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Nancy Ratner
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Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.
CI Brannan, AS Perkins, KS Vogel, N Ratner, ML Nordlund, SW Reid, ...
Genes & development 8 (9), 1019-1029, 1994
7571994
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.
CI Brannan, AS Perkins, KS Vogel, N Ratner, ML Nordlund, SW Reid, ...
Genes & development 8 (9), 1019-1029, 1994
7571994
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis
JE DeClue, AG Papageorge, JA Fletcher, SR Diehl, N Ratner, WC Vass, ...
Cell 69 (2), 265-273, 1992
7091992
Activity of selumetinib in neurofibromatosis type 1–related plexiform neurofibromas
E Dombi, A Baldwin, LJ Marcus, MJ Fisher, B Weiss, AR Kim, P Whitcomb, ...
New England Journal of Medicine 375 (26), 2550-2560, 2016
6062016
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin‐based motility
G Morfini, G Szebenyi, R Elluru, N Ratner, ST Brady
The EMBO journal, 2002
5102002
A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor
N Ratner, SJ Miller
Nature Reviews Cancer 15 (5), 290-301, 2015
4642015
The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling
RJ Shaw, JG Paez, M Curto, A Yaktine, WM Pruitt, I Saotome, JP O'Bryan, ...
Developmental cell 1 (1), 63-72, 2001
4072001
The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes
MM Daston, H Scrable, M Nordlund, AK Sturbaum, LM Nissen, N Ratner
Neuron 8 (3), 415-428, 1992
3891992
MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors
WJ Jessen, SJ Miller, E Jousma, J Wu, TA Rizvi, ME Brundage, D Eaves, ...
The Journal of clinical investigation 123 (1), 340-347, 2013
3482013
Cognitive function and academic performance in neurofibrornatosis 1: Consensus statement from the NF1 Cognitive Disorders Task Force
KN North, V Riccardi, C Samango-Sprouse, R Ferner, B Moore, E Legius, ...
Neurology 48 (4), 1121-1127, 1997
3381997
Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/– mast cells
Y Feng-Chun, DA Ingram, S Chen, CM Hingtgen, N Ratner, KR Monk, ...
The Journal of clinical investigation 112 (12), 1851-1861, 2003
2542003
Mechanisms and roles of axon-Schwann cell interactions
G Corfas, MO Velardez, CP Ko, N Ratner, E Peles
Journal of Neuroscience 24 (42), 9250-9260, 2004
2532004
Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells
J Wu, JP Williams, TA Rizvi, JJ Kordich, D Witte, D Meijer, ...
Cancer cell 13 (2), 105-116, 2008
2322008
Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues
SJ Miller, F Rangwala, J Williams, P Ackerman, S Kong, AG Jegga, ...
Cancer research 66 (5), 2584-2591, 2006
2202006
Epidermal growth factor receptor expression in neurofibromatosis type 1–related tumors and NF1 animal models
JE DeClue, S Heffelfinger, G Benvenuto, B Ling, S Li, W Rui, WC Vass, ...
The Journal of clinical investigation 105 (9), 1233-1241, 2000
2112000
Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells
PD Pelton, LS Sherman, TA Rizvi, MA Marchionni, P Wood, RA Friedman, ...
Oncogene 17 (17), 2195-2209, 1998
2051998
A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation.
N Ratner, RP Bunge, L Glaser
The Journal of cell biology 101 (3), 744-754, 1985
2011985
Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria
SR Plotkin, JO Blakeley, DG Evans, CO Hanemann, TJM Hulsebos, ...
American journal of medical genetics Part A 161 (3), 405-416, 2013
1912013
S100 is present in developing chicken neurons and schwann cell and promotes motor neuron survival in vivo
A Bhattacharyya, RW Oppenheim, D Prevette, BW Moore, R Brackenbury, ...
Journal of neurobiology 23 (4), 451-466, 1992
1891992
Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts
LS Sherman, R Atit, T Rosenbaum, AD Cox, N Ratner
Journal of Biological Chemistry 275 (39), 30740-30745, 2000
1792000
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Articles 1–20