Unfolding and aggregation of monoclonal antibodies on cation exchange columns: effects of resin type, load buffer, and protein stability J Guo, G Carta Journal of Chromatography A 1388, 184-194, 2015 | 61 | 2015 |
Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part I. Chromatographic elution and batch adsorption behavior J Guo, S Zhang, G Carta Journal of Chromatography A 1356, 117-128, 2014 | 61 | 2014 |
Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part II. Protein structure effects by hydrogen deuterium exchange mass spectrometry J Guo, G Carta Journal of Chromatography A 1356, 129-137, 2014 | 48 | 2014 |
Surface induced three-peak elution behavior of a monoclonal antibody during cation exchange chromatography J Guo, AD Creasy, G Barker, G Carta Journal of Chromatography A 1474, 85-94, 2016 | 28 | 2016 |
Optimization of Single‐Column Batch and Multicolumn Continuous Protein A Chromatography and Performance Comparison Based on Mechanistic Model J Guo, M Jin, D Kanani Biotechnology Journal 15 (10), 2000192, 2020 | 19 | 2020 |
Host Cell Proteins During Biomanufacturing JY Baik, J Guo, KH Lee Cell Culture Engineering: Recombinant Protein Production, 295-311, 2019 | 8 | 2019 |
Mechanisms of precipitate formation during the purification of an Fc‐fusion protein DG Greene, SJ Traylor, J Guo, LH Choe, S Modla, X Xu, N Singh, LL Lock, ... Biotechnology and bioengineering 115 (10), 2489-2503, 2018 | 8 | 2018 |
Effect of solution condition on the binding behaviors of monoclonal antibody and fusion protein therapeutics in Protein A chromatography J Guo, S Noyes, W Jin, H Curtis, X Xu, S Ghose Journal of Chromatography A 1686, 463652, 2022 | 5 | 2022 |
Engineering protein A ligands to mitigate antibody loss during high-pH washes in protein A chromatography S Bhoyar, M Foster, YH Oh, X Xu, SJ Traylor, J Guo, S Ghose, AM Lenhoff Journal of Chromatography A 1696, 463962, 2023 | 3 | 2023 |
Predictive mechanistic modeling of loading and elution in protein A chromatography S Bhoyar, V Kumar, M Foster, X Xu, SJ Traylor, J Guo, AM Lenhoff Journal of Chromatography A 1713, 464558, 2024 | 2 | 2024 |
Conformational changes of biomolecules in ion-exchange chromatography J Guo, X Xu Ion-Exchange Chromatography and Related Techniques, 521-534, 2024 | 1 | 2024 |
Model-Based Analysis of the Monoclonal Antibody Glycosylation across CHO Cell Lines J Guo, Y Ma, R Braatz 2024 AIChE Annual Meeting, 2024 | | 2024 |
Nonlinear Model Predictive Control of the Monoclonal Antibody Glycosylation in Cell Culture Y Ma, J Guo, R Braatz 2024 AIChE Annual Meeting, 2024 | | 2024 |
Hydrophobic Interaction Chromatography in Continuous Flow-Through Mode for Product-Related Variant Removal Y Wang, U Bhaskar, N Chennamsetty, S Noyes, J Guo, Y Song, ... Journal of Chromatography A, 465356, 2024 | | 2024 |
Quasi-Steady-State Approach for Efficient Multiscale Simulation and Optimization of mAb Glycosylation in CHO Culture Y Ma, J Guo, R Braatz arXiv preprint arXiv:2409.00281, 2024 | | 2024 |
Modeling scalability of impurity precipitation in downstream biomanufacturing J Guo, SJ Traylor, M Agoub, W Jin, H Hua, RB Diemer, X Xu, S Ghose, ... Biotechnology Progress, e3454, 2024 | | 2024 |
Glycopy: A Multiscale Model-Based Simulation, Optimization, and Optimal Control Python Package for Monoclonal Antibody Glycosylation in Cell Culture Y Ma, J Guo, R Braatz 2023 AIChE Annual Meeting, 2023 | | 2023 |
Model-Based Design of Experiments for Antibody Glycosylation in CHO Cell Culture J Guo, Y Ma, RD Braatz 2023 AIChE Annual Meeting, 2023 | | 2023 |
Manufacturing scalability of isoelectric impurity precipitation during viral inactivation neutralization S Traylor, W Jin, H Hua, J Guo, J Lee, X Xu, A Lenhoff, S Ghose ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
Optimization of batch and continuous multi-column protein A chromatography with mechanistic model and experiments J Guo, S Zhang, D Kanani, M Jin ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |