SHIP1 inhibition increases immunoregulatory capacity and triggers apoptosis of hematopoietic cancer cells R Brooks, GM Fuhler, S Iyer, MJ Smith, MY Park, KHT Paraiso, ... The Journal of Immunology 184 (7), 3582-3589, 2010 | 150 | 2010 |
Therapeutic potential of SH2 domain-containing inositol-5′-phosphatase 1 (SHIP1) and SHIP2 inhibition in cancer GM Fuhler, R Brooks, B Toms, S Iyer, EA Gengo, MY Park, M Gumbleton, ... Molecular medicine 18, 65-75, 2012 | 128 | 2012 |
Study of the early events leading to cassava root postharvest deterioration S Iyer, DS Mattinson, JK Fellman Tropical plant biology 3, 151-165, 2010 | 115 | 2010 |
Genetically defined syngeneic mouse models of ovarian cancer as tools for the discovery of combination immunotherapy S Iyer, S Zhang, S Yucel, H Horn, SG Smith, F Reinhardt, E Hoefsmit, ... Cancer Discovery 11 (2), 384-407, 2021 | 78 | 2021 |
Extraction of RNA from fresh, frozen, and lyophilized tuber and root tissues GNM Kumar, S Iyer, NR Knowles Journal of agricultural and food chemistry 55 (5), 1674-1678, 2007 | 67 | 2007 |
Genetically defined, syngeneic organoid platform for developing combination therapies for ovarian cancer S Zhang, S Iyer, H Ran, I Dolgalev, S Gu, W Wei, CJR Foster, CA Loomis, ... Cancer discovery 11 (2), 362-383, 2021 | 57 | 2021 |
Strboh A homologue of NADPH oxidase regulates wound-induced oxidative burst and facilitates wound-healing in potato tubers GNM Kumar, S Iyer, NR Knowles Planta 227, 25-36, 2007 | 54 | 2007 |
Role of SHIP1 in cancer and mucosal inflammation S Fernandes, S Iyer, WG Kerr Annals of the New York Academy of Sciences 1280 (1), 6-10, 2013 | 47 | 2013 |
Coordinate expansion of murine hematopoietic and mesenchymal stem cell compartments by SHIPi R Brooks, S Iyer, H Akada, S Neelam, CM Russo, JD Chisholm, WG Kerr Stem Cells 33 (3), 848-858, 2015 | 32 | 2015 |
Role of SHIP1 in bone biology S Iyer, BS Margulies, WG Kerr Annals of the New York Academy of Sciences 1280 (1), 11-14, 2013 | 31 | 2013 |
SHIP1 regulates MSC numbers and their osteolineage commitment by limiting induction of the PI3K/Akt/β-catenin/Id2 axis S Iyer, DR Viernes, JD Chisholm, BS Margulies, WG Kerr Stem cells and development 23 (19), 2336-2351, 2014 | 30 | 2014 |
A small-molecule inhibitor of SHIP1 reverses age-and diet-associated obesity and metabolic syndrome N Srivastava, S Iyer, R Sudan, C Youngs, RW Engelman, KT Howard, ... JCI insight 1 (11), 2016 | 29 | 2016 |
SHIP1-expressing mesenchymal stem cells regulate hematopoietic stem cell homeostasis and lineage commitment during aging S Iyer, R Brooks, M Gumbleton, WG Kerr Stem cells and development 24 (9), 1073-1081, 2015 | 19 | 2015 |
Layer‐by‐layer interleukin‐12 nanoparticles drive a safe and effective response in ovarian tumors AE Barberio, SG Smith, IS Pires, S Iyer, F Reinhardt, MB Melo, H Suh, ... Bioengineering & Translational Medicine 8 (2), e10453, 2023 | 9 | 2023 |
Inaugurating High‐Throughput Profiling of Extracellular Vesicles for Earlier Ovarian Cancer Detection A Jo, A Green, JE Medina, S Iyer, AW Ohman, ET McCarthy, F Reinhardt, ... Advanced Science 10 (27), 2301930, 2023 | 7 | 2023 |
OA15. 05 Hudson: an open-label, multi-drug, biomarker-directed phase 2 study in NSCLC patients who progressed on anti-PD-(L) 1 therapy B Besse, MM Awad, PM Forde, M Thomas, G Goss, B Aronson, R Hobson, ... Journal of Thoracic Oncology 17 (9), S41-S42, 2022 | 7 | 2022 |
ABBV-085 is a novel antibody–drug conjugate (ADC) that targets LRRC15 in the tumor microenvironment J Purcell, J Hickson, S Tanlimco, M Fox, D Chao, E Hsi, M Sho, R Powers, ... European Journal of Cancer 1 (69), S10, 2016 | 7 | 2016 |
Genetically defined, syngeneic organoid platform for developing combination therapies for ovarian cancer. Cancer Discov. 11, 362–383. doi: 10.1158/2159-8290 S Zhang, S Iyer, H Ran, I Dolgalev, S Gu, W Wei, CJR Foster, CA Loomis, ... CD-20-0455, 2020 | 5 | 2020 |
Ship inhibition to combat obesity WG Kerr, I Sonia US Patent App. 14/900,719, 2016 | 4 | 2016 |
Algorithms for expansion and inversion of Davis'z-domain continued fractions R Parthasarathy, S Iyer IEEE transactions on circuits and systems 34 (8), 945-948, 1987 | 4 | 1987 |