Frank Hirth
Frank Hirth
Reader of Evolutionary Neuroscience, King's College London
Verified email at - Homepage
Cited by
Cited by
Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic
YB Lee, HJ Chen, JN Peres, J Gomez-Deza, J Attig, M Štalekar, ...
Cell reports 5 (5), 1178-1186, 2013
The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila
B Bello, H Reichert, F Hirth
Development 133 (14), 2639-2648, 2006
Deep homology of arthropod central complex and vertebrate basal ganglia
NJ Strausfeld, F Hirth
Science 340 (6129), 157-161, 2013
Developmental defects in brain segmentation caused by mutations of the homeobox genes orthodenticle and empty spiracles in Drosophila
F Hirth, S Therianos, T Loop, WJ Gehring, H Reichert, ...
Neuron 15 (4), 769-778, 1995
A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis
BC Bello, F Hirth, AP Gould
Neuron 37 (2), 209-219, 2003
Drosophila melanogaster in the study of human neurodegeneration
F Hirth
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2010
An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila
F Hirth, L Kammermeier, E Frei, U Walldorf, M Noll, H Reichert
Development 130 (11), 2365-2373, 2003
Conserved genetic programs in insect and mammalian brain development
F Hirth, H Reichert
BioEssays 21 (8), 677-684, 1999
Equivalence of the fly orthodenticle gene and the human OTX genes in embryonic brain development of Drosophila
S Leuzinger, F Hirth, D Gerlich, D Acampora, A Simeone, WJ Gehring, ...
Development 125 (9), 1703-1710, 1998
Homeotic gene action in embryonic brain development of Drosophila
F Hirth, B Hartmann, H Reichert
Development 125 (9), 1579-1589, 1998
The dopaminergic system in the aging brain of Drosophila
KE White, DM Humphrey, F Hirth
Frontiers in neuroscience 4, 205, 2010
Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes
DC Diaper, Y Adachi, B Sutcliffe, DM Humphrey, CJH Elliott, A Stepto, ...
Human molecular genetics 22 (8), 1539-1557, 2013
Mechanisms of α-synuclein induced synaptopathy in Parkinson's disease
JC Bridi, F Hirth
Frontiers in neuroscience 12, 80, 2018
Embryonic development of the Drosophila brain: formation of commissural and descending pathways
S Therianos, S Leuzinger, F Hirth, CS Goodman, H Reichert
Development 121 (11), 3849-3860, 1995
Differential expression and function of the Drosophila Pax6 genes eyeless and twin of eyeless in embryonic central nervous system development
L Kammermeier, R Leemans, F Hirth, S Flister, U Wenger, U Walldorf, ...
Mechanisms of development 103 (1-2), 71-78, 2001
Quantitative transcript imaging in normal and heat-shocked Drosophila embryos by using high-density oligonucleotide arrays
R Leemans, B Egger, T Loop, L Kammermeier, H He, B Hartmann, ...
Proceedings of the National Academy of Sciences 97 (22), 12138-12143, 2000
Asymmetric stem cell division in development and cancer
E Caussinus, F Hirth
Asymmetric Cell Division, 205-225, 2007
Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD
DC Diaper, Y Adachi, L Lazarou, M Greenstein, FA Simoes, ...
Human molecular genetics 22 (19), 3883-3893, 2013
Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila
DM Humphrey, RB Parsons, ZN Ludlow, T Riemensperger, G Esposito, ...
Human molecular genetics 21 (12), 2698-2712, 2012
TDP-43 Loss-of-Function Causes Neuronal Loss Due to Defective Steroid Receptor-Mediated Gene Program Switching in Drosophila
LV Broeck, M Naval-Sánchez, Y Adachi, D Diaper, P Dourlen, J Chapuis, ...
Cell reports 3 (1), 160-172, 2013
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