An acquired vulnerability of drug-resistant melanoma with therapeutic potential L Wang, RL de Oliveira, S Huijberts, E Bosdriesz, N Pencheva, D Brunen, ... Cell 173 (6), 1413-1425. e14, 2018 | 287 | 2018 |
How fast‐growing bacteria robustly tune their ribosome concentration to approximate growth‐rate maximization E Bosdriesz, D Molenaar, B Teusink, FJ Bruggeman The FEBS journal 282 (10), 2029-2044, 2015 | 243 | 2015 |
MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models Z Xue, DJ Vis, A Bruna, T Sustic, S van Wageningen, AS Batra, ... Cell research 28 (7), 719-729, 2018 | 111 | 2018 |
Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours JM Fernandes Neto, E Nadal, E Bosdriesz, SN Ooft, L Farre, C McLean, ... Nature communications 11 (1), 3157, 2020 | 80 | 2020 |
How biochemical constraints of cellular growth shape evolutionary adaptations in metabolism J Berkhout, E Bosdriesz, E Nikerel, D Molenaar, D de Ridder, B Teusink, ... Genetics 194 (2), 505-512, 2013 | 49 | 2013 |
Evolutionary pressures on microbial metabolic strategies in the chemostat MT Wortel, E Bosdriesz, B Teusink, FJ Bruggeman Scientific reports 6 (1), 29503, 2016 | 47 | 2016 |
Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux E Bosdriesz, MT Wortel, JR Haanstra, MJ Wagner, P De La Torre Cortes, ... Scientific reports 8 (1), 1-9, 2018 | 45 | 2018 |
A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers T Šuštić, S van Wageningen, E Bosdriesz, RJD Reid, J Dittmar, C Lieftink, ... Genome Medicine 10, 1-13, 2018 | 41 | 2018 |
Modelling signalling networks from perturbation data M Dorel, B Klinger, T Gross, A Sieber, A Prahallad, E Bosdriesz, ... Bioinformatics 34 (23), 4079-4086, 2018 | 36 | 2018 |
Binding proteins enhance specific uptake rate by increasing the substrate–transporter encounter rate E Bosdriesz, S Magnúsdóttir, FJ Bruggeman, B Teusink, D Molenaar The FEBS Journal 282 (12), 2394-2407, 2015 | 28 | 2015 |
A system-wide approach to monitor responses to synergistic BRAF and EGFR inhibition in colorectal cancer cells A Ressa, E Bosdriesz, J De Ligt, S Mainardi, G Maddalo, A Prahallad, ... Molecular & Cellular Proteomics 17 (10), 1892-1908, 2018 | 17 | 2018 |
Comparative Network Reconstruction using mixed integer programming E Bosdriesz, A Prahallad, B Klinger, A Sieber, A Bosma, R Bernards, ... Bioinformatics 34 (17), i997-i1004, 2018 | 12 | 2018 |
RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS-mutant colorectal cancer T Šuštić, E Bosdriesz, S van Wageningen, LFA Wessels, R Bernards Translational oncology 13 (2), 201-211, 2020 | 7 | 2020 |
Identifying biomarkers of anti-cancer drug synergy using multi-task learning N Aben, JR de Ruiter, E Bosdriesz, Y Kim, G Bounova, DJ Vis, ... bioRxiv, 243568, 2018 | 2 | 2018 |
Identifying mutant-specific multi-drug combinations using comparative network reconstruction E Bosdriesz, JMF Neto, A Sieber, R Bernards, N Blüthgen, LFA Wessels Iscience 25 (8), 2022 | 1 | 2022 |
Darwin s invisible hand E Bosdriesz | 1 | 2015 |
Reconstructing and comparing signal transduction networks from single cell protein quantification data T Stohn, R van Eijl, KW Mulder, LFA Wessels, E Bosdriesz bioRxiv, 2024.03. 29.587331, 2024 | | 2024 |
VU Research Portal M Dorel, B Klinger, T Gross, A Sieber, A Prahallad, E Bosdriesz, ... Bioinformatics 34 (23), 4079-4086, 2018 | | 2018 |