The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 48 (4), 812-830. e14, 2018 | 4807 | 2018 |
An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ... Cell 173 (2), 400-416. e11, 2018 | 2889 | 2018 |
Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 2709 | 2018 |
Comprehensive characterization of cancer driver genes and mutations MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ... Cell 173 (2), 371-385. e18, 2018 | 2316 | 2018 |
Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ... Cell 173 (2), 291-304. e6, 2018 | 2176 | 2018 |
Machine learning identifies stemness features associated with oncogenic dedifferentiation TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ... Cell 173 (2), 338-354. e15, 2018 | 1752 | 2018 |
Malignant mesothelioma BWS Robinson, AW Musk, RA Lake The Lancet 366 (9483), 397-408, 2005 | 991 | 2005 |
Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas TA Knijnenburg, L Wang, MT Zimmermann, N Chambwe, GF Gao, ... Cell reports 23 (1), 239-254. e6, 2018 | 984 | 2018 |
Genomic and functional approaches to understanding cancer aneuploidy AM Taylor, J Shih, G Ha, GF Gao, X Zhang, AC Berger, SE Schumacher, ... Cancer cell 33 (4), 676-689. e3, 2018 | 953 | 2018 |
Spatial organization and molecular correlation of tumor-infiltrating lymphocytes using deep learning on pathology images J Saltz, R Gupta, L Hou, T Kurc, P Singh, V Nguyen, D Samaras, ... Cell reports 23 (1), 181-193. e7, 2018 | 903 | 2018 |
The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ... Cell reports 23 (1), 313-326. e5, 2018 | 892 | 2018 |
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21. 1 losses in malignant pleural mesothelioma M Bott, M Brevet, BS Taylor, S Shimizu, T Ito, L Wang, J Creaney, RA Lake, ... Nature genetics 43 (7), 668-672, 2011 | 804 | 2011 |
Comprehensive analysis of alternative splicing across tumors from 8,705 patients A Kahles, KV Lehmann, NC Toussaint, M Hüser, SG Stark, ... Cancer cell 34 (2), 211-224. e6, 2018 | 792 | 2018 |
Pathogenic germline variants in 10,389 adult cancers K Huang, RJ Mashl, Y Wu, DI Ritter, J Wang, C Oh, M Paczkowska, ... Cell 173 (2), 355-370. e14, 2018 | 767 | 2018 |
Scalable open science approach for mutation calling of tumor exomes using multiple genomic pipelines K Ellrott, MH Bailey, G Saksena, KR Covington, C Kandoth, C Stewart, ... Cell systems 6 (3), 271-281. e7, 2018 | 680 | 2018 |
Mesothelin-family proteins and diagnosis of mesothelioma BWS Robinson, J Creaney, R Lake, A Nowak, AW Musk, N de Klerk, ... The Lancet 362 (9396), 1612-1616, 2003 | 663 | 2003 |
A comprehensive pan-cancer molecular study of gynecologic and breast cancers AC Berger, A Korkut, RS Kanchi, AM Hegde, W Lenoir, W Liu, Y Liu, ... Cancer cell 33 (4), 690-705. e9, 2018 | 598 | 2018 |
Integrative molecular characterization of malignant pleural mesothelioma J Hmeljak, F Sanchez-Vega, KA Hoadley, J Shih, C Stewart, D Heiman, ... Cancer discovery 8 (12), 1548-1565, 2018 | 538 | 2018 |
Driver fusions and their implications in the development and treatment of human cancers Q Gao, WW Liang, SM Foltz, G Mutharasu, RG Jayasinghe, S Cao, ... Cell reports 23 (1), 227-238. e3, 2018 | 526 | 2018 |
Comparative molecular analysis of gastrointestinal adenocarcinomas Y Liu, NS Sethi, T Hinoue, BG Schneider, AD Cherniack, F Sanchez-Vega, ... Cancer cell 33 (4), 721-735. e8, 2018 | 518 | 2018 |