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Andrew D. Southam
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High-throughput tissue extraction protocol for NMR-and MS-based metabolomics
H Wu, AD Southam, A Hines, MR Viant
Analytical biochemistry 372 (2), 204-212, 2008
6812008
Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the …
AD Southam, TG Payne, HJ Cooper, TN Arvanitis, MR Viant
Analytical chemistry 79 (12), 4595-4602, 2007
2332007
Birmingham Metabolite Library: a publicly accessible database of 1-D 1H and 2-D 1H J-resolved NMR spectra of authentic metabolite standards (BML-NMR)
C Ludwig, JM Easton, A Lodi, S Tiziani, SE Manzoor, AD Southam, ...
Metabolomics 8, 8-18, 2012
1612012
A complete workflow for high-resolution spectral-stitching nanoelectrospray direct-infusion mass-spectrometry-based metabolomics and lipidomics
AD Southam, RJM Weber, J Engel, MR Jones, MR Viant
Nature protocols 12 (2), 310-328, 2017
1522017
A new approach to toxicity testing in Daphnia magna: application of high throughput FT-ICR mass spectrometry metabolomics
NS Taylor, RJM Weber, AD Southam, TG Payne, O Hrydziuszko, ...
Metabolomics 5, 44-58, 2009
1482009
Characterization of isotopic abundance measurements in high resolution FT-ICR and Orbitrap mass spectra for improved confidence of metabolite identification
RJM Weber, AD Southam, U Sommer, MR Viant
Analytical chemistry 83 (10), 3737-3743, 2011
1352011
Monitoring cancer prognosis, diagnosis and treatment efficacy using metabolomics and lipidomics
EG Armitage, AD Southam
Metabolomics 12, 1-15, 2016
1272016
Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity
L Fultang, S Booth, O Yogev, B Martins da Costa, V Tubb, S Panetti, ...
Blood, The Journal of the American Society of Hematology 136 (10), 1155-1160, 2020
1032020
Metabolomics reveals target and off-target toxicities of a model organophosphate pesticide to roach (Rutilus rutilus): implications for biomonitoring
AD Southam, A Lange, A Hines, EM Hill, Y Katsu, T Iguchi, CR Tyler, ...
Environmental science & technology 45 (8), 3759-3767, 2011
912011
A signal filtering method for improved quantification and noise discrimination in fourier transform ion cyclotron resonance mass spectrometry-based metabolomics data
TG Payne, AD Southam, TN Arvanitis, MR Viant
Journal of the American Society for Mass Spectrometry 20, 1087-1095, 2009
862009
International ring trial of a high resolution targeted metabolomics and lipidomics platform for serum and plasma analysis
JW Thompson, KJ Adams, J Adamski, Y Asad, D Borts, JA Bowden, ...
Analytical chemistry 91 (22), 14407-14416, 2019
792019
Metabolic changes in flatfish hepatic tumours revealed by NMR-based metabolomics and metabolic correlation networks
AD Southam, JM Easton, GD Stentiford, C Ludwig, TN Arvanitis, MR Viant
Journal of proteome research 7 (12), 5277-5285, 2008
702008
Drug redeployment to kill leukemia and lymphoma cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids
AD Southam, FL Khanim, RE Hayden, JK Constantinou, KM Koczula, ...
Cancer research 75 (12), 2530-2540, 2015
652015
Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques
JL Denbigh, D Perez-Guaita, RR Vernooij, MJ Tobin, KR Bambery, Y Xu, ...
Scientific Reports 7 (1), 2649, 2017
342017
Distinguishing between the metabolome and xenobiotic exposome in environmental field samples analysed by direct-infusion mass spectrometry based metabolomics and lipidomics
AD Southam, A Lange, R Al-Salhi, EM Hill, CR Tyler, MR Viant
Metabolomics 10 (6), 1050-1058, 2014
342014
Assessment of human plasma and urine sample preparation for reproducible and high-throughput UHPLC-MS clinical metabolic phenotyping
AD Southam, LD Haglington, L Najdekr, A Jankevics, RJM Weber, ...
Analyst 145 (20), 6511-6523, 2020
312020
Disruption of DNA Methylation via S-Adenosylhomocysteine Is a Key Process in High Incidence Liver Carcinogenesis in Fish
L Mirbahai, AD Southam, U Sommer, TD Williams, JP Bignell, BP Lyons, ...
Journal of proteome research 12 (6), 2895-2904, 2013
302013
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
DJ Wilcock, AP Badrock, CW Wong, R Owen, M Guerin, AD Southam, ...
Cell reports 39 (12), 2022
222022
Aromatic metabolites from the coelomic fluid of Eisenia earthworm species
S Rochfort, MA Wyatt, M Liebeke, AD Southam, MR Viant, JG Bundy
European journal of soil biology 78, 17-19, 2017
212017
Metabolomics reveal potential natural substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium
X Wang-Kan, G Rodríguez-Blanco, AD Southam, CL Winder, WB Dunn, ...
MBio 12 (2), 10.1128/mbio. 00109-21, 2021
202021
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Articles 1–20