Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia RC Trembath, JR Thomson, RD Machado, NV Morgan, C Atkinson, ... New England Journal of Medicine 345 (5), 325-334, 2001 | 920 | 2001 |
Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor C Atkinson, S Stewart, PD Upton, R Machado, JR Thomson, RC Trembath, ... Circulation 105 (14), 1672-1678, 2002 | 821 | 2002 |
Dysfunctional Smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension X Yang, L Long, M Southwood, N Rudarakanchana, PD Upton, TK Jeffery, ... Circulation research 96 (10), 1053-1063, 2005 | 449 | 2005 |
Polymers of Z α1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivo R Mahadeva, C Atkinson, Z Li, S Stewart, S Janciauskiene, DG Kelley, ... The American journal of pathology 166 (2), 377-386, 2005 | 218 | 2005 |
Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection C Atkinson, H Song, B Lu, F Qiao, TA Burns, VM Holers, GC Tsokos, ... The Journal of clinical investigation 115 (9), 2444-2453, 2005 | 207 | 2005 |
Smoke exposure causes endoplasmic reticulum stress and lipid accumulation in retinal pigment epithelium through oxidative stress and complement activation K Kunchithapautham, C Atkinson, B Rohrer Journal of Biological Chemistry 289 (21), 14534-14546, 2014 | 171 | 2014 |
Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension RD Machado, N Rudarakanchana, C Atkinson, JA Flanagan, R Harrison, ... Human molecular genetics 12 (24), 3277-3286, 2003 | 161 | 2003 |
A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice S He, C Atkinson, F Qiao, K Cianflone, X Chen, S Tomlinson The Journal of clinical investigation 119 (8), 2304-2316, 2009 | 157 | 2009 |
A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury Y Huang, F Qiao, C Atkinson, VM Holers, S Tomlinson The Journal of Immunology 181 (11), 8068-8076, 2008 | 141 | 2008 |
Investigation of Second Genetic Hits at the BMPR2 Locus as a Modulator of Disease Progression in Familial Pulmonary Arterial Hypertension RD Machado, V James, M Southwood, RE Harrison, C Atkinson, ... Circulation 111 (5), 607-613, 2005 | 118 | 2005 |
Complement-dependent P-selectin expression and injury following ischemic stroke C Atkinson, H Zhu, F Qiao, JC Varela, J Yu, H Song, MS Kindy, ... The Journal of Immunology 177 (10), 7266-7274, 2006 | 116 | 2006 |
Murine Kupffer cells are protective in total hepatic ischemia/reperfusion injury with bowel congestion through IL-10 JD Ellett, C Atkinson, ZP Evans, Z Amani, E Balish, MG Schmidt, ... The Journal of Immunology 184 (10), 5849-5858, 2010 | 109 | 2010 |
Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts C Atkinson, B Floerchinger, F Qiao, S Casey, T Williamson, E Moseley, ... Circulation 127 (12), 1290-1299, 2013 | 107 | 2013 |
Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma F Qiao, C Atkinson, H Song, R Pannu, I Singh, S Tomlinson The American journal of pathology 169 (3), 1039-1047, 2006 | 99 | 2006 |
Cigarette smoke exposure is associated with vitamin D3 deficiencies in patients with chronic rhinosinusitis JK Mulligan, W Nagel, BP O'Connell, J Wentzel, C Atkinson, RJ Schlosser Journal of Allergy and Clinical Immunology 134 (2), 342-349. e1, 2014 | 97 | 2014 |
The alternative complement pathway propagates inflammation and injury in murine ischemic stroke A Elvington, C Atkinson, H Zhu, J Yu, K Takahashi, GL Stahl, MS Kindy, ... The Journal of Immunology 189 (9), 4640-4647, 2012 | 95 | 2012 |
Microvascular changes in small airways predispose to obliterative bronchiolitis after lung transplantation H Luckraz, M Goddard, K McNeil, C Atkinson, SC Charman, S Stewart, ... The Journal of heart and lung transplantation 23 (5), 527-531, 2004 | 91 | 2004 |
Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy KM Marshall, S He, Z Zhong, C Atkinson, S Tomlinson Journal of Experimental Medicine 211 (9), 1793-1805, 2014 | 88 | 2014 |
Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice C Atkinson, F Qiao, H Song, GS Gilkeson, S Tomlinson The Journal of Immunology 180 (2), 1231-1238, 2008 | 88 | 2008 |
Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice A Elvington, C Atkinson, L Kulik, H Zhu, J Yu, MS Kindy, VM Holers, ... The Journal of Immunology 188 (3), 1460-1468, 2012 | 87 | 2012 |