Prati
Greg Sienski
Greg Sienski
Discovery Sciences, AstraZeneca
Potvrđena adresa e-pošte na astrazeneca.com
Naslov
Citirano
Citirano
Godina
Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression
G Sienski, D Dönertas, J Brennecke
Cell 151 (5), 964-980, 2012
6462012
The Rhino-Deadlock-Cutoff Complex Licenses Noncanonical Transcription of Dual-Strand piRNA Clusters in Drosophila
F Mohn, G Sienski, D Handler, J Brennecke
Cell 157 (6), 1364-1379, 2014
3762014
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia
G Sienski, P Narayan, JM Bonner, N Kory, S Boland, AA Arczewska, ...
Science translational medicine 13 (583), eaaz4564, 2021
1962021
Silencio/CG9754 connects the Piwi–piRNA complex to the cellular heterochromatin machinery
G Sienski, J Batki, KA Senti, D Dönertas, L Tirian, K Meixner, J Brennecke
Genes & development 29 (21), 2258-2271, 2015
1682015
Drosophila Gtsf1 is an essential component of the Piwi-mediated transcriptional silencing complex
D Dönertas, G Sienski, J Brennecke
Genes & development 27 (15), 1693-1705, 2013
1542013
Efficient CRISPR/Cas9 plasmids for rapid and versatile genome editing in Drosophila
J Gokcezade, G Sienski, P Duchek
G3: Genes, Genomes, Genetics 4 (11), 2279-2282, 2014
1252014
Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway
GI Karras, M Fumasoni, G Sienski, F Vanoli, D Branzei, S Jentsch
Molecular cell 49 (3), 536-546, 2013
1102013
PICALM rescues endocytic defects caused by the Alzheimer’s disease risk factor APOE4
P Narayan, G Sienski, JM Bonner, YT Lin, J Seo, V Baru, A Haque, B Milo, ...
Cell reports 33 (1), 2020
562020
Universal toxin-based selection for precise genome engineering in human cells
S Li, N Akrap, S Cerboni, MJ Porritt, S Wimberger, A Lundin, C Möller, ...
Nature communications 12 (1), 497, 2021
282021
Harnessing DSB repair to promote efficient homology-dependent and-independent prime editing
M Peterka, N Akrap, S Li, S Wimberger, PP Hsieh, D Degtev, B Bestas, ...
Nature Communications 13 (1), 1240, 2022
232022
Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery
VI Andreev, C Yu, J Wang, J Schnabl, L Tirian, M Gehre, D Handler, ...
Nature Structural & Molecular Biology 29 (2), 130-142, 2022
202022
The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma
R Schwentner, D Herrero-Martin, MO Kauer, CN Mutz, AM Katschnig, ...
Oncotarget 8 (7), 10980, 2017
182017
TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis
K Petkevicius, H Palmgren, MS Glover, A Ahnmark, AC Andréasson, ...
Nature Communications 13 (1), 6020, 2022
62022
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo
B Bestas, S Wimberger, D Degtev, A Madsen, AK Rottner, F Karlsson, ...
Nature Communications 14 (1), 5474, 2023
32023
The use of choline supplementation as therapy for apoe4-related disorders
LH Tsai, YT Lin, J Bonner, P Narayan, G Sienski
US Patent App. 17/318,921, 2021
2021
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