Toxicity and management in CAR T-cell therapy CL Bonifant, HJ Jackson, RJ Brentjens, KJ Curran Molecular Therapy-Oncolytics 3, 2016 | 957 | 2016 |
JS-K, a Glutathione/Glutathione S-Transferase-activated Nitric Oxide Donor of the Diazeniumdiolate Class with Potent Antineoplastic Activity PJ Shami, JE Saavedra, LY Wang, CL Bonifant, BA Diwan, SV Singh, ... Molecular cancer therapeutics 2 (4), 409-417, 2003 | 237 | 2003 |
Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA JS Kim, C Lee, CL Bonifant, H Ressom, T Waldman Molecular and cellular biology 27 (2), 662-677, 2007 | 174 | 2007 |
Redirecting T cells to hematological malignancies with bispecific antibodies MP Velasquez, CL Bonifant, S Gottschalk Blood, The Journal of the American Society of Hematology 131 (1), 30-38, 2018 | 157 | 2018 |
Antitumor activity of JS-K [O 2-(2, 4-dinitrophenyl) 1-[(4-ethoxycarbonyl) piperazin-1-yl] diazen-1-ium-1, 2-diolate] and related O 2-aryl diazeniumdiolates in vitro and in vivo PJ Shami, JE Saavedra, CL Bonifant, J Chu, V Udupi, S Malaviya, BI Carr, ... Journal of medicinal chemistry 49 (14), 4356-4366, 2006 | 133 | 2006 |
The secondary amine/nitric oxide complex ion R2N [N (O) NO]-as nucleophile and leaving group in SNAr reactions JE Saavedra, A Srinivasan, CL Bonifant, J Chu, AP Shanklin, ... The Journal of organic chemistry 66 (9), 3090-3098, 2001 | 122 | 2001 |
Nitric oxide prodrugs and metallochemotherapeutics: JS-K and CB-3-100 enhance arsenic and cisplatin cytolethality by increasing cellular accumulation J Liu, C Li, W Qu, E Leslie, CL Bonifant, GS Buzard, JE Saavedra, ... Molecular cancer therapeutics 3 (6), 709-714, 2004 | 95 | 2004 |
CD123-engager T cells as a novel immunotherapeutic for acute myeloid leukemia CL Bonifant, A Szoor, D Torres, N Joseph, MP Velasquez, K Iwahori, ... Molecular Therapy 24 (9), 1615-1626, 2016 | 84 | 2016 |
Programmed cell death protein 1 activation preferentially inhibits CD28. CAR–T cells SN Zolov, SP Rietberg, CL Bonifant Cytotherapy 20 (10), 1259-1266, 2018 | 67 | 2018 |
Engineering CAR-NK cells to secrete IL-15 sustains their anti-AML functionality but is associated with systemic toxicities I Christodoulou, WJ Ho, A Marple, JW Ravich, A Tam, R Rahnama, ... Journal for immunotherapy of cancer 9 (12), 2021 | 63 | 2021 |
T cells expressing CD19-specific engager molecules for the immunotherapy of CD19-positive malignancies MP Velasquez, D Torres, K Iwahori, S Kakarla, C Arber, T Rodriguez-Cruz, ... Scientific reports 6 (1), 27130, 2016 | 62 | 2016 |
Time resolved absorption study of the reaction of hydroxyurea with sickle cell hemoglobin DB Kim-Shapiro, SB King, CL Bonifant, CP Kolibash, SK Ballas Biochimica et Biophysica Acta (BBA)-General Subjects 1380 (1), 64-74, 1998 | 52 | 1998 |
Epitope tagging of endogenous genes in diverse human cell lines JS Kim, C Bonifant, F Bunz, WS Lane, T Waldman Nucleic acids research 36 (19), e127-e127, 2008 | 47 | 2008 |
NHERFs, NEP, MAGUKs, and more: interactions that regulate PTEN CL Bonifant, JS Kim, T Waldman Journal of cellular biochemistry 102 (4), 878-885, 2007 | 35 | 2007 |
Nitrosylation of sickle cell hemoglobin by hydroxyurea Y Xu, CD Mull, CL Bonifant, G Yasaki, EC Palmer, H Shields, SK Ballas, ... The Journal of Organic Chemistry 63 (19), 6452-6453, 1998 | 33 | 1998 |
Impact of high disease burden on survival in pediatric patients with B-ALL treated with tisagenlecleucel JW Ravich, S Huang, Y Zhou, P Brown, CH Pui, H Inaba, C Cheng, ... Transplantation and cellular therapy 28 (2), 73. e1-73. e9, 2022 | 23 | 2022 |
Glycoprotein targeted CAR-NK cells for the treatment of SARS-CoV-2 infection I Christodoulou, R Rahnama, JW Ravich, J Seo, SN Zolov, AN Marple, ... Frontiers in immunology 12, 763460, 2021 | 18 | 2021 |
The art and science of selecting a CD123-specific chimeric antigen receptor for clinical testing JM Riberdy, S Zhou, F Zheng, YI Kim, J Moore, A Vaidya, RE Throm, ... Molecular Therapy-Methods & Clinical Development 18, 571-581, 2020 | 18 | 2020 |
Chemistry of the Diazeniumdiolates: Z ⇌ E Isomerism YN Wang, DS Bohle, CL Bonifant, GN Chmurny, JR Collins, KM Davies, ... Journal of the American Chemical Society 127 (15), 5388-5395, 2005 | 18 | 2005 |
Improving CAR T-cells: The next generation AH Marple, CL Bonifant, NN Shah Seminars in Hematology 57 (3), 115-121, 2020 | 17 | 2020 |