|Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies|
W Zhou, JB Nielsen, LG Fritsche, R Dey, ME Gabrielsen, BN Wolford, ...
Nature genetics 50 (9), 1335-1341, 2018
|Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study|
AN Kho, MG Hayes, L Rasmussen-Torvik, JA Pacheco, WK Thompson, ...
Journal of the American Medical Informatics Association 19 (2), 212-218, 2012
|Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins|
I Postmus, S Trompet, HA Deshmukh, MR Barnes, X Li, HR Warren, ...
Nature communications 5 (1), 1-10, 2014
|Extracting research-quality phenotypes from electronic health records to support precision medicine|
WQ Wei, JC Denny
Genome Medicine 7 (41), 2015
|Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care|
MK DeGorter, RG Tirona, UI Schwarz, YH Choi, GK Dresser, N Suskin, ...
Circulation: Cardiovascular Genetics 6 (4), 400-408, 2013
|Trans-ethnic association study of blood pressure determinants in over 750,000 individuals|
A Giri, JN Hellwege, JM Keaton, J Park, C Qiu, HR Warren, ES Torstenson, ...
Nature genetics 51 (1), 51-62, 2019
|Combining billing codes, clinical notes, and medications from electronic health records provides superior phenotyping performance|
JCD Wei-Qi Wei, Pedro L Teixeira, Huan Mo, Robert M Cronin, Jeremy L Warner
Journal of the American Medical Informatics Association, 2015
|Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record|
WQ Wei, LA Bastarache, RJ Carroll, JE Marlo, TJ Osterman, ER Gamazon, ...
PloS one 12 (7), e0175508, 2017
|Phenotype risk scores identify patients with unrecognized Mendelian disease patterns|
L Bastarache, JJ Hughey, S Hebbring, J Marlo, W Zhao, WT Ho, ...
Science 359 (6381), 1233-1239, 2018
|IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes|
Y Momozawa, J Dmitrieva, E Théâtre, V Deffontaine, S Rahmouni, ...
Nature communications 9 (1), 1-18, 2018
|Development and evaluation of an ensemble resource linking medications to their indications|
WQ Wei, RM Cronin, H Xu, TA Lasko, L Bastarache, JC Denny
Journal of the American Medical Informatics Association 20 (5), 954-961, 2013
|CNTRO: a semantic web ontology for temporal relation inferencing in clinical narratives|
C Tao, WQ Wei, HR Solbrig, G Savova, CG Chute
AMIA annual symposium proceedings 2010, 787, 2010
|Mapping ICD-10 and ICD-10-CM codes to phecodes: workflow development and initial evaluation|
P Wu, A Gifford, X Meng, X Li, H Campbell, T Varley, J Zhao, R Carroll, ...
JMIR medical informatics 7 (4), e14325, 2019
|Impact of data fragmentation across healthcare centers on the accuracy of a high-throughput clinical phenotyping algorithm for specifying subjects with type 2 diabetes mellitus|
WQ Wei, CL Leibson, JE Ransom, AN Kho, PJ Caraballo, HS Chai, ...
Journal of the American Medical Informatics Association 19 (2), 219-224, 2012
|Learning from longitudinal data in electronic health record and genetic data to improve cardiovascular event prediction|
J Zhao, QP Feng, P Wu, RA Lupu, RA Wilke, QS Wells, JC Denny, ...
Scientific reports 9 (1), 1-10, 2019
|LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins|
WQ Wei, X Li, Q Feng, M Kubo, IJ Kullo, PL Peissig, EW Karlson, ...
Circulation 138 (17), 1839-1849, 2018
|Evaluating electronic health record data sources and algorithmic approaches to identify hypertensive individuals|
PL Teixeira, WQ Wei, RM Cronin, H Mo, JP VanHouten, RJ Carroll, ...
Journal of the American Medical Informatics Association 24 (1), 162-171, 2017
|A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease|
CA Emdin, ME Haas, AV Khera, K Aragam, M Chaffin, D Klarin, G Hindy, ...
PLoS genetics 16 (4), e1008629, 2020
|GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network|
B Namjou, T Lingren, Y Huang, S Parameswaran, BL Cobb, IB Stanaway, ...
BMC medicine 17 (1), 1-19, 2019
|Harmonizing clinical sequencing and interpretation for the eMERGE III network|
H Zouk, E Venner, NJ Lennon, DM Muzny, D Abrams, S Adunyah, ...
The American Journal of Human Genetics 105 (3), 588-605, 2019