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Dr Rachael J Rigby
Dr Rachael J Rigby
Lecturer in Biomedicine, Lancaster University. MRC New Investigator
Verified email at lancaster.ac.uk - Homepage
Title
Cited by
Cited by
Year
High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse
S Ding, MM Chi, BP Scull, R Rigby, NMJ Schwerbrock, S Magness, ...
PloS one 5 (8), e12191, 2010
8552010
Characteristics of intestinal dendritic cells in inflammatory bowel diseases
AL Hart, HO Al-Hassi, RJ Rigby, SJ Bell, AV Emmanuel, SC Knight, ...
Gastroenterology 129 (1), 50-65, 2005
7242005
Migration and maturation of human colonic dendritic cells
SJ Bell, R Rigby, N English, SD Mann, SC Knight, MA Kamm, AJ Stagg
The Journal of Immunology 166 (8), 4958-4967, 2001
1982001
Suppressor of cytokine signaling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colon
RJ Rigby, JG Simmons, CJ Greenhalgh, WS Alexander, PK Lund
Oncogene 26 (33), 4833-4841, 2007
1942007
Expansion of intestinal stem cells associated with long-term adaptation following ileocecal resection in mice
CM Dekaney, JJ Fong, RJ Rigby, PK Lund, SJ Henning, MA Helmrath
American Journal of Physiology-Gastrointestinal and Liver Physiology 293 (5 …, 2007
1362007
Intestinal bacteria are necessary for doxorubicin-induced intestinal damage but not for doxorubicin-induced apoptosis
RJ Rigby, J Carr, K Orgel, SL King, PK Lund, CM Dekaney
Gut microbes 7 (5), 414-423, 2016
842016
Human gut dendritic cells drive aberrant gut-specific t-cell responses in ulcerative colitis, characterized by increased IL-4 production and loss of IL-22 and IFNγ
ER Mann, D Bernardo, SC Ng, RJ Rigby, HO Al-Hassi, J Landy, ...
Inflammatory bowel diseases 20 (12), 2299-2307, 2014
662014
A new animal model of postsurgical bowel inflammation and fibrosis: the effect of commensal microflora
RJ Rigby, MR Hunt, BP Scull, JG Simmons, KE Speck, MA Helmrath, ...
Gut 58 (8), 1104-1112, 2009
592009
Production of interleukin (IL)-10 and IL-12 by murine colonic dendritic cells in response to microbial stimuli
RJ Rigby, SC Knight, MA Kamm, AJ Stagg
Clinical & Experimental Immunology 139 (2), 245-256, 2005
592005
Loop ileostomy-mediated fecal stream diversion is associated with microbial dysbiosis
EL Beamish, J Johnson, EJ Shaw, NA Scott, A Bhowmick, RJ Rigby
Gut Microbes 8 (5), 467-478, 2017
572017
Cannabinoid-induced autophagy regulates suppressor of cytokine signaling-3 in intestinal epithelium
LC Koay, RJ Rigby, KL Wright
American Journal of Physiology-Gastrointestinal and Liver Physiology 307 (2 …, 2014
482014
Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileo-cecal resection
CM Dekaney, DC von Allmen, AP Garrison, RJ Rigby, PK Lund, ...
Surgery 144 (2), 174-181, 2008
442008
A population survey of dietary attitudes towards gluten
ID Croall, N Trott, A Rej, I Aziz, DJ O’Brien, HA George, MY Hossain, ...
Nutrients 11 (6), 1276, 2019
332019
Intestinal epithelial suppressor of cytokine signaling 3 enhances microbial-induced inflammatory tumor necrosis factor-α, contributing to epithelial barrier dysfunction
I Thagia, EJ Shaw, E Smith, KJ Else, RJ Rigby
American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (1 …, 2015
192015
Inflammation enhances resection-induced intestinal adaptive growth in IL-10 null mice
KE Speck, AP Garrison, RJ Rigby, DC von Allmen, PK Lund, MA Helmrath
Journal of Surgical Research 168 (1), 62-69, 2011
192011
Pathogenic bacteria stimulate colonic dendritic cells to produce pro-inflammatory IL-12 while the response to probiotic bacteria is to produce anti-inflammatory IL-10
R Rigby, MA Kamm, SC Knight, AL Hart, AJ Stagg
Gut 50, A70-A70, 2002
182002
What are the mechanisms of fibrosis in IBD?
KP Lund, RJ Rigby
Inflammatory bowel diseases 14 (suppl_2), S127-S128, 2008
112008
Intestinal epithelial suppressor of cytokine signaling 3 (SOCS3) impacts on mucosal homeostasis in a model of chronic inflammation
EJ Shaw, EE Smith, J Whittingham‐Dowd, MD Hodges, KJ Else, RJ Rigby
Immunity, Inflammation and Disease 5 (3), 336-345, 2017
102017
Hypothesis: bacterial induced inflammation disrupts the orderly progression of the stem cell hierarchy and has a role in the pathogenesis of breast cancer
AK Marwaha, JA Morris, RJ Rigby
Medical Hypotheses 136, 109530, 2020
92020
SOC-ing it to tumors: suppressors of cytokine signaling as tumor repressors
PK Lund, RJ Rigby
Gastroenterology 131 (1), 317-319, 2006
62006
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