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Alexios N. Matralis
Alexios N. Matralis
Biomedical Sciences Research Center "Alexander Fleming"
Verified email at fleming.gr
Title
Cited by
Cited by
Year
Novel benzoxazine and benzothiazine derivatives as multifunctional antihyperlipidemic agents
AN Matralis, MG Katselou, A Nikitakis, AP Kourounakis
Journal of medicinal chemistry 54 (15), 5583-5591, 2011
632011
Human isoprenoid synthase enzymes as therapeutic targets
J Park, AN Matralis, AM Berghuis, YS Tsantrizos
Frontiers in chemistry 2, 50, 2014
542014
Design of novel potent antihyperlipidemic agents with antioxidant/anti-inflammatory properties: Exploiting phenothiazine’s strong antioxidant activity
AN Matralis, AP Kourounakis
Journal of medicinal chemistry 57 (6), 2568-2581, 2014
472014
Design of more potent squalene synthase inhibitors with multiple activities
AP Kourounakis, AN Matralis, A Nikitakis
Bioorganic & medicinal chemistry 18 (21), 7402-7412, 2010
402010
Squalene synthase inhibitors: An update on the search for new antihyperlipidemic and antiatherosclerotic agents
A P Kourounakis, M G Katselou, A N Matralis, E M Ladopoulou, ...
Current medicinal chemistry 18 (29), 4418-4439, 2011
382011
Development and therapeutic potential of autotaxin small molecule inhibitors: From bench to advanced clinical trials
AN Matralis, A Afantitis, V Aidinis
Medicinal research reviews 39 (3), 976-1013, 2019
342019
Antihyperlipidemic morpholine derivatives with antioxidant activity: An investigation of the aromatic substitution
EM Ladopoulou, AN Matralis, A Nikitakis, AP Kourounakis
Bioorganic & medicinal chemistry 23 (21), 7015-7023, 2015
342015
Water-Soluble Stoichiometric Polyelectrolyte Complexes Based on Cationic Comb-Type Copolymers
A Matralis, M Sotiropoulou, G Bokias, G Staikos
Macromolecular Chemistry and Physics 207 (12), 1018-1025, 2005
292005
Multi-target drug design approaches for multifactorial diseases: From neurodegenerative to cardiovascular applications
MG Katselou, AN Matralis, AP Kourounakis
Current medicinal chemistry 21 (24), 2743-2787, 2014
272014
Antioxidant Activity of Newly Synthesized 2, 7‐Diazaphenothiazines
B Morak‐Młodawska, K Pluta, AN Matralis, AP Kourounakis
Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2010
252010
Pharmacophore mapping of thienopyrimidine-based monophosphonate (ThP-MP) inhibitors of the human farnesyl pyrophosphate synthase
J Park, CY Leung, AN Matralis, CM Lacbay, M Tsakos, ...
Journal of Medicinal Chemistry 60 (5), 2119-2134, 2017
222017
Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites
AN Matralis, A Malik, M Penzo, I Moreno, MJ Almela, I Camino, B Crespo, ...
Journal of medicinal chemistry 62 (20), 9217-9235, 2019
182019
New Multifunctional Di-tert-butylphenoloctahydro(pyrido/benz)oxazine Derivatives with Antioxidant, Antihyperlipidemic, and Antidiabetic Action
E Ladopoulou, AN Matralis, AP Kourounakis
Journal of Medicinal Chemistry 56 (8), 3330-3338, 2013
182013
Evaluation of two novel antioxidants with differential effects on curcumin-induced apoptosis in C2 skeletal myoblasts; involvement of JNKs
M Peleli, IK Aggeli, AN Matralis, AP Kourounakis, I Beis, C Gaitanaki
Bioorganic & Medicinal Chemistry 23 (3), 390-400, 2015
142015
Developing potential agents against atherosclerosis: design, synthesis and pharmacological evaluation of novel dual inhibitors of oxidative stress and Squalene Synthase activity
MG Katselou, AN Matralis, AP Kourounakis
European Journal of Medicinal Chemistry 138, 748-760, 2017
122017
Molecular tools that block maturation of the nuclear lamin A and decelerate cancer cell migration
AN Matralis, D Xanthopoulos, G Huot, S Lopes-Paciencia, C Cole, ...
Bioorganic & Medicinal Chemistry 26 (20), 5547-5554, 2018
112018
Targeting the malaria parasite cGMP-dependent protein kinase to develop new drugs
DA Baker, AN Matralis, SA Osborne, JM Large, M Penzo
Frontiers in Microbiology 11, 602803, 2020
92020
Optimizing the pharmacological profile of new bifunctional antihyperlipidemic/antioxidant morpholine derivatives
AN Matralis, AP Kourounakis
ACS medicinal chemistry letters 10 (1), 98-104, 2018
72018
Balancing antioxidant, hypolipidemic and anti-inflammatory activity in a single agent: The example of 2-hydroxy-2-substituted morpholine, 1, 4-benzoxazine and 1, 4 …
A N Matralis, EI Bavavea, S Incerpi, J Z Pedersen, A P Kourounakis
Current medicinal chemistry 24 (12), 1214-1227, 2017
52017
Synthesis of Benzothiophene‐Containing 10‐and 11‐Membered Cyclic Phostones
AN Matralis, YS Tsantrizos
European Journal of Organic Chemistry 2016 (22), 3728-3736, 2016
42016
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