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Isaac Kohane
Isaac Kohane
Harvard Medical School, Children's Hospital, Brigham and Women's Hospital
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network Tissue source sites: Duke University ...
Nature 455 (7216), 1061-1068, 2008
64722008
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
ME Patti, AJ Butte, S Crunkhorn, K Cusi, R Berria, S Kashyap, Y Miyazaki, ...
Proceedings of the National Academy of Sciences 100 (14), 8466-8471, 2003
22172003
Gene regulation and DNA damage in the ageing human brain
T Lu, Y Pan, SY Kao, C Li, I Kohane, J Chan, BA Yankner
Nature 429 (6994), 883-891, 2004
19342004
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668-681, 2018
16572018
Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements
AJ Butte, IS Kohane
Biocomputing 2000, 418-429, 1999
13191999
Machine learning in medicine
A Rajkomar, J Dean, I Kohane
New England Journal of Medicine 380 (14), 1347-1358, 2019
12522019
A mega-analysis of genome-wide association studies for major depressive disorder
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium
Molecular psychiatry 18 (4), 2013
11352013
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
SL Carter, AC Eklund, IS Kohane, LN Harris, Z Szallasi
Nature genetics 38 (9), 1043-1048, 2006
11102006
Toward precision medicine: building a knowledge network for biomedical research and a new taxonomy of disease
National Research Council
National Academies Press, 2011
9732011
Big data and machine learning in health care
AL Beam, IS Kohane
Jama 319 (13), 1317-1318, 2018
9282018
Artificial intelligence in healthcare
KH Yu, AL Beam, IS Kohane
Nature biomedical engineering 2 (10), 719-731, 2018
8882018
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)
SN Murphy, G Weber, M Mendis, V Gainer, HC Chueh, S Churchill, ...
Journal of the American Medical Informatics Association 17 (2), 124-130, 2010
8852010
Discovering statistically significant pathways in expression profiling studies
L Tian, SA Greenberg, SW Kong, J Altschuler, IS Kohane, PJ Park
Proceedings of the National Academy of Sciences 102 (38), 13544-13549, 2005
7882005
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks
AJ Butte, P Tamayo, D Slonim, TR Golub, IS Kohane
Proceedings of the National Academy of Sciences 97 (22), 12182-12186, 2000
7572000
Human disease classification in the postgenomic era: a complex systems approach to human pathobiology
J Loscalzo, I Kohane, AL Barabasi
Molecular systems biology 3 (1), 124, 2007
6222007
Analysis of matched mRNA measurements from two different microarray technologies
WP Kuo, TK Jenssen, AJ Butte, L Ohno-Machado, IS Kohane
Bioinformatics 18 (3), 405-412, 2002
6012002
Distinctive patterns of microRNA expression in primary muscular disorders
I Eisenberg, A Eran, I Nishino, M Moggio, C Lamperti, AA Amato, ...
Proceedings of the National Academy of Sciences 104 (43), 17016-17021, 2007
5502007
Cluster analysis of gene expression dynamics
MF Ramoni, P Sebastiani, IS Kohane
Proceedings of the National Academy of Sciences 99 (14), 9121-9126, 2002
5452002
The co-morbidity burden of children and young adults with autism spectrum disorders
IS Kohane, A McMurry, G Weber, D MacFadden, L Rappaport, L Kunkel, ...
PloS one 7 (4), e33224, 2012
5402012
Genetic misdiagnoses and the potential for health disparities
AK Manrai, BH Funke, HL Rehm, MS Olesen, BA Maron, P Szolovits, ...
New England Journal of Medicine 375 (7), 655-665, 2016
5162016
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