Ancestry-inclusive dog genomics challenges popular breed stereotypes K Morrill, J Hekman, X Li, J McClure, B Logan, L Goodman, M Gao, ... Science 376 (6592), eabk0639, 2022 | 101 | 2022 |
Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers N Tonomura, I Elvers, R Thomas, K Megquier, J Turner-Maier, C Howald, ... PLoS genetics 11 (2), e1004922, 2015 | 85 | 2015 |
Comparative genomics reveals shared mutational landscape in canine hemangiosarcoma and human angiosarcoma K Megquier, J Turner-Maier, R Swofford, JH Kim, AL Sarver, C Wang, ... Molecular Cancer Research 17 (12), 2410-2421, 2019 | 82 | 2019 |
Molecular biology and evolution of cancer: from discovery to action JA Somarelli, H Gardner, VL Cannataro, EF Gunady, AM Boddy, ... Molecular biology and evolution 37 (2), 320-326, 2020 | 65 | 2020 |
Genome-wide association study of golden retrievers identifies germ-line risk factors predisposing to mast cell tumours ML Arendt, M Melin, N Tonomura, M Koltookian, C Courtay-Cahen, ... PLoS genetics 11 (11), e1005647, 2015 | 57 | 2015 |
Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy EL Ivansson, K Megquier, SV Kozyrev, E Murén, IB Körberg, R Swofford, ... Proceedings of the National Academy of Sciences 113 (22), E3091-E3100, 2016 | 48 | 2016 |
BarkBase: epigenomic annotation of canine genomes K Megquier, DP Genereux, J Hekman, R Swofford, J Turner-Maier, ... Genes 10 (6), 433, 2019 | 27 | 2019 |
Improving cancer drug discovery by studying cancer across the tree of life JA Somarelli, AM Boddy, HL Gardner, SB DeWitt, J Tuohy, K Megquier, ... Molecular Biology and Evolution 37 (1), 11-17, 2020 | 22 | 2020 |
Genomically complex human angiosarcoma and canine hemangiosarcoma establish convergent angiogenic transcriptional programs driven by novel gene fusions JH Kim, K Megquier, R Thomas, AL Sarver, JM Song, YT Kim, N Cheng, ... Molecular Cancer Research 19 (5), 847-861, 2021 | 18 | 2021 |
Genome-Wide Analyses for Osteosarcoma in Leonberger Dogs Reveal the CDKN2A/B Gene Locus as a Major Risk Locus A Letko, KM Minor, EM Norton, VD Marinescu, M Drögemüller, E Ivansson, ... Genes 12 (12), 1964, 2021 | 13 | 2021 |
Lifetime prevalence of malignant and benign tumours in companion dogs: Cross‐sectional analysis of Dog Aging Project baseline survey SM Schwartz, SR Urfer, M White, K Megquier, S Shrager, ... Veterinary and comparative oncology 20 (4), 797-804, 2022 | 9 | 2022 |
Ancestry-inclusive dog genomics challenges popular breed stereotypes. Science 376, eabk0639 K Morrill, J Hekman, X Li, J McClure, B Logan, L Goodman, M Gao, ... | 9 | 2022 |
Shared hotspot mutations in oncogenes position dogs as an unparalleled comparative model for precision therapeutics L Rodrigues, J Watson, Y Feng, B Lewis, G Harvey, G Post, K Megquier, ... Scientific Reports 13 (1), 10935, 2023 | 6 | 2023 |
The genomic landscape of canine osteosarcoma cell lines reveals conserved structural complexity and pathway alterations K Megquier, J Turner-Maier, K Morrill, X Li, J Johnson, EK Karlsson, ... Plos one 17 (9), e0274383, 2022 | 5 | 2022 |
Shared hotspot mutations in spontaneously arising cancers position dog as an unparalleled comparative model for precision therapeutics L Rodrigues, J Watson, Y Feng, B Lewis, G Harvey, G Post, K Megquier, ... bioRxiv, 2021.10. 22.465469, 2021 | 4 | 2021 |
Identification of genomic alterations with clinical impact in canine splenic hemangiosarcoma T Estabrooks, A Gurinovich, J Pietruska, B Lewis, G Harvey, G Post, ... Veterinary and Comparative Oncology 21 (4), 623-633, 2023 | 2 | 2023 |
Molecular mechanisms that activate convergent oncogenic pathway in genomically complex angiosarcoma JH Kim, K Megquier, AL Sarver, R Thomas, AJ Schulte, C Wang, I Elvers, ... Cancer Research 80 (16_Supplement), 195-195, 2020 | | 2020 |
Advancing blood biopsy through the canine comparative model K Megquier, K Xiong, HL Gardner, J Rhoades, V Adalsteinsson, ... CLINICAL CANCER RESEARCH 26 (11), 64-65, 2020 | | 2020 |
Abstract A58: Advancing blood biopsy through the canine comparative model K Megquier, K Xiong, HL Gardner, J Rhoades, V Adalsteinsson, ... Clinical Cancer Research 26 (11_Supplement), A58-A58, 2020 | | 2020 |
Improving Cancer Drug Discovery by Studying Cancer across the Tree of Life. H Gardner, S DeWitt, J Tuohy, K Megquier, M Sheth, S Hsu, J Thorne, ... Molecular Biology and Evolution 37 (1), 2020 | | 2020 |