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| Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma CU Louis, B Savoldo, G Dotti, M Pule, E Yvon, GD Myers, C Rossig, ... Blood, The Journal of the American Society of Hematology 118 (23), 6050-6056, 2011 | 1293 | 2011 |
| Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells W Qasim, H Zhan, S Samarasinghe, S Adams, P Amrolia, S Stafford, ... Science translational medicine 9 (374), eaaj2013, 2017 | 949 | 2017 |
| Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients HE Heslop, KS Slobod, MA Pule, GA Hale, A Rousseau, CA Smith, ... Blood, The Journal of the American Society of Hematology 115 (5), 925-935, 2010 | 899 | 2010 |
| An inducible caspase 9 safety switch for T-cell therapy KC Straathof, MA Pule, P Yotnda, G Dotti, EF Vanin, MK Brenner, ... Blood 105 (11), 4247-4254, 2005 | 800 | 2005 |
| Multiplex genome-edited T-cell manufacturing platform for “off-the-shelf” adoptive T-cell immunotherapies L Poirot, B Philip, C Schiffer-Mannioui, D Le Clerre, I Chion-Sotinel, ... Cancer research 75 (18), 3853-3864, 2015 | 623 | 2015 |
| A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells MA Pulè, KC Straathof, G Dotti, HE Heslop, CM Rooney, MK Brenner Molecular Therapy 12 (5), 933-941, 2005 | 574 | 2005 |
| Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b JA Craddock, AN Lu, A Bear, M Pule, MK Brenner, CM Rooney, AE Foster Journal of immunotherapy 33 (8), 780-788, 2010 | 559 | 2010 |
| Fc effector function contributes to the activity of human anti-CTLA-4 antibodies FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ... Cancer cell 33 (4), 649-663. e4, 2018 | 537 | 2018 |
| Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR S Ghorashian, AM Kramer, S Onuoha, G Wright, J Bartram, R Richardson, ... Nature medicine 25 (9), 1408-1414, 2019 | 465 | 2019 |
| Deep in vivo photoacoustic imaging of mammalian tissues using a tyrosinase-based genetic reporter AP Jathoul, J Laufer, O Ogunlade, B Treeby, B Cox, E Zhang, P Johnson, ... Nature Photonics 9 (4), 239-246, 2015 | 465 | 2015 |
| A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy B Philip, E Kokalaki, L Mekkaoui, S Thomas, K Straathof, B Flutter, ... Blood, The Journal of the American Society of Hematology 124 (8), 1277-1287, 2014 | 427 | 2014 |
| Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ... Immunity 46 (4), 577-586, 2017 | 411 | 2017 |
| T lymphocytes redirected against the κ light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells J Vera, B Savoldo, S Vigouroux, E Biagi, M Pule, C Rossig, J Wu, ... Blood 108 (12), 3890-3897, 2006 | 332 | 2006 |
| The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma A Slack, Z Chen, R Tonelli, M Pule, L Hunt, A Pession, JM Shohet Proceedings of the National Academy of Sciences 102 (3), 731-736, 2005 | 281 | 2005 |
| Addition of the CD28 signaling domain to chimeric T-cell receptors enhances chimeric T-cell resistance to T regulatory cells A Loskog, V Giandomenico, C Rossig, M Pule, G Dotti, MK Brenner Leukemia 20 (10), 1819-1828, 2006 | 239 | 2006 |
| CAR–T cells and solid tumors: tuning T cells to challenge an inveterate foe DE Gilham, R Debets, M Pule, RE Hawkins, H Abken Trends in molecular medicine 18 (7), 377-384, 2012 | 236 | 2012 |
| 2B4 (CD244) signaling by recombinant antigen-specific chimeric receptors costimulates natural killer cell activation to leukemia and neuroblastoma cells B Altvater, S Landmeier, S Pscherer, J Temme, K Schweer, S Kailayangiri, ... Clinical Cancer Research 15 (15), 4857-4866, 2009 | 231 | 2009 |
| Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies PM Maciocia, PA Wawrzyniecka, B Philip, I Ricciardelli, AU Akarca, ... Nature medicine 23 (12), 1416-1423, 2017 | 228 | 2017 |
| Red-emitting luciferases for bioluminescence reporter and imaging applications BR Branchini, DM Ablamsky, AL Davis, TL Southworth, B Butler, F Fan, ... Analytical biochemistry 396 (2), 290-297, 2010 | 224 | 2010 |
