Prati
Elena Bianchetti
Elena Bianchetti
LEXEO therapeutics
Potvrđena adresa e-pošte na columbia.edu
Naslov
Citirano
Citirano
Godina
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models
TTT Nguyen, Y Zhang, E Shang, C Shu, C Torrini, J Zhao, E Bianchetti, ...
The Journal of clinical investigation 130 (7), 3699-3716, 2020
1152020
Induction of synthetic lethality in IDH1-mutated gliomas through inhibition of Bcl-xL
G Karpel-Massler, CT Ishida, E Bianchetti, Y Zhang, C Shu, T Tsujiuchi, ...
Nature communications 8 (1), 1067, 2017
1122017
Metabolic reprogramming by dual AKT/ERK inhibition through imipridones elicits unique vulnerabilities in glioblastoma
CT Ishida, Y Zhang, E Bianchetti, C Shu, TTT Nguyen, G Kleiner, ...
Clinical Cancer Research 24 (21), 5392-5406, 2018
742018
Inhibition of mitochondrial matrix chaperones and antiapoptotic Bcl-2 family proteins empower antitumor therapeutic responses
G Karpel-Massler, CT Ishida, E Bianchetti, C Shu, R Perez-Lorenzo, ...
Cancer research 77 (13), 3513-3526, 2017
642017
Stasimon contributes to the loss of sensory synapses and motor neuron death in a mouse model of spinal muscular atrophy
CM Simon, M Van Alstyne, F Lotti, E Bianchetti, S Tisdale, DM Watterson, ...
Cell reports 29 (12), 3885-3901. e5, 2019
462019
Combined HDAC and bromodomain protein inhibition reprograms tumor cell metabolism and elicits synthetic lethality in glioblastoma
Y Zhang, CT Ishida, W Ishida, SFL Lo, J Zhao, C Shu, E Bianchetti, ...
Clinical Cancer Research 24 (16), 3941-3954, 2018
422018
BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma.
SMD Ishida CT, Bianchetti E, Shu C, Halatsch ME, Westhoff MA, Karpel-Massler G
Oncotarget, 2017
392017
ATF3 is a novel nuclear marker for migrating ependymal stem cells in the rat spinal cord
M Mladinic, E Bianchetti, A Dekanic, GL Mazzone, A Nistri
Stem Cell Research 12 (3), 815-827, 2014
392014
MET inhibition elicits PGC1α-dependent metabolic reprogramming in glioblastoma
Y Zhang, TTT Nguyen, E Shang, A Mela, N Humala, A Mahajan, J Zhao, ...
Cancer research 80 (1), 30-43, 2020
372020
Activation of LXR β inhibits tumor respiration and is synthetically lethal with Bcl‐xL inhibition
TTT Nguyen, CT Ishida, E Shang, C Shu, C Torrini, Y Zhang, E Bianchetti, ...
EMBO Molecular Medicine 11 (10), e10769, 2019
362019
Mechanisms underlying cell death in ischemia-like damage to the rat spinal cord in vitro
E Bianchetti, M Mladinic, A Nistri
Cell death & disease 4 (7), e707-e707, 2013
292013
Activation of LXR receptors and inhibition of TRAP1 causes synthetic lethality in solid tumors
TTT Nguyen, CT Ishida, E Shang, C Shu, E Bianchetti, G Karpel-Massler, ...
Cancers 11 (6), 788, 2019
222019
Dual Inhibition of Bcl-2/Bcl-xL and XPO1 is synthetically lethal in glioblastoma model systems
E Shang, Y Zhang, C Shu, CT Ishida, E Bianchetti, MA Westhoff, ...
Scientific Reports 8 (1), 15383, 2018
192018
Usp9X regulates cell death in malignant peripheral nerve sheath tumors
E Bianchetti, SJ Bates, SL Carroll, MD Siegelin, KA Roth
Scientific reports 8 (1), 17390, 2018
172018
The volatile anesthetic methoxyflurane protects motoneurons against excitotoxicity in an in vitro model of rat spinal cord injury
A Shabbir, E Bianchetti, A Nistri
Neuroscience 285, 269-280, 2015
172015
Unusual increase in lumbar network excitability of the rat spinal cord evoked by the PARP-1 inhibitor PJ-34 through inhibition of glutamate uptake
SE Nasrabady, A Kuzhandaivel, A Akrami, E Bianchetti, M Milanese, ...
Neuropharmacology 63 (3), 415-426, 2012
172012
Role of HSP70 in motoneuron survival after excitotoxic stress in a rat spinal cord injury model in vitro
A Shabbir, E Bianchetti, R Cargonja, A Petrovic, M Mladinic, K Pilipović, ...
European Journal of Neuroscience 42 (12), 3054-3065, 2015
162015
Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma
Y Zhang, CT Ishida, C Shu, G Kleiner, MJ Sanchez-Quintero, E Bianchetti, ...
Scientific Reports 8 (1), 7373, 2018
122018
BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma. Oncotarget 8, 29558–29573
CT Ishida, E Bianchetti, C Shu, ME Halatsch, MA Westhoff, ...
72017
RAB38 facilitates energy metabolism and counteracts cell death in glioblastoma cells
E Bianchetti, SJ Bates, TTT Nguyen, MD Siegelin, KA Roth
Cells 10 (7), 1643, 2021
52021
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