Core signaling pathways in human pancreatic cancers revealed by global genomic analyses S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ... science 321 (5897), 1801-1806, 2008 | 4737 | 2008 |
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor … G Dranoff, E Jaffee, A Lazenby, P Golumbek, H Levitsky, K Brose, ... Proceedings of the National Academy of Sciences 90 (8), 3539-3543, 1993 | 3429 | 1993 |
Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens AYC Huang, P Golumbek, M Ahmadzadeh, E Jaffee, D Pardoll, H Levitsky Science 264 (5161), 961-965, 1994 | 1529 | 1994 |
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ... Science 324 (5924), 217-217, 2009 | 1041 | 2009 |
Mechanisms of immune evasion by tumors CG Drake, E Jaffee, DM Pardoll Advances in immunology 90, 51-81, 2006 | 895 | 2006 |
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene … P Argani, C Iacobuzio-Donahue, B Ryu, C Rosty, M Goggins, RE Wilentz, ... Clinical cancer research 7 (12), 3862-3868, 2001 | 723 | 2001 |
Novel allogeneic granulocyte-macrophage colony-stimulating factor–secreting tumor vaccine for pancreatic cancer: a phase I trial of safety and immune activation EM Jaffee, RH Hruban, B Biedrzycki, D Laheru, K Schepers, PR Sauter, ... Journal of Clinical Oncology 19 (1), 145-156, 2001 | 689 | 2001 |
Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes–Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer DT Le, A Wang-Gillam, V Picozzi, TF Greten, T Crocenzi, G Springett, ... Journal of clinical Oncology 33 (12), 1325-1333, 2015 | 670 | 2015 |
Compromised HOXA5 function can limit p53 expression in human breast tumours V Raman, SA Martensen, D Reisman, E Evron, WF Odenwald, E Jaffee, ... Nature 405 (6789), 974-978, 2000 | 638 | 2000 |
Evaluation of ipilimumab in combination with allogeneic pancreatic tumor cells transfected with a GM-CSF gene in previously treated pancreatic cancer DT Le, E Lutz, JN Uram, EA Sugar, B Onners, S Solt, L Zheng, LA Diaz Jr, ... Journal of immunotherapy 36 (7), 382-389, 2013 | 618 | 2013 |
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays CA Iacobuzio-Donahue, A Maitra, M Olsen, AW Lowe, NT Van Heek, ... The American journal of pathology 162 (4), 1151-1162, 2003 | 578 | 2003 |
Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2 … JPH Machiels, RT Reilly, LA Emens, AM Ercolini, RY Lei, D Weintraub, ... Cancer research 61 (9), 3689-3697, 2001 | 552 | 2001 |
Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by ex Vivo Granulocyte-Macrophage Colony-stimulating Factor Gene Transfer JW Simons, EM Jaffee, CE Weber, HI Levitsky, WG Nelson, MA Carducci, ... Cancer research 57 (8), 1537-1546, 1997 | 541 | 1997 |
Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation ER Lutz, AA Wu, E Bigelow, R Sharma, G Mo, K Soares, S Solt, A Dorman, ... Cancer immunology research 2 (7), 616-631, 2014 | 528 | 2014 |
The determinants of tumour immunogenicity T Blankenstein, PG Coulie, E Gilboa, EM Jaffee Nature Reviews Cancer 12 (4), 307-313, 2012 | 509 | 2012 |
Galectin-3 Shapes Antitumor Immune Responses by Suppressing CD8+ T Cells via LAG-3 and Inhibiting Expansion of Plasmacytoid Dendritic Cells T Kouo, L Huang, AB Pucsek, M Cao, S Solt, T Armstrong, E Jaffee Cancer immunology research 3 (4), 412-423, 2015 | 507 | 2015 |
The immunodominant major histocompatibility complex class I-restricted antigen of a murine colon tumor derives from an endogenous retroviral gene product. AY Huang, PH Gulden, AS Woods, MC Thomas, CD Tong, WEI Wang, ... Proceedings of the National Academy of Sciences 93 (18), 9730-9735, 1996 | 499 | 1996 |
Recruitment of latent pools of high-avidity CD8+ T cells to the antitumor immune response AM Ercolini, BH Ladle, EA Manning, LW Pfannenstiel, TD Armstrong, ... The Journal of experimental medicine 201 (10), 1591-1602, 2005 | 479 | 2005 |
PD-1/PD-L1 blockade together with vaccine therapy facilitates effector T-cell infiltration into pancreatic tumors KC Soares, AA Rucki, AA Wu, K Olino, Q Xiao, Y Chai, A Wamwea, ... Journal of immunotherapy 38 (1), 1-11, 2015 | 455 | 2015 |
SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer A Blackford, OK Serrano, CL Wolfgang, G Parmigiani, S Jones, X Zhang, ... Clinical cancer research 15 (14), 4674-4679, 2009 | 449 | 2009 |