Ravi Iyengar
Ravi Iyengar
Professor , Pharmacology , Icahn School of Medicine at Mount Sinai Mount Sinai School of Medicine
Potvrđena adresa e-pošte na
Emergent properties of networks of biological signaling pathways
US Bhalla, R Iyengar
Science 283 (5400), 381-387, 1999
G protein pathways
SR Neves, PT Ram, R Iyengar
Science 296 (5573), 1636-1639, 2002
Functional atlas of the integrin adhesome
R Zaidel-Bar, S Itzkovitz, A Ma'ayan, R Iyengar, B Geiger
Nature cell biology 9 (8), 858-867, 2007
Complexity in biological signaling systems
G Weng, US Bhalla, R Iyengar
Science 284 (5411), 92-96, 1999
MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network
US Bhalla, PT Ram, R Iyengar
Science 297 (5583), 1018-1023, 2002
Molecular basis for interactions of G protein βγ subunits with effectors
CE Ford, NP Skiba, H Bae, Y Daaka, E Reuveny, LR Shekter, R Rosal, ...
Science 280 (5367), 1271-1274, 1998
Signaling networks: the origins of cellular multitasking
JD Jordan, EM Landau, R Iyengar
Cell 103 (2), 193-200, 2000
Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP
RD Blitzer, JH Connor, GP Brown, T Wong, S Shenolikar, R Iyengar, ...
Science 280 (5371), 1940-1943, 1998
Network analyses in systems pharmacology
SI Berger, R Iyengar
Bioinformatics 25 (19), 2466-2472, 2009
Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair
V Cordeddu, E Di Schiavi, LA Pennacchio, A Ma'ayan, A Sarkozy, ...
Nature genetics 41 (9), 1022-1026, 2009
Molecular and functional diversity of mammalian Gs‐stimulated adenylyl cyclases
R Iyengar
The FASEB Journal 7 (9), 768-775, 1993
The G protein-gated atrial K+ channel is stimulated by three distinct Giα-subunits
A Yatani, R Mattera, J Codina, R Graf, K Okabe, E Padrell, R Iyengar, ...
Nature 336 (6200), 680-682, 1988
Stimulation and inhibition of adenylyl cyclases mediated by distinct regulatory proteins
JD Hildebrandt, RD Sekura, J Codina, R Iyengar, CR Manclark, ...
Nature 302 (5910), 706-709, 1983
Formation of regulatory patterns during signal propagation in a mammalian cellular network
A Ma'ayan, SL Jenkins, S Neves, A Hasseldine, E Grace, B Dubin-Thaler, ...
Science 309 (5737), 1078-1083, 2005
Postsynaptic cAMP pathway gates early LTP in hippocampal CA1 region
RD Blitzer, T Wong, R Nouranifar, R Iyengar, EM Landau
Neuron 15 (6), 1403-1414, 1995
Systems approaches to polypharmacology and drug discovery
ADW Boran, R Iyengar
Current opinion in drug discovery & development 13 (3), 297, 2010
Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesium.
J Codina, J Hildebrandt, R Iyengar, L Birnbaumer, RD Sekura, ...
Proceedings of the National Academy of Sciences 80 (14), 4276-4280, 1983
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
S Zhao, R Iyengar
Annual review of pharmacology and toxicology 52, 505, 2012
A region of adenylyl cyclase 2 critical for regulation by G protein βγ subunits
J Chen, M DeVivo, J Dingus, A Harry, J Li, J Sui, DJ Carty, JL Blank, ...
Science 268 (5214), 1166-1169, 1995
Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks
SR Neves, P Tsokas, A Sarkar, EA Grace, P Rangamani, SM Taubenfeld, ...
Cell 133 (4), 666-680, 2008
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