, 2014
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ...
The lancet Gastroenterology & hepatology 1 (3), 207-216, 2016
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