| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13160* | 2021 |
| Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases A Cuadrado, AI Rojo, G Wells, JD Hayes, SP Cousin, WL Rumsey, ... Nature reviews Drug discovery 18 (4), 295-317, 2019 | 961 | 2019 |
| Clinical relevance of biomarkers of oxidative stress J Frijhoff, PG Winyard, N Zarkovic, SS Davies, R Stocker, D Cheng, ... Antioxidants & redox signaling 23 (14), 1144-1170, 2015 | 857 | 2015 |
| Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical … D Martin, AI Rojo, M Salinas, R Diaz, G Gallardo, J Alam, ... Journal of Biological Chemistry 279 (10), 8919-8929, 2004 | 823 | 2004 |
| SCF/β-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner P Rada, AI Rojo, S Chowdhry, M McMahon, JD Hayes, A Cuadrado Molecular and cellular biology, 2011 | 786 | 2011 |
| Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity S Chowdhry, Y Zhang, M McMahon, C Sutherland, A Cuadrado, ... Oncogene 32 (32), 3765-3781, 2013 | 642 | 2013 |
| The transcription factor Nrf2 is a therapeutic target against brain inflammation NG Innamorato, AI Rojo, AJ García-Yagüe, M Yamamoto, ... The Journal of Immunology 181 (1), 680-689, 2008 | 546 | 2008 |
| Transcription factor NRF2 as a therapeutic target for chronic diseases: a systems medicine approach A Cuadrado, G Manda, A Hassan, MJ Alcaraz, C Barbas, A Daiber, ... Pharmacological reviews 70 (2), 348-383, 2018 | 538 | 2018 |
| Glycogen synthase kinase-3β inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2 M Salazar, AI Rojo, D Velasco, RM de Sagarra, A Cuadrado Journal of Biological Chemistry 281 (21), 14841-14851, 2006 | 535 | 2006 |
| Activators and inhibitors of NRF2: a review of their potential for clinical development N Robledinos-Antón, R Fernández-Ginés, G Manda, A Cuadrado Oxidative medicine and cellular longevity 2019, 2019 | 477 | 2019 |
| Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimer's disease AM Martín-Moreno, D Reigada, BG Ramírez, R Mechoulam, N Innamorato, ... Molecular pharmacology 79 (6), 964-973, 2011 | 415 | 2011 |
| Activation of Akt/Protein Kinase B by G protein-coupled receptors: a role for α and βγ subunits of heterotrimeric g proteins acting through phosphatidylinositol-3-OH kinaseγ C Murga, L Laguinge, R Wetzker, A Cuadrado, JS Gutkind Journal of Biological Chemistry 273 (30), 19080-19085, 1998 | 405 | 1998 |
| Inflammation in Parkinson’s disease: mechanisms and therapeutic implications M Pajares, A I. Rojo, G Manda, L Boscá, A Cuadrado Cells 9 (7), 1687, 2020 | 383 | 2020 |
| Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease AI Rojo, NG Innamorato, AM Martín‐Moreno, ML De Ceballos, ... Glia 58 (5), 588-598, 2010 | 377 | 2010 |
| Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis P Rada, AI Rojo, N Evrard-Todeschi, NG Innamorato, A Cotte, T Jaworski, ... Molecular and cellular biology 32 (17), 3486-3499, 2012 | 355 | 2012 |
| Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes M Pajares, N Jiménez-Moreno, ÁJ García-Yagüe, M Escoll, ... Autophagy 12 (10), 1902-1916, 2016 | 345 | 2016 |
| Transcription factors NRF2 and NF-κB are coordinated effectors of the Rho family, GTP-binding protein RAC1 during inflammation A Cuadrado, Z Martín-Moldes, J Ye, I Lastres-Becker Journal of Biological Chemistry 289 (22), 15244-15258, 2014 | 324 | 2014 |
| Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism A Jazwa, AI Rojo, NG Innamorato, M Hesse, J Fernández-Ruiz, ... Antioxidants & redox signaling 14 (12), 2347-2360, 2011 | 323 | 2011 |
| European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach, T Kietzmann, ... Redox biology 13, 94-162, 2017 | 315 | 2017 |
| Redox control of microglial function: molecular mechanisms and functional significance AI Rojo, G McBean, M Cindric, J Egea, MG López, P Rada, N Zarkovic, ... Antioxidants & redox signaling 21 (12), 1766-1801, 2014 | 314 | 2014 |
