Prati
Rajat Varma
Rajat Varma
AstraZeneca
Nema potvrđene e-adrese
Naslov
Citirano
Citirano
Godina
GPI-anchored proteins are organized in submicron domains at the cell surface
R Varma, S Mayor
Nature 394 (6695), 798-801, 1998
14941998
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
R Varma, G Campi, T Yokosuka, T Saito, ML Dustin
Immunity 25 (1), 117-127, 2006
9772006
Nanoscale organization of multiple GPI-anchored proteins in living cell membranes
P Sharma, R Varma, RC Sarasij, K Gousset, G Krishnamoorthy, M Rao, ...
Cell 116 (4), 577-589, 2004
8932004
Actin and agonist MHC–peptide complex–dependent T cell receptor microclusters as scaffolds for signaling
G Campi, R Varma, ML Dustin
The Journal of experimental medicine 202 (8), 1031-1036, 2005
7552005
The immunological synapse balances T cell receptor signaling and degradation
KH Lee, AR Dinner, C Tu, G Campi, S Raychaudhuri, R Varma, TN Sims, ...
science 302 (5648), 1218-1222, 2003
6632003
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins
V Heissmeyer, F Macián, SH Im, R Varma, S Feske, K Venuprasad, H Gu, ...
Nature immunology 5 (3), 255-265, 2004
6112004
Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells
Y Kaizuka, AD Douglass, R Varma, ML Dustin, RD Vale
Proceedings of the National Academy of Sciences 104 (51), 20296-20301, 2007
4252007
Opposing effects of PKCθ and WASp on symmetry breaking and relocation of the immunological synapse
TN Sims, TJ Soos, HS Xenias, B Dubin-Thaler, JM Hofman, JC Waite, ...
Cell 129 (4), 773-785, 2007
4042007
Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes
D Skokos, G Shakhar, R Varma, JC Waite, TO Cameron, RL Lindquist, ...
Nature immunology 8 (8), 835-844, 2007
2352007
Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster
S Vardhana, K Choudhuri, R Varma, ML Dustin
Immunity 32 (4), 531-540, 2010
1882010
Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance
DC Palmer, GC Guittard, Z Franco, JG Crompton, RL Eil, SJ Patel, Y Ji, ...
Journal of Experimental Medicine 212 (12), 2095-2113, 2015
1872015
Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain
AM Beal, N Anikeeva, R Varma, TO Cameron, G Vasiliver-Shamis, ...
Immunity 31 (4), 632-642, 2009
1382009
T cell–dendritic cell immunological synapses
ML Dustin, SY Tseng, R Varma, G Campi
Current opinion in immunology 18 (4), 512-516, 2006
1202006
Supported planar bilayers for study of the immunological synapse
ML Dustin, T Starr, R Varma, VK Thomas
Current protocols in immunology 76 (1), 18.13. 1-18.13. 35, 2007
1032007
The Class II Phosphatidylinositol 3 kinase C2β Is Required for the Activation of the K+ Channel KCa3.1 and CD4 T-Cells
S Srivastava, L Di, O Zhdanova, Z Li, S Vardhana, Q Wan, Y Yan, ...
Molecular biology of the cell 20 (17), 3783-3791, 2009
902009
Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters
X Lu, JS Gibbs, HD Hickman, A David, BP Dolan, Y Jin, DM Kranz, ...
Proceedings of the National Academy of Sciences 109 (38), 15407-15412, 2012
822012
Protein kinase Cθ regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL
AM Beal, N Anikeeva, R Varma, TO Cameron, PJ Norris, ML Dustin, ...
The Journal of Immunology 181 (7), 4815-4824, 2008
762008
Dissection of specific binding of HIV-1 Gag to the'packaging signal'in viral RNA
M Comas-Garcia, SAK Datta, L Baker, R Varma, PR Gudla, A Rein
Elife 6, e27055, 2017
672017
Fluorescence methods to probe nanometer-scale organization of molecules in living cell membranes
RV Krishnan, R Varma, S Mayor
Journal of fluorescence 11, 211-226, 2001
612001
TCR Microclusters pre-exist and contain molecules necessary for TCR signal transduction
TJ Crites, K Padhan, J Muller, M Krogsgaard, PR Gudla, SJ Lockett, ...
The Journal of Immunology 193 (1), 56-67, 2014
582014
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