The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. CM Gorman, GT Merlino, MC Willingham, I Pastan, BH Howard Proceedings of the National Academy of Sciences 79 (22), 6777-6781, 1982 | 1635 | 1982 |
TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas C Jhappan, C Stahle, RN Harkins, N Fausto, GH Smith, GT Merlino Cell 61 (6), 1137-1146, 1990 | 833 | 1990 |
Identification of essential genes for cancer immunotherapy SJ Patel, NE Sanjana, RJ Kishton, A Eidizadeh, SK Vodnala, M Cam, ... Nature 548 (7669), 537-542, 2017 | 803 | 2017 |
Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators Y Yu, J Khan, C Khanna, L Helman, PS Meltzer, G Merlino Nature medicine 10 (2), 175-181, 2004 | 744 | 2004 |
The two faces of interferon-γ in cancer MR Zaidi, G Merlino Clinical cancer research 17 (19), 6118-6124, 2011 | 741 | 2011 |
Preclinical mouse cancer models: a maze of opportunities and challenges CP Day, G Merlino, T Van Dyke Cell 163 (1), 39-53, 2015 | 654 | 2015 |
Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry X Feng, MS Degese, R Iglesias-Bartolome, JP Vaque, AA Molinolo, ... Cancer cell 25 (6), 831-845, 2014 | 576 | 2014 |
Epidermal-growth-factor-dependent transformation by a human EGF receptor proto-oncogene TJ Velu, L Beguinot, WC Vass, MC Willingham, GT Merlino, I Pastan, ... Science 238 (4832), 1408-1410, 1987 | 569 | 1987 |
Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor H Takayama, WJ LaRochelle, R Sharp, T Otsuka, P Kriebel, M Anver, ... Proceedings of the National Academy of Sciences 94 (2), 701-706, 1997 | 564 | 1997 |
Lifetime exposure to a soluble TGF-β antagonist protects mice against metastasis without adverse side effects Y Yang, O Dukhanina, B Tang, M Mamura, JJ Letterio, J MacGregor, ... The Journal of clinical investigation 109 (12), 1607-1615, 2002 | 494 | 2002 |
Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands. C Jhappan, D Gallahan, C Stahle, E Chu, GH Smith, G Merlino, ... Genes & development 6 (3), 345-355, 1992 | 484 | 1992 |
Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene. S Ishii, YHUA Xu, RH Stratton, BA Roe, GT Merlino, I Pastan Proceedings of the National Academy of Sciences 82 (15), 4920-4924, 1985 | 465 | 1985 |
Amplification and enhanced expression of the epidermal growth factor receptor gene in A431 human carcinoma cells GT Merlino, YH Xu, S Ishii, AJL Clark, K Semba, K Toyoshima, ... Science 224 (4647), 417-419, 1984 | 462 | 1984 |
Neonatal sunburn and melanoma in mice FP Noonan, JA Recio, H Takayama, P Duray, MR Anver, WL Rush, ... Nature 413 (6853), 271-272, 2001 | 455 | 2001 |
Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning G Celli, WJ LaRochelle, S Mackem, R Sharp, G Merlino The EMBO journal 17 (6), 1642-1655, 1998 | 452 | 1998 |
Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response CN Spencer, JL McQuade, V Gopalakrishnan, JA McCulloch, M Vetizou, ... Science 374 (6575), 1632-1640, 2021 | 424 | 2021 |
Ultraviolet radiation and cutaneous malignant melanoma C Jhappan, FP Noonan, G Merlino Oncogene 22 (20), 3099-3112, 2003 | 381 | 2003 |
Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models JGT Vi, AT Cheuk, PS Tsang, JY Chung, YK Song, K Desai, Y Yu, ... The Journal of clinical investigation 119 (11), 3395-3407, 2009 | 360 | 2009 |
Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment FP Noonan, MR Zaidi, A Wolnicka-Glubisz, MR Anver, J Bahn, A Wielgus, ... Nature communications 3 (1), 884, 2012 | 357 | 2012 |
Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha. JC Wu, G Merlino, N Fausto Proceedings of the National Academy of Sciences 91 (2), 674-678, 1994 | 353 | 1994 |