Interleukin-6 signaling drives fibrosis in unresolved inflammation CA Fielding, GW Jones, RM McLoughlin, L McLeod, VJ Hammond, ... Immunity 40 (1), 40-50, 2014 | 367 | 2014 |
Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway TC Cheung, IR Humphreys, KG Potter, PS Norris, HM Shumway, BR Tran, ... Proceedings of the National Academy of Sciences 102 (37), 13218-13223, 2005 | 270 | 2005 |
Potential role of oral rinses targeting the viral lipid envelope in SARS-CoV-2 infection VB O’Donnell, D Thomas, R Stanton, JY Maillard, RC Murphy, SA Jones, ... Function 1 (1), zqaa002, 2020 | 199 | 2020 |
Cytomegalovirus exploits IL-10–mediated immune regulation in the salivary glands IR Humphreys, C De Trez, A Kinkade, CA Benedict, M Croft, CF Ware The Journal of experimental medicine 204 (5), 1217-1225, 2007 | 166 | 2007 |
A role for dendritic cells in the dissemination of mycobacterial infection IR Humphreys, GR Stewart, DJ Turner, J Patel, D Karamanou, ... Microbes and Infection 8 (5), 1339-1346, 2006 | 155 | 2006 |
Novel viral vectors in infectious diseases IR Humphreys, S Sebastian Immunology 153 (1), 1-9, 2018 | 153 | 2018 |
A critical role for OX40 in T cell–mediated immunopathology during lung viral infection IR Humphreys, G Walzl, L Edwards, A Rae, S Hill, T Hussell The Journal of experimental medicine 198 (8), 1237-1242, 2003 | 151 | 2003 |
OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T Cells: A CD4-dependent mechanism IR Humphreys, A Loewendorf, C De Trez, K Schneider, CA Benedict, ... The Journal of immunology 179 (4), 2195-2202, 2007 | 116 | 2007 |
Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction CJ Greenhill, GW Jones, MA Nowell, Z Newton, AK Harvey, AN Moideen, ... Arthritis research & therapy 16, 1-10, 2014 | 111 | 2014 |
The stress‐responsive chaperone α‐crystallin 2 is required for pathogenesis of Mycobacterium tuberculosis GR Stewart, SM Newton, KA Wilkinson, IR Humphreys, HN Murphy, ... Molecular Microbiology 55 (4), 1127-1137, 2005 | 93 | 2005 |
Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV MA Stacey, M Marsden, S Clare, G Dolton, G Stack, E Jones, ... Cell host & microbe 15 (4), 471-483, 2014 | 85 | 2014 |
Ecophylogenetics clarifies the evolutionary association between mammals and their gut microbiota CA Gaulke, HK Arnold, IR Humphreys, SW Kembel, JP O’Dwyer, ... MBio 9 (5), 10.1128/mbio. 01348-18, 2018 | 78 | 2018 |
Innate imprinting by the modified heat-labile toxin of Escherichia coli (LTK63) provides generic protection against lung infectious disease AE Williams, L Edwards, IR Humphreys, R Snelgrove, A Rae, R Rappuoli, ... The Journal of Immunology 173 (12), 7435-7443, 2004 | 77 | 2004 |
Biphasic role of 4‐1BB in the regulation of mouse cytomegalovirus‐specific CD8+ T cells IR Humphreys, SW Lee, M Jones, A Loewendorf, E Gostick, DA Price, ... European journal of immunology 40 (10), 2762-2768, 2010 | 73 | 2010 |
IL-10 restricts memory T cell inflation during cytomegalovirus infection M Jones, K Ladell, KK Wynn, MA Stacey, MF Quigley, E Gostick, DA Price, ... The Journal of Immunology 185 (6), 3583-3592, 2010 | 72 | 2010 |
The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T-cell immunity JP Twohig, M Marsden, SM Cuff, JR Ferdinand, AM Gallimore, WV Perks, ... FASEB journal: official publication of the Federation of American Societies …, 2012 | 71 | 2012 |
Characterization in mice of the immunological properties of five allergenic acid anhydrides RJ Dearman, EV Warbrick, IR Humphreys, I Kimber Journal of Applied Toxicology: An International Journal 20 (3), 221-230, 2000 | 66 | 2000 |
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases A Singhania, CM Graham, L Gabryšová, L Moreira-Teixeira, ... Nature communications 10 (1), 2887, 2019 | 64 | 2019 |
IL-10 restricts activation-induced death of NK cells during acute murine cytomegalovirus infection MA Stacey, M Marsden, ECY Wang, GWG Wilkinson, IR Humphreys The Journal of Immunology 187 (6), 2944-2952, 2011 | 64 | 2011 |
Interferon-induced transmembrane protein 1 restricts replication of viruses that enter cells via the plasma membrane SE Smith, DC Busse, S Binter, S Weston, C Diaz Soria, BM Laksono, ... Journal of virology 93 (6), 10.1128/jvi. 02003-18, 2019 | 61 | 2019 |