Terpenoid synthase structures: a so far incomplete view of complex catalysis Y Gao, RB Honzatko, RJ Peters Natural product reports 29 (10), 1153-1175, 2012 | 371 | 2012 |
Translesion and repair DNA polymerases: diverse structure and mechanism W Yang, Y Gao Annual review of biochemistry 87, 239-261, 2018 | 206 | 2018 |
Capture of a third Mg2+ is essential for catalyzing DNA synthesis Y Gao, W Yang science 352 (6291), 1334, 2016 | 171 | 2016 |
Structures and operating principles of the replisome Y Gao, Y Cui, T Fox, S Lin, H Wang, N de Val, ZH Zhou, W Yang Science 363 (6429), eaav7003, 2019 | 136 | 2019 |
Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis K Zhou, Y Gao, JA Hoy, FM Mann, RB Honzatko, RJ Peters Journal of Biological Chemistry 287 (9), 6840-6850, 2012 | 126 | 2012 |
A new paradigm of DNA synthesis: three-metal-ion catalysis (vol 6, 51, 2016) W Yang, PJ Weng, Y Gao CELL AND BIOSCIENCE 7, 2017 | 69* | 2017 |
How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis YS Lee, Y Gao, Y Wei NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2015 | 49 | 2015 |
Different mechanisms for translocation by monomeric and hexameric helicases Y Gao, W Yang Current opinion in structural biology 61, 25-32, 2020 | 40 | 2020 |
Engineered LwaCas13a with enhanced collateral activity for nucleic acid detection J Yang, Y Song, X Deng, JA Vanegas, Z You, Y Zhang, Z Weng, L Avery, ... Nature Chemical Biology 19 (1), 45-54, 2023 | 36 | 2023 |
Structural basis of the stereoselective formation of the spirooxindole ring in the biosynthesis of citrinadins Z Liu, F Zhao, B Zhao, J Yang, J Ferrara, B Sankaran, ... Nature communications 12 (1), 4158, 2021 | 24 | 2021 |
Replisome structure suggests mechanism for continuous fork progression and post-replication repair W Yang, MM Seidman, WD Rupp, Y Gao DNA repair 81, 102658, 2019 | 20 | 2019 |
Detection of reaction intermediates in Mg2+-dependent DNA synthesis and RNA degradation by time-resolved X-ray crystallography NL Samara, Y Gao, J Wu, W Yang Methods in enzymology 592, 283-327, 2017 | 19 | 2017 |
Functional analysis of the bacteriophage T4 Rad50 homolog (gp46) coiled-coil domain T Barfoot, TJ Herdendorf, BR Behning, BA Stohr, Y Gao, KN Kreuzer, ... Journal of Biological Chemistry 290 (39), 23905-23915, 2015 | 18 | 2015 |
Bypassing a 8, 5′-cyclo-2′-deoxyadenosine lesion by human DNA polymerase η at atomic resolution PJ Weng, Y Gao, MT Gregory, P Wang, Y Wang, W Yang Proceedings of the National Academy of Sciences 115 (42), 10660-10665, 2018 | 17 | 2018 |
Multiple deprotonation paths of the nucleophile 3′-OH in the DNA synthesis reaction MT Gregory, Y Gao, Q Cui, W Yang Proceedings of the National Academy of Sciences 118 (23), e2103990118, 2021 | 16 | 2021 |
In crystallo observation of three metal ion promoted DNA polymerase misincorporation C Chang, C Lee Luo, Y Gao Nature Communications 13 (1), 2346, 2022 | 13 | 2022 |
Central cavity of fructose-1, 6-bisphosphatase and the evolution of AMP/fructose 2, 6-bisphosphate synergism in eukaryotic organisms Y Gao, L Shen, RB Honzatko Journal of Biological Chemistry 289 (12), 8450-8461, 2014 | 12 | 2014 |
DNA helicase–polymerase coupling in bacteriophage DNA replication CY Lo, Y Gao Viruses 13 (9), 1739, 2021 | 10 | 2021 |
Structural basis for the activation of a compact CRISPR-Cas13 nuclease X Deng, E Osikpa, J Yang, SJ Oladeji, J Smith, X Gao, Y Gao Nature Communications 14 (1), 5845, 2023 | 9 | 2023 |
Early drug discovery and development of novel cancer therapeutics targeting DNA Polymerase eta (POLH) DM Wilson III, MAJ Duncton, C Chang, CL Luo, TM Georgiadis, ... Frontiers in Oncology, 4776, 2021 | 9 | 2021 |