| Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes NG Ravindra, MM Alfajaro, V Gasque, NC Huston, H Wan, K Szigeti-Buck, ... PLoS biology 19 (3), e3001143, 2021 | 261* | 2021 |
| Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms NC Huston, H Wan, MS Strine, RCA Tavares, CB Wilen, AM Pyle Molecular cell 81 (3), 584-598. e5, 2021 | 228 | 2021 |
| Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals AS Grillo, AM SantaMaria, MD Kafina, AG Cioffi, NC Huston, M Han, ... Science 356 (6338), 608-616, 2017 | 138 | 2017 |
| Mitochondrial ClpX activates a key enzyme for heme biosynthesis and erythropoiesis JR Kardon, YY Yien, NC Huston, DS Branco, GJ Hildick-Smith, KY Rhee, ... Cell 161 (4), 858-867, 2015 | 112 | 2015 |
| The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability J Chung, DE Bauer, A Ghamari, CP Nizzi, KM Deck, PD Kingsley, YY Yien, ... Science signaling 8 (372), ra34-ra34, 2015 | 73 | 2015 |
| Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4 GJ Hildick-Smith, JD Cooney, C Garone, LS Kremer, TB Haack, JN Thon, ... The American Journal of Human Genetics 93 (5), 906-914, 2013 | 68 | 2013 |
| The global and local distribution of RNA structure throughout the SARS-CoV-2 genome RCA Tavares, G Mahadeshwar, H Wan, NC Huston, AM Pyle Journal of Virology 95 (5), 10.1128/jvi. 02190-20, 2021 | 55 | 2021 |
| Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria J Chung, SA Anderson, B Gwynn, KM Deck, MJ Chen, NB Langer, ... Journal of Biological Chemistry 289 (11), 7835-7843, 2014 | 50 | 2014 |
| Sequencing and structure probing of long RNAs using MarathonRT: a next-generation reverse transcriptase LT Guo, RL Adams, H Wan, NC Huston, O Potapova, S Olson, ... Journal of molecular biology 432 (10), 3338-3352, 2020 | 45 | 2020 |
| Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes A Seguin, N Takahashi-Makise, YY Yien, NC Huston, JC Whitman, ... Journal of Biological Chemistry 292 (39), 16284-16299, 2017 | 39 | 2017 |
| Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells J Tycko, LA Barrera, NC Huston, AE Friedland, X Wu, JS Gootenberg, ... Nature communications 9 (1), 2962, 2018 | 34 | 2018 |
| Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression H Anderson, TC Patch, PNG Reddy, EJ Hagedorn, PG Kim, KA Soltis, ... Blood, The Journal of the American Society of Hematology 126 (26), 2811-2820, 2015 | 29 | 2015 |
| Identification of guide-intrinsic determinants of Cas9 specificity NC Huston, J Tycko, EL Tillotson, CJ Wilson, VE Myer, H Jayaram, ... The CRISPR journal 2 (3), 172-185, 2019 | 22 | 2019 |
| Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia BE Shmukler, NC Huston, JN Thon, CW Ni, G Kourkoulis, ND Lawson, ... Haematologica 100 (12), e483, 2015 | 22 | 2015 |
| Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo AL Schober, DA Gagarkin, Y Chen, G Gao, L Jacobson, AA Mongin Frontiers in cellular neuroscience 10, 262, 2016 | 21 | 2016 |
| Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital sideroblastic anemia A Crispin, C Guo, C Chen, DR Campagna, PJ Schmidt, D Lichtenstein, ... The Journal of clinical investigation 130 (10), 5245-5256, 2020 | 20 | 2020 |
| Crispr/Cas-Related Methods and Compositions for Treating Duchenne Muscular Dystrophy and Becker PD Hsu, ML Maeder, P Odonnell, JC Tycko, NC Huston US Patent App. 15/732,190, 2019 | 8 | 2019 |
| Sensitive detection of structural features and rearrangements in long, structured RNA molecules RL Adams, NC Huston, RCA Tavares, AM Pyle Methods in Enzymology 623, 249-289, 2019 | 8 | 2019 |
| CRISPR/CAS RELATED METHODS AND COMPOSITIONS FOR TREATING DUCHENNE MUSCLE DYSTROPHY DA Bumcrot, NC Huston, JC Tycko, J Robinson-Hamm, CA Gersbach | 7 | 2019 |
| Fam210b is required for optimal cellular and mitochondrial iron uptake during erythroid differentiation YY Yien, C Chen, J Shi, L Li, DE Bauer, N Huston, PD Kingsley, J Ablain, ... Blood 126 (23), 405, 2015 | 3 | 2015 |
